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  1. Apr 04, 2011
  2. Jan 03, 2011
  3. Sep 22, 2010
  4. Aug 06, 2010
  5. Jul 18, 2010
  6. Jul 04, 2010
    • Aaron's avatar
      Fixed logic relating to "split" coverage. · 9fe56c08
      Aaron authored
      	1. Fixed bug in BamAncillary::getBamBlocks where the switch statement was misbehaving.  Changed to if/else
      	2. Added countSplitHits to bedFile class to proper count coverage from "blocked" alignments. Previously, coverage
                 was counted separately for __each__ block yet what we actually want is the base coverage to be counted for each block,
                 but we only want the blocks to be treated as __one__ alignment or feature.
      	3. Updated coverageBed to use getBamBlocks.
      9fe56c08
  7. Jun 30, 2010
    • Aaron's avatar
      Multiple changes. · 184656c1
      Aaron authored
      	1.  Added support for VCF 4.0.  BED.end is based on the size of the REF allele in the VCF entry.
      	2.  Fixed a bug in BamReader.cpp that bombed when seq and qual are == "*"
      	3.  Changed the Makefiles to inherit flags from the master Makefile in the root directory.
      	4.  Fixed a bug in bedToBam to created incorrect CIGAR strings for the first block.
      184656c1
  8. Jun 29, 2010
  9. Jun 07, 2010
    • Aaron's avatar
      Large, performance-related commit. · f792d8eb
      Aaron authored
      	1. Created separate structs for BED and BEDCOV in order to reduce memory consumption.  Savings of ~30%.
      	2. Changed the binning approach to make 16kb bins the most granular.  IntersectBed is now 1/3 faster as a result.
      	3. Templated the parsing and reporting functions in bedFile.  Had to move them to the header file to avoid linker complications.
      	4. Added CHRPOS as a common type.
      f792d8eb
  10. May 04, 2010
  11. Apr 26, 2010
  12. Apr 15, 2010
  13. Mar 23, 2010
  14. Mar 17, 2010
    • Aaron's avatar
      Improvements to coverageBed · f733cafd
      Aaron authored
      	1. Added the -hist option (credit to Jose Bras).
      	2. Substantially improved the speed by using a depth iterator instead of copying the depth map for each feature in B when computing coverage.
      f733cafd
  15. Jan 03, 2010
  16. Jan 01, 2010
  17. Dec 30, 2009
    • Aaron's avatar
      Updated coverageBed and bedFile.cpp · d9fcb67c
      Aaron authored
      	1. Revised usage to 80 chars
      	2. GPL headers
      	3. Added new stdin logic
      	4. Changes logo.
      	5. Updated bedFile.cpp's loadBedIntoMapBin to support stdin.
      d9fcb67c
  18. Dec 20, 2009
    • Aaron's avatar
      GFF support seems to work. Improved bedFile.cpp. · c0d4e8a4
      Aaron authored
      	1. Got parseGffLine working
      	2. Added GFF support to the reportBed* methods.
      	3. Cleaned up the stdin / parsing logic and centralized it within bedFile.cpp.
      	This removes some of the complexity from each of the tools and tidies the codebase
      	overall.
      c0d4e8a4
  19. Nov 18, 2009
  20. Nov 16, 2009
  21. Sep 18, 2009
    • Aaron's avatar
      Version 2.2.0 · 952c45ad
      Aaron authored
      === Notable changes in this release ===
      1.  coverageBed will optionally only count features in BED file A (e.g. sequencing reads) that overlap with
      	the intervals/windows in BED file B.  This has been requested several times recently and facilitates CHiP-Seq and
      	RNA-Seq experiments.
      
      2.  intersectBed can now require a minimum __reciprocal__ overlap between intervals in BED A and BED B.  For example,
      	previously, if one used -f 0.90, it required that a feature in B overlap 90% of the feature in A for the "hit"
      	to be reported.  If one adds the -r (reciprocal) option, the hit must also cover 90% of the feature in B.  This helps
      	to exclude overlaps between say small features in A and large features in B:
      
      	A ==========
      	B  **********************************************************
      
      	-f 0.50 (Reported), whereas -f 0.50 -r (Not reported)
      
      3.  The score field has been changed to be a string.  While this deviates from the UCSC definition, it allows one to track
      	much more meaningful information about a feature/interval.  For example, score could now be:
      
      	7.31E-05  (a p-value)
      	0.334577  (mean enrichment)
      	2:2.2:40:2 (several values encoded in a string)
      
      4.  closestBed now, by default, reports __all__ intervals in B that overlap equally with an interval in A.  Previously, it
      	merely reported the first such feature that appeared in B.  Here's a cartoon explaining the difference.
      
      	**Prior behavior**
      
      	A	 ==============
      	B.1        				++++++++++++++
      	B.2       				++++++++++++++
      	B.3               				+++++++++
      
      	-----------------------------------------
      	Result = B.1 			++++++++++++++
      
      	**Current behavior**
      
      	A	 ==============
      	B.1        				++++++++++++++
      	B.2       				++++++++++++++
      	B.3               				+++++++++
      
      	-----------------------------------------
      	Result = B.1 			++++++++++++++
      			 B.2 			++++++++++++++
      
      	Using the -t option, one can also choose to report either the first or the last entry in B in the event of a tie.
      
      5.  Several other minor changes to the algorithms have been made to increase speed a bit.
      952c45ad
  22. Sep 17, 2009
    • Aaron's avatar
      VERSION 2.1.2 · 572c76e0
      Aaron authored
      1. Fixed yet another bug in the parsing of "track" or "browser" lines.  Sigh...
      2. Change the "score" column (i.e. column 5) to b stored as a string.  While this deviates
         from the UCSC convention, it allows significantly more information to be packed into the column.
      572c76e0
  23. Jun 15, 2009
    • Aaron's avatar
      VERSION 2.1.0 · 23c77070
      Aaron authored
      	1. Fixed a bug in peIntersectBed that prevented -a from being correctly handled when passed via stdin.
      	2. Added new functionality to coverageBed that calculates the density of coverage.
      	3. Fixed bug in genomeCoverageBed.
      23c77070
  24. May 19, 2009
  25. May 05, 2009
    • Aaron Quinlan's avatar
      Strandedness. reportBed in bedFile. peIntersect · ac52b452
      Aaron Quinlan authored
      	1. Added strandedness to relevant programs (e.g. intersectBed, mergeBed, etc.)
      	2. Moved reportBed and reportBedRange to bedFile.cpp to clean up code
      	3. Sped up file parsing.  Added lineFileUtilities.cpp
      	4. Added peIntersectBed
      ac52b452
  26. Apr 26, 2009
  27. Apr 24, 2009
    • Aaron Quinlan's avatar
      First public source release. Version 1.1 · ff4edaf0
      Aaron Quinlan authored
      	1.  Added a README for installation
      	2.  Modified intersectBed and windowBed to call one function for
      	    finding overlaps.  This function is now called when reading
      	    from cin or from a file.
      	3.  Added acknowledgements.
      	4.  Corrected the PROGRAM_NAME in coverageBed
      ff4edaf0
  28. Apr 10, 2009
    • Aaron Quinlan's avatar
      coverageBed.cpp: · 319d42fd
      Aaron Quinlan authored
      	Changed the include from graphBed.h to coverageBed.h
      coverageMain.cpp:
              Changed the include from graphBed.h to coverageBed.h
      319d42fd
  29. Apr 09, 2009
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