@@ -12,7 +12,7 @@ Phosphoproteomic data of mock-treated and SARS-CoV.2 infected cells were extract
Finally, we used Carnival ([Liu et al., 2019](https://doi.org/10.1038/s41540-019-0118-z)) with the COSMOS approach ([Dugourd et al., 2021](https://doi.org/10.15252/msb.20209730)) to connect the top 10 deregulated kinases with the top 30 deregulated TFs with a Prior Knowledge Network assembled from OmniPath resources ([Türei et al., 2021](https://doi.org/10.1101/2020.08.03.221242)). Progeny pathway activity scores were used to weigh the PKN and facilitate the optimal network search to connect kinases and TFs.
To place our results in the context of the whole study, we matched the genes obtained in carnival results with those included in the curated pathways by the [Covid-19 Disease map community](https://covid.pages.uni.lu/map_contents).
To place our results in the context of the whole study, we matched the genes obtained in carnival results with those included in the curated pathways by the [Covid-19 Disease map community](https://covid.pages.uni.lu/map_contents).