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  1. Sep 16, 2011
  2. Sep 15, 2011
  3. Sep 07, 2011
  4. Jan 03, 2011
  5. Sep 22, 2010
  6. Aug 18, 2010
    • Aaron's avatar
      Big commit. · b9ab28d0
      Aaron authored
      	1. Added new version of BamTools supporting uncompressed BAM.
      	2. Added -ubam option to intersectBed.
      	3. First functional release of annotateBed.
      	4. Updated GetEditDistance calls to GetTag(NM) per the new API change in BamTools.
      b9ab28d0
  7. Jul 18, 2010
  8. Jun 29, 2010
  9. Jun 07, 2010
    • Aaron's avatar
      Large, performance-related commit. · f792d8eb
      Aaron authored
      	1. Created separate structs for BED and BEDCOV in order to reduce memory consumption.  Savings of ~30%.
      	2. Changed the binning approach to make 16kb bins the most granular.  IntersectBed is now 1/3 faster as a result.
      	3. Templated the parsing and reporting functions in bedFile.  Had to move them to the header file to avoid linker complications.
      	4. Added CHRPOS as a common type.
      f792d8eb
  10. Apr 15, 2010
  11. Apr 12, 2010
    • Aaron's avatar
      Added the -wao option to intersectBed. · 27234494
      Aaron authored
      	- Allows one to report 0 overlap for non-overlapping A features
      	- Changed all private memeber variables to use "_VAR" notation.
      	- Added convenience functions for reporting overlaps.
      27234494
  12. Mar 23, 2010
  13. Mar 15, 2010
  14. Feb 12, 2010
    • Aaron's avatar
      Fixed several bugs and improved BAM performance. · 2fe5a837
      Aaron authored
      	1. Fixed bug to "re-allow" track and "browser" lines.
      	2. Fixed bug in reporting BEDPE overlaps.
      	3. Fixed bug when using type "notboth" with BAM files in pairToBed.
      	4. When comparing BAM files to BED/GFF annotations with intersectBed or pairToBed, the __aligned__ sequence is used, rather than the __original__ sequence.
      2fe5a837
  15. Jan 04, 2010
  16. Dec 29, 2009
  17. Dec 20, 2009
    • Aaron's avatar
      GFF support seems to work. Improved bedFile.cpp. · c0d4e8a4
      Aaron authored
      	1. Got parseGffLine working
      	2. Added GFF support to the reportBed* methods.
      	3. Cleaned up the stdin / parsing logic and centralized it within bedFile.cpp.
      	This removes some of the complexity from each of the tools and tidies the codebase
      	overall.
      c0d4e8a4
  18. Sep 18, 2009
    • Aaron's avatar
      Version 2.2.0 · 952c45ad
      Aaron authored
      === Notable changes in this release ===
      1.  coverageBed will optionally only count features in BED file A (e.g. sequencing reads) that overlap with
      	the intervals/windows in BED file B.  This has been requested several times recently and facilitates CHiP-Seq and
      	RNA-Seq experiments.
      
      2.  intersectBed can now require a minimum __reciprocal__ overlap between intervals in BED A and BED B.  For example,
      	previously, if one used -f 0.90, it required that a feature in B overlap 90% of the feature in A for the "hit"
      	to be reported.  If one adds the -r (reciprocal) option, the hit must also cover 90% of the feature in B.  This helps
      	to exclude overlaps between say small features in A and large features in B:
      
      	A ==========
      	B  **********************************************************
      
      	-f 0.50 (Reported), whereas -f 0.50 -r (Not reported)
      
      3.  The score field has been changed to be a string.  While this deviates from the UCSC definition, it allows one to track
      	much more meaningful information about a feature/interval.  For example, score could now be:
      
      	7.31E-05  (a p-value)
      	0.334577  (mean enrichment)
      	2:2.2:40:2 (several values encoded in a string)
      
      4.  closestBed now, by default, reports __all__ intervals in B that overlap equally with an interval in A.  Previously, it
      	merely reported the first such feature that appeared in B.  Here's a cartoon explaining the difference.
      
      	**Prior behavior**
      
      	A	 ==============
      	B.1        				++++++++++++++
      	B.2       				++++++++++++++
      	B.3               				+++++++++
      
      	-----------------------------------------
      	Result = B.1 			++++++++++++++
      
      	**Current behavior**
      
      	A	 ==============
      	B.1        				++++++++++++++
      	B.2       				++++++++++++++
      	B.3               				+++++++++
      
      	-----------------------------------------
      	Result = B.1 			++++++++++++++
      			 B.2 			++++++++++++++
      
      	Using the -t option, one can also choose to report either the first or the last entry in B in the event of a tie.
      
      5.  Several other minor changes to the algorithms have been made to increase speed a bit.
      952c45ad
  19. May 05, 2009
    • Aaron Quinlan's avatar
      Strandedness. reportBed in bedFile. peIntersect · ac52b452
      Aaron Quinlan authored
      	1. Added strandedness to relevant programs (e.g. intersectBed, mergeBed, etc.)
      	2. Moved reportBed and reportBedRange to bedFile.cpp to clean up code
      	3. Sped up file parsing.  Added lineFileUtilities.cpp
      	4. Added peIntersectBed
      ac52b452
  20. Apr 24, 2009
    • Aaron Quinlan's avatar
      First public source release. Version 1.1 · ff4edaf0
      Aaron Quinlan authored
      	1.  Added a README for installation
      	2.  Modified intersectBed and windowBed to call one function for
      	    finding overlaps.  This function is now called when reading
      	    from cin or from a file.
      	3.  Added acknowledgements.
      	4.  Corrected the PROGRAM_NAME in coverageBed
      ff4edaf0
  21. Apr 23, 2009
  22. Apr 09, 2009
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