Update file README.md

README.md

@@ -44,9 +44,8 @@ The output diagrams can be access at http://hipathia.babelomics.org/covid19/, se
 
 * We have specifically selected as Pathway source: "Disease Maps Community curated-pathways"
 
-**Results CoV-Hipathia webtool COVID-19 diagrams **
+**Results CoV-Hipathia webtool COVID-19 diagrams**
 
-* Identified 77 out of 176 circuits in the COVID-19 disease map as differentially activated in infected versus non-infected individuals.
+* Identified 46 out of 175 circuits in the COVID-19 disease map as differentially activated in infected versus non-infected individuals.
 * Observed high activation in the Interferon-1 pathway, indicative of antiviral defense response. However, not all genes in this pathway are overexpressed, suggesting selective gene-driven activation.
-* Noted significant overactivation in the IFN-lambda signaling pathway, aligning with its role in innate antiviral responses and respiratory pathogen activity. This supports targeting this pathway as a potential treatment approach, as evidenced by Feld et al., 2021.
 * Found upregulation in the renin-angiotensin pathway, likely due to ACE2's interaction with SARS-CoV-2. This may contribute to increased vasoconstriction, as outlined in Vaduganathan et al., 2020.