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xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</body></html></celldesigner:notes> <celldesigner:annotation> <celldesigner:complexSpecies>s_id_csa1947</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> <celldesigner:proteinReference>p_s_id_sa11915</celldesigner:proteinReference> +<celldesigner:name>PPP3CA</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11905" name="CFL1"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: CFL1 -Name: cofilin 1 -Previous Symbols: CFL -HGNC_ID: 1874 -EntrezGene_ID: 1072 -RefSeq_ID: NM_005507 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11916" name="PPP3CB"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 0 + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</body></html></celldesigner:notes> +<celldesigner:annotation> +<celldesigner:complexSpecies>s_id_csa1947</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11916</celldesigner:proteinReference> 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+<celldesigner:proteinReference>p_s_id_sa11917</celldesigner:proteinReference> +<celldesigner:name>PPP3CC</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:annotation> +</celldesigner:species> +<celldesigner:species id="s_id_sa11907" name="GRIA4"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: GRIA4 +Name: glutamate ionotropic receptor AMPA type subunit 4 +Previous Symbols: GLUR4 +Synonyms: GLURD, GluA4 +HGNC_ID: 4574 +EntrezGene_ID: 2893 +RefSeq_ID: NM_000829 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" 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xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000165410"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:hgnc:4573"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CFL2"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:GRIA3"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> 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+</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1892</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11895</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1900</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11909</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>GRIA1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11894" name="PRKACA"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: PRKACA -Name: protein kinase cAMP-activated catalytic 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rdf:resource="urn:miriam:ensembl:ENSG00000120251"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5566"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:2891"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1892</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11894</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1900</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11910</celldesigner:proteinReference> +<celldesigner:name>GRIA2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11893" name="PRKACB"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: PRKACB -Name: protein kinase cAMP-activated catalytic subunit beta -Synonyms: PKACb -HGNC_ID: 9381 -EntrezGene_ID: 5567 -RefSeq_ID: NM_182948 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11889" name="CASP8_space_(p18)"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: CASP8 +Name: caspase 8 +Synonyms: Casp-8, FLICE, MACH, MCH5 +HGNC_ID: 1509 +EntrezGene_ID: 841 +RefSeq_ID: NM_001228 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000142875"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:hgnc:1509"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P22694"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CASP8"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9381"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q14790"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PRKACB"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:841"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_182948"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_001228"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5567"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000064012"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1892</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11893</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1890</celldesigner:complexSpecies> 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0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P18146"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:hgnc:1509"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1958"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CASP8"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:3238"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q14790"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:EGR1"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:841"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000120738"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_001228"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001964"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000064012"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1944</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> 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huntingtin +Previous Symbols: HD +Synonyms: IT15 +HGNC_ID: 4851 +EntrezGene_ID: 3064 +RefSeq_ID: NM_002111 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9318"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:uniprot:P42858"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PPP3R2"/> +<rdf:li rdf:resource="urn:miriam:hgnc:4851"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q96LZ3"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:3064"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5535"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002111"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_147180"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000197386"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000188386"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:HTT"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1946</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11914</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1897</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11903</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfStructuralStates> +<celldesigner:structuralState structuralState="mutated polyQ">mutated polyQ</celldesigner:structuralState></celldesigner:listOfStructuralStates> +</celldesigner:state> +<celldesigner:name>HTT</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11913" name="PPP3R1"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: PPP3R1 -Name: protein phosphatase 3 regulatory subunit B, alpha -Synonyms: CALNB1, CNB, CNB1 -HGNC_ID: 9317 -EntrezGene_ID: 5534 -RefSeq_ID: NM_000945 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11904" name="CTNNB1"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: CTNNB1 +Name: catenin beta 1 +Previous Symbols: CTNNB +Synonyms: armadillo, beta-catenin +HGNC_ID: 2514 +EntrezGene_ID: 1499 +RefSeq_ID: NM_001098210 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9317"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CTNNB1"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PPP3R1"/> +<rdf:li rdf:resource="urn:miriam:hgnc:2514"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_000945"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_001098210"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000221823"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000168036"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P63098"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P35222"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5534"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:1499"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1946</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11913</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1897</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11904</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>CTNNB1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11912" name="ADCY5"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: ADCY5 -Name: adenylate cyclase 5 -Synonyms: AC5 -HGNC_ID: 236 -EntrezGene_ID: 111 -RefSeq_ID: NM_183357 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11884" name="PRKACA"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: PRKACA +Name: protein kinase cAMP-activated catalytic subunit alpha +Synonyms: PKACa +HGNC_ID: 9380 +EntrezGene_ID: 5566 +RefSeq_ID: NM_002730 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 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-SemanticZoomLevelVisibility: 3 +<celldesigner:species id="s_id_sa11905" name="CFL1"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: CFL1 +Name: cofilin 1 +Previous Symbols: CFL +HGNC_ID: 1874 +EntrezGene_ID: 1072 +RefSeq_ID: NM_005507 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> 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xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> -<rdf:Description rdf:about="#"/></rdf:RDF> -</body> -</html> -</celldesigner:notes> -<celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1914</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:proteinReference>p_s_id_sa11936</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1899</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11905</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>CFL1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11941" name="CREB1"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: CREB1 -Name: cAMP responsive element binding protein 1 -HGNC_ID: 2345 -EntrezGene_ID: 1385 -RefSeq_ID: NM_134442 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11906" name="CFL2"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: CFL2 +Name: cofilin 2 +Synonyms: NEM7 +HGNC_ID: 1875 +EntrezGene_ID: 1073 +RefSeq_ID: NM_138638 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_134442"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000165410"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:2345"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CFL2"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1385"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q9Y281"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CREB1"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:1073"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P16220"/> +<rdf:li rdf:resource="urn:miriam:hgnc:1875"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000118260"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_138638"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1920</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11941</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1899</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11906</celldesigner:proteinReference> <celldesigner:state> <celldesigner:listOfModifications> -<celldesigner:modification residue="rs1" state="phosphorylated"/> </celldesigner:listOfModifications> </celldesigner:state> +<celldesigner:name>CFL2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11934" name="CAPNS1"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: CAPNS1 -Name: calpain small subunit 1 -Previous Symbols: CAPN4 -Synonyms: 30K, CANP, CANPS, CDPS -HGNC_ID: 1481 -EntrezGene_ID: 826 -RefSeq_ID: NM_001003962 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11898" name="AHCYL1"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: AHCYL1 +Name: adenosylhomocysteinase like 1 +Synonyms: IRBIT, PPP1R78, XPVKONA +HGNC_ID: 344 +EntrezGene_ID: 10768 +RefSeq_ID: NM_001242673 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:1481"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000168710"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000126247"/> +<rdf:li rdf:resource="urn:miriam:uniprot:O43865"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CAPNS1"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_001242673"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P04632"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:10768"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001003962"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:AHCYL1"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:826"/> +<rdf:li rdf:resource="urn:miriam:hgnc:344"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1912</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11934</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1895</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11898</celldesigner:proteinReference> +<celldesigner:name>AHCYL1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11933" name="CAPN1"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: CAPN1 -Name: calpain 1 -Synonyms: CANP, CANPL1, muCANP, muCL -HGNC_ID: 1476 -EntrezGene_ID: 823 -RefSeq_ID: NM_001198868 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11899" name="ITPR3"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: ITPR3 +Name: inositol 1,4,5-trisphosphate receptor type 3 +Synonyms: IP3R3 +HGNC_ID: 6182 +EntrezGene_ID: 3710 +RefSeq_ID: NM_002224 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:823"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002224"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000014216"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:ITPR3"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:1476"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q14573"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CAPN1"/> +<rdf:li rdf:resource="urn:miriam:hgnc:6182"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001198868"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:3710"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P07384"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000096433"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1912</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11933</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1895</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11899</celldesigner:proteinReference> +<celldesigner:name>ITPR3</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11897" name="CFL1"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: CFL1 -Name: cofilin 1 -Previous Symbols: CFL -HGNC_ID: 1874 -EntrezGene_ID: 1072 -RefSeq_ID: NM_005507 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11925" name="GRIA1"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: GRIA1 +Name: glutamate ionotropic receptor AMPA type subunit 1 +Previous Symbols: GLUR1 +Synonyms: GLURA, GluA1 +HGNC_ID: 4571 +EntrezGene_ID: 2890 +RefSeq_ID: NM_000827 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000172757"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:uniprot:P42261"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CFL1"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:GRIA1"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1072"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_000827"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:1874"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000155511"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P23528"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:2890"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_005507"/> +<rdf:li rdf:resource="urn:miriam:hgnc:4571"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1894</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11897</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1907</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11925</celldesigner:proteinReference> <celldesigner:state> <celldesigner:listOfModifications> -<celldesigner:modification residue="rs1" state="phosphorylated"/> +<celldesigner:modification residue="rs1" state="phosphorylated"> </celldesigner:modification> </celldesigner:listOfModifications> </celldesigner:state> +<celldesigner:name>GRIA1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11896" name="CFL2"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: CFL2 -Name: cofilin 2 -Synonyms: NEM7 -HGNC_ID: 1875 -EntrezGene_ID: 1073 -RefSeq_ID: NM_138638 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11926" name="GRIA2"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: GRIA2 +Name: glutamate ionotropic receptor AMPA type subunit 2 +Previous Symbols: GLUR2 +Synonyms: GLURB, GluA2 +HGNC_ID: 4572 +EntrezGene_ID: 2891 +RefSeq_ID: NM_000826 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000165410"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:uniprot:P42262"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CFL2"/> +<rdf:li rdf:resource="urn:miriam:hgnc:4572"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q9Y281"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:GRIA2"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1073"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_000826"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:1875"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000120251"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_138638"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:2891"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1894</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11896</celldesigner:proteinReference> -<celldesigner:state> -<celldesigner:listOfModifications> -<celldesigner:modification residue="rs1" state="phosphorylated"/> -</celldesigner:listOfModifications> -</celldesigner:state> +<celldesigner:complexSpecies>s_id_csa1907</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11926</celldesigner:proteinReference> +<celldesigner:name>GRIA2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11939" name="RAP1GAP"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: RAP1GAP -Name: RAP1 GTPase activating protein -Previous Symbols: RAP1GA1 -Synonyms: KIAA0474, RAP1GAP1, RAP1GAPII -HGNC_ID: 9858 -EntrezGene_ID: 5909 -RefSeq_ID: NM_002885 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11927" name="GRIA4"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: GRIA4 +Name: glutamate ionotropic receptor AMPA type subunit 4 +Previous Symbols: GLUR4 +Synonyms: GLURD, GluA4 +HGNC_ID: 4574 +EntrezGene_ID: 2893 +RefSeq_ID: NM_000829 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002885"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:hgnc:4574"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RAP1GAP"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000152578"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P47736"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:GRIA4"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9858"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_000829"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000076864"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P48058"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5909"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:2893"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1917</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11939</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1907</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11927</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +<celldesigner:modification residue="rs1" state="phosphorylated"> </celldesigner:modification> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>GRIA4</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11938" name="RAP1GAP2"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: RAP1GAP2 -Name: RAP1 GTPase activating protein 2 -Previous Symbols: GARNL4 -Synonyms: KIAA1039 -HGNC_ID: 29176 -EntrezGene_ID: 23108 -RefSeq_ID: NM_015085, NM_001100398 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11928" name="GRIA3"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: GRIA3 +Name: glutamate ionotropic receptor AMPA type subunit 3 +Previous Symbols: GLUR3 +Synonyms: GLURC, GluA3, MRX94 +HGNC_ID: 4573 +EntrezGene_ID: 2892 +RefSeq_ID: NM_000828 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000132359"/></rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RAP1GAP2"/> +<rdf:li rdf:resource="urn:miriam:hgnc:4573"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q684P5"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:GRIA3"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:23108"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000125675"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_015085"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_000828"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001100398"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:2892"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:29176"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P42263"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1917</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11938</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1907</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11928</celldesigner:proteinReference> +<celldesigner:name>GRIA3</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11935" name="PPP1CA"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: PPP1CA -Name: protein phosphatase 1 catalytic subunit alpha -Previous Symbols: PPP1A -Synonyms: PP-1A, PP1A, PP1alpha -HGNC_ID: 9281 -EntrezGene_ID: 5499 -RefSeq_ID: NM_002708 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> -<rdf:Description rdf:about="#"> -<bqbiol:isDescribedBy> +<celldesigner:species id="s_id_sa11911" name="HTT"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: HTT +Name: huntingtin +Previous Symbols: HD +Synonyms: IT15 +HGNC_ID: 4851 +EntrezGene_ID: 3064 +RefSeq_ID: NM_002111 +SemanticZoomLevelVisibility: 3 +TransparencyZoomLevelVisibility: 0 + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002708"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:uniprot:P42858"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9281"/> +<rdf:li rdf:resource="urn:miriam:hgnc:4851"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5499"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:3064"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000172531"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002111"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P62136"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000197386"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PPP1CA"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:HTT"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1913</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11935</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1902</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11911</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfStructuralStates> +<celldesigner:structuralState structuralState="mutated polyQ">mutated polyQ</celldesigner:structuralState></celldesigner:listOfStructuralStates> +</celldesigner:state> +<celldesigner:name>HTT</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11957" name="PPP1CA"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: PPP1CA -Name: protein phosphatase 1 catalytic subunit alpha -Previous Symbols: PPP1A -Synonyms: PP-1A, PP1A, PP1alpha -HGNC_ID: 9281 -EntrezGene_ID: 5499 -RefSeq_ID: NM_002708 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11938" name="RAP1GAP2"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: RAP1GAP2 +Name: RAP1 GTPase activating protein 2 +Previous Symbols: GARNL4 +Synonyms: KIAA1039 +HGNC_ID: 29176 +EntrezGene_ID: 23108 +RefSeq_ID: NM_015085 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002708"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000132359"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9281"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RAP1GAP2"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5499"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q684P5"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000172531"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:23108"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P62136"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_015085"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PPP1CA"/> +<rdf:li rdf:resource="urn:miriam:hgnc:29176"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1928</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11957</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1917</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11938</celldesigner:proteinReference> +<celldesigner:name>RAP1GAP2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11886" name="PRKACG"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: PRKACG -Name: protein kinase cAMP-activated catalytic subunit gamma -Synonyms: PKACg -HGNC_ID: 9382 -EntrezGene_ID: 5568 -RefSeq_ID: NM_002732 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11939" name="RAP1GAP"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: RAP1GAP +Name: RAP1 GTPase activating protein +Previous Symbols: RAP1GA1 +Synonyms: KIAA0474, RAP1GAP1, RAP1GAPII +HGNC_ID: 9858 +EntrezGene_ID: 5909 +RefSeq_ID: NM_002885 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000165059"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002885"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P22612"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RAP1GAP"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PRKACG"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P47736"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9382"/> +<rdf:li rdf:resource="urn:miriam:hgnc:9858"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5568"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000076864"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002732"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:5909"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1945</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11886</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1917</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11939</celldesigner:proteinReference> +<celldesigner:name>RAP1GAP</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11884" name="PRKACA"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: PRKACA -Name: protein kinase cAMP-activated catalytic subunit alpha -Synonyms: PKACa -HGNC_ID: 9380 -EntrezGene_ID: 5566 -RefSeq_ID: NM_002730 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11931" name="PPP2CA"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 0 + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</body></html></celldesigner:notes> +<celldesigner:annotation> +<celldesigner:complexSpecies>s_id_csa1911</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11931</celldesigner:proteinReference> +<celldesigner:name>PPP2CA</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:annotation> +</celldesigner:species> +<celldesigner:species id="s_id_sa11932" name="PPP2CB"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 0 + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</body></html></celldesigner:notes> +<celldesigner:annotation> +<celldesigner:complexSpecies>s_id_csa1911</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11932</celldesigner:proteinReference> +<celldesigner:name>PPP2CB</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:annotation> +</celldesigner:species> +<celldesigner:species id="s_id_sa11945" name="KCNN2"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: KCNN2 +Name: potassium calcium-activated channel subfamily N member 2 +Synonyms: KCa2.2, hSK2 +HGNC_ID: 6291 +EntrezGene_ID: 3781 +RefSeq_ID: NM_021614 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002730"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000080709"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9380"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:3781"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P17612"/> +<rdf:li rdf:resource="urn:miriam:hgnc:6291"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000072062"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q9H2S1"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PRKACA"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:KCNN2"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5566"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_021614"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1945</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11884</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1924</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11945</celldesigner:proteinReference> +<celldesigner:name>KCNN2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11885" name="PRKACB"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: PRKACB -Name: protein kinase cAMP-activated catalytic subunit beta -Synonyms: PKACb -HGNC_ID: 9381 -EntrezGene_ID: 5567 -RefSeq_ID: NM_182948 -SemanticZoomLevelVisibility: 5 +<celldesigner:species id="s_id_sa11946" name="KCNN1"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: KCNN1 +Name: potassium calcium-activated channel subfamily N member 1 +Synonyms: KCa2.1, hSK1 +HGNC_ID: 6290 +EntrezGene_ID: 3780 +RefSeq_ID: NM_002248 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000142875"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000105642"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P22694"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q92952"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9381"/> +<rdf:li rdf:resource="urn:miriam:hgnc:6290"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PRKACB"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:3780"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_182948"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002248"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5567"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:KCNN1"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1945</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11885</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1924</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11946</celldesigner:proteinReference> +<celldesigner:name>KCNN1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11947" name="KCNN3"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: KCNN3 +<celldesigner:species id="s_id_sa11947" name="KCNN3"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: KCNN3 Name: potassium calcium-activated channel subfamily N member 3 Synonyms: KCa2.3, SKCA3, hSK3 HGNC_ID: 6292 EntrezGene_ID: 3782 RefSeq_ID: NM_002249 -SemanticZoomLevelVisibility: 3 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:KCNN3"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:KCNN3"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> @@ -1850,5922 +1941,2661 @@ TransparencyZoomLevelVisibility: 0 </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> <celldesigner:complexSpecies>s_id_csa1924</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> <celldesigner:proteinReference>p_s_id_sa11947</celldesigner:proteinReference> +<celldesigner:name>KCNN3</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11946" name="KCNN1"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: KCNN1 -Name: potassium calcium-activated channel subfamily N member 1 -Synonyms: KCa2.1, hSK1 -HGNC_ID: 6290 -EntrezGene_ID: 3780 -RefSeq_ID: NM_002248 -SemanticZoomLevelVisibility: 3 +<celldesigner:species id="s_id_sa11893" name="PRKACB"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: PRKACB +Name: protein kinase cAMP-activated catalytic subunit beta +Synonyms: PKACb +HGNC_ID: 9381 +EntrezGene_ID: 5567 +RefSeq_ID: NM_182948 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000105642"/></rdf:Bag> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000142875"/> +</rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q92952"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P22694"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:6290"/> +<rdf:li rdf:resource="urn:miriam:hgnc:9381"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:3780"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PRKACB"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002248"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_182948"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:KCNN1"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:5567"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> -</body> -</html> -</celldesigner:notes> +</body></html></celldesigner:notes> <celldesigner:annotation> -<celldesigner:complexSpecies>s_id_csa1924</celldesigner:complexSpecies> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11946</celldesigner:proteinReference> +<celldesigner:complexSpecies>s_id_csa1892</celldesigner:complexSpecies> +<celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11893</celldesigner:proteinReference> +<celldesigner:name>PRKACB</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> -<celldesigner:species id="s_id_sa11945" name="KCNN2"> -<celldesigner:notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body> -Symbol: KCNN2 -Name: potassium calcium-activated channel subfamily N member 2 -Synonyms: KCa2.2, hSK2 -HGNC_ID: 6291 -EntrezGene_ID: 3781 -RefSeq_ID: NM_021614 -SemanticZoomLevelVisibility: 3 +<celldesigner:species id="s_id_sa11894" name="PRKACA"><celldesigner:notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: PRKACA +Name: protein kinase cAMP-activated catalytic subunit alpha +Synonyms: PKACa +HGNC_ID: 9380 +EntrezGene_ID: 5566 +RefSeq_ID: NM_002730 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> + +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#"> 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xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: endoplasmic reticulum membrane -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 7 -The lipid bilayer surrounding the endoplasmic reticulum. -</body> -</html> -</notes> +<compartment metaid="s_id_ca187" id="s_id_ca187" name="ER" size="1" units="volume" outside="default" > <annotation> <celldesigner:extension> <celldesigner:name>ER</celldesigner:name> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_ca187"> +<rdf:Description rdf:about="#"> <bqbiol:is> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005789"/> @@ -7774,136 +4604,90 @@ The lipid bilayer surrounding the endoplasmic reticulum. </rdf:Description> </rdf:RDF> </annotation> +<notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 7 + +</body></html></notes> </compartment> -<compartment metaid="default" id="default" size="1" units="volume"/> -</listOfCompartments> -<listOfSpecies> -<species metaid="s_id_sa11795" id="s_id_sa11795" name="cAMP" compartment="s_id_ca188" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: 3',5'-cyclic AMP -Synonyms: 3', 5'-Cyclic AMP, adenosine 3', 5'-cyclic monophosphate, Adenosine 3', 5'-cyclic phosphate, Adenosine 3', 5'-phosphate, ADENOSINE-3', 5'-CYCLIC-MONOPHOSPHATE, cAMP, Cyclic adenylic acid, Cyclic AMP, Recon metabolite: camp -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -<a href="http://vmh.uni.lu/#metabolite/camp">camp</a> -</body> -</html> -</notes> +<compartment metaid="default" id="default" name="" size="1" units="volume" > <annotation> <celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> -<celldesigner:name>cAMP</celldesigner:name> -</celldesigner:speciesIdentity> +<celldesigner:name></celldesigner:name> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11795"> -<bqbiol:is> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A17489"/> -</rdf:Bag> -</bqbiol:is> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species> -<species metaid="s_id_sa11824" id="s_id_sa11824" name="FOS" compartment="s_id_ca182" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: FOS -Name: Fos proto-oncogene, AP-1 transcription factor subunit -Synonyms: AP-1, c-fos -HGNC_ID: 3796 -EntrezGene_ID: 2353 -RefSeq_ID: NM_005252 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>RNA</celldesigner:class> -<celldesigner:rnaReference>r_s_id_sa11824</celldesigner:rnaReference> +<notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body> +</body></html></notes> +</compartment> +</listOfCompartments> +<listOfSpecies><species name="Ca2_plus_" id="s_id_sa11768" metaid="s_id_sa11768" initialAmount="0.0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>ION</celldesigner:class> +<celldesigner:name>Ca2_plus_</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11824"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:3796"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000170345"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_005252"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P01100"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:2353"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="CSNK1A1" id="s_id_sa11781" metaid="s_id_sa11781" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11781</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +<celldesigner:modification residue="rs1" state="phosphorylated"> </celldesigner:modification> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>CSNK1A1</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="cAMP" id="s_id_sa11840" metaid="s_id_sa11840" initialAmount="0.0" charge="0" compartment="s_id_ca169"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: 3',5'-cyclic AMP +Synonyms: 3', 5'-Cyclic AMP, adenosine 3', 5'-cyclic monophosphate, Adenosine 3', 5'-cyclic phosphate, Adenosine 3', 5'-phosphate, ADENOSINE-3', 5'-CYCLIC-MONOPHOSPHATE, cAMP, Cyclic adenylic acid, Cyclic AMP, Recon metabolite: camp +SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 0 +Charge: 0 + +VMH database: <a href="http://vmh.uni.lu/#metabolite/camp">camp</a></body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>cAMP</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:is> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:FOS"/> +<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A17489"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:is> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11697" id="s_id_sa11697" name="BTRC" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: BTRC +<species name="BTRC" id="s_id_sa11749" metaid="s_id_sa11749" initialAmount="0.0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: BTRC Name: beta-transducin repeat containing E3 ubiquitin protein ligase Synonyms: FBXW1A, Fwd1, bTrCP, bTrCP1, beta-TrCP1, betaTrCP HGNC_ID: 1144 EntrezGene_ID: 8945 RefSeq_ID: NM_033637 -SemanticZoomLevelVisibility: 3 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11697</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11749</celldesigner:proteinReference> +<celldesigner:name>BTRC</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5795"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11697"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000166167"/> @@ -7938,2478 +4722,1897 @@ TransparencyZoomLevelVisibility: 0 </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11787" id="s_id_sa11787" name="RASGRP2" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: RASGRP2 -Name: RAS guanyl releasing protein 2 -Synonyms: CALDAG-GEFI -HGNC_ID: 9879 -EntrezGene_ID: 10235 -RefSeq_ID: NM_153819 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11787</celldesigner:proteinReference> +<species name="CSNK1A1" id="s_id_sa11843" metaid="s_id_sa11843" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11843</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>CSNK1A1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11787"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_153819"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="HTR6" id="s_id_sa11790" metaid="s_id_sa11790" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11790</celldesigner:proteinReference> +<celldesigner:name>HTR6</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="PP1" id="s_id_csa1941" metaid="s_id_csa1941" initialAmount="0.0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>PP1</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RASGRP2"/> +<rdf:li rdf:resource="urn:miriam:mesh:D054645"/> </rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="PPP1R1B" id="s_id_sa11772" metaid="s_id_sa11772" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11772</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +<celldesigner:modification residue="rs2" state="phosphorylated"> </celldesigner:modification> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>PPP1R1B</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="GABA" id="s_id_sa11776" metaid="s_id_sa11776" initialAmount="0.0" charge="0" compartment="s_id_ca183"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>GABA</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9879"/> +<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A16865"/> </rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="Phospholipase_space_C" id="s_id_sa11734" metaid="s_id_sa11734" initialAmount="0.0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11734</celldesigner:proteinReference> +<celldesigner:name>Phospholipase_space_C</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:hasPart> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q7LDG7"/> +<rdf:li rdf:resource="urn:miriam:interpro:IPR001192"/> </rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</bqbiol:hasPart> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="PTPN5" id="s_id_sa11783" metaid="s_id_sa11783" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11783</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>PTPN5</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="Calcineurin" id="s_id_csa1914" metaid="s_id_csa1914" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>Calcineurin</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000068831"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0004723"/> </rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:10235"/> +<rdf:li rdf:resource="urn:miriam:mesh:D019703"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11857" id="s_id_sa11857" name="CAMK4" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: CAMK4 -Name: calcium/calmodulin dependent protein kinase IV -Synonyms: CaMK-GR -HGNC_ID: 1464 -EntrezGene_ID: 814 -RefSeq_ID: NM_001744 -SemanticZoomLevelVisibility: 5 +<species name="cAMP" id="s_id_sa11703" metaid="s_id_sa11703" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: 3',5'-cyclic AMP +Synonyms: 3', 5'-Cyclic AMP, adenosine 3', 5'-cyclic monophosphate, Adenosine 3', 5'-cyclic phosphate, Adenosine 3', 5'-phosphate, ADENOSINE-3', 5'-CYCLIC-MONOPHOSPHATE, cAMP, Cyclic adenylic acid, Cyclic AMP, Recon metabolite: camp 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xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11857"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000152495"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:is> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q16566"/> +<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A17489"/> </rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</bqbiol:is> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="ERK1_slash_2" id="s_id_csa1910" metaid="s_id_csa1910" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>ERK1_slash_2</celldesigner:name> 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id="s_id_csa1935" metaid="s_id_csa1935" initialAmount="0.0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>Calcineurin</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CAMK4"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0004723"/> </rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001744"/> +<rdf:li rdf:resource="urn:miriam:mesh:D019703"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11842" id="s_id_sa11842" name="ARPP21" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: ARPP21 -Name: cAMP regulated phosphoprotein 21 -Synonyms: ARPP-21, R3HDM3, TARPP -HGNC_ID: 16968 -EntrezGene_ID: 10777 -RefSeq_ID: NM_198399 -SemanticZoomLevelVisibility: 5 +<species name="RANBP9" id="s_id_sa11754" metaid="s_id_sa11754" initialAmount="0.0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: RANBP9 +Name: RAN binding protein 9 +Synonyms: RanBPM +HGNC_ID: 13727 +EntrezGene_ID: 10048 +RefSeq_ID: NM_005493 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> 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rdf:resource="urn:miriam:ncbigene:10777"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_005493"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:16968"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RANBP9"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_198399"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:10048"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_csa1899" id="s_id_csa1899" name="cofilin" compartment="s_id_ca169" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>cofilin</celldesigner:name> -</celldesigner:speciesIdentity> -</celldesigner:extension> -</annotation> -</species> -<species metaid="s_id_sa11755" id="s_id_sa11755" name="ITPR2" compartment="s_id_ca187" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: ITPR2 -Name: inositol 1,4,5-trisphosphate receptor type 2 -Synonyms: CFAP48, IP3R2 -HGNC_ID: 6181 -EntrezGene_ID: 3709 -RefSeq_ID: NM_002223 -SemanticZoomLevelVisibility: 7 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11755</celldesigner:proteinReference> +<species name="Ca2_plus_" id="s_id_sa11769" metaid="s_id_sa11769" initialAmount="0.0" compartment="default"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>ION</celldesigner:class> +<celldesigner:name>Ca2_plus_</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5834"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11755"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002223"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q14571"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:ITPR2"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:3709"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:6181"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000123104"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11766" id="s_id_sa11766" name="GRM1" compartment="s_id_ca188" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: GRM1 -Name: glutamate metabotropic receptor 1 -Synonyms: GPRC1A, MGLUR1, PPP1R85, mGlu1 -HGNC_ID: 4593 -EntrezGene_ID: 2911 -RefSeq_ID: NM_000838 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11766</celldesigner:proteinReference> +<species name="synaptic_space_plasticity" id="s_id_sa11810" metaid="s_id_sa11810" initialAmount="0.0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>synaptic_space_plasticity</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11766"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:GRM1"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:2911"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q13255"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_000838"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000152822"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:4593"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0031915"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11811" id="s_id_sa11811" name="PPP1R1B" compartment="s_id_ca182" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PPP1R1B -Name: protein phosphatase 1 regulatory inhibitor subunit 1B -Synonyms: DARPP-32, FLJ20940 -HGNC_ID: 9287 -EntrezGene_ID: 84152 -RefSeq_ID: NM_032192 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11811</celldesigner:proteinReference> +<species name="chromatin_space_organization" id="s_id_sa11799" metaid="s_id_sa11799" initialAmount="0.0" charge="0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>chromatin_space_organization</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11811"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_032192"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000131771"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q9UD71"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PPP1R1B"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9287"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:84152"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0006325"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11764" id="s_id_sa11764" name="RANBP9" compartment="s_id_ca169" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: RANBP9 -Name: RAN binding protein 9 -Synonyms: RanBPM -HGNC_ID: 13727 -EntrezGene_ID: 10048 -RefSeq_ID: NM_005493 -SemanticZoomLevelVisibility: 5 +<species name="EEF2K" id="s_id_sa11711" metaid="s_id_sa11711" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: EEF2K +Name: eukaryotic elongation factor 2 kinase +Synonyms: eEF-2K +HGNC_ID: 24615 +EntrezGene_ID: 29904 +RefSeq_ID: NM_013302 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11764</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11711</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>EEF2K</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11764"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:13727"/> +<rdf:li rdf:resource="urn:miriam:hgnc:24615"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000010017"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_013302"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q96S59"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:EEF2K"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_005493"/> +<rdf:li rdf:resource="urn:miriam:uniprot:O00418"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RANBP9"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000103319"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:10048"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:29904"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11827" id="s_id_sa11827" name="PDYN" compartment="s_id_ca182" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PDYN -Name: prodynorphin -Previous Symbols: SCA23 -Synonyms: ADCA, PENKB -HGNC_ID: 8820 -EntrezGene_ID: 5173 -RefSeq_ID: NM_001190892 -SemanticZoomLevelVisibility: 5 +<species name="PRKAR2B" id="s_id_sa11730" metaid="s_id_sa11730" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: PRKAR2B +Name: protein kinase cAMP-dependent type II regulatory subunit beta +Previous Symbols: PRKAR2 +HGNC_ID: 9392 +EntrezGene_ID: 5577 +RefSeq_ID: NM_002736 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>RNA</celldesigner:class> -<celldesigner:rnaReference>r_s_id_sa11827</celldesigner:rnaReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11730</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>PRKAR2B</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11827"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001190892"/> +<rdf:li rdf:resource="urn:miriam:hgnc:9392"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:8820"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P31323"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P01213"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000005249"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5173"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PRKAR2B"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PDYN"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002736"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000101327"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:5577"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11750" id="s_id_sa11750" name="DRD1" compartment="s_id_ca169" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: DRD1 -Name: dopamine receptor D1 -HGNC_ID: 3020 -EntrezGene_ID: 1812 -RefSeq_ID: NM_000794 -SemanticZoomLevelVisibility: 5 +<species name="RASGRP2" id="s_id_sa11760" metaid="s_id_sa11760" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: RASGRP2 +Name: RAS guanyl releasing protein 2 +Synonyms: CALDAG-GEFI +HGNC_ID: 9879 +EntrezGene_ID: 10235 +RefSeq_ID: NM_153819 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11750</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11760</celldesigner:proteinReference> <celldesigner:state> <celldesigner:listOfModifications> -<celldesigner:modification residue="rs1" state="phosphorylated"/> +<celldesigner:modification residue="rs1" state="phosphorylated"> </celldesigner:modification> </celldesigner:listOfModifications> </celldesigner:state> +<celldesigner:name>RASGRP2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11750"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:DRD1"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_153819"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_000794"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RASGRP2"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1812"/> +<rdf:li rdf:resource="urn:miriam:hgnc:9879"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000184845"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q7LDG7"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:3020"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000068831"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P21728"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:10235"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11773" id="s_id_sa11773" name="PPP1R1B" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PPP1R1B -Name: protein phosphatase 1 regulatory inhibitor subunit 1B -Synonyms: DARPP-32, FLJ20940 -HGNC_ID: 9287 -EntrezGene_ID: 84152 -RefSeq_ID: NM_032192 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11773</celldesigner:proteinReference> -<celldesigner:state> -<celldesigner:listOfModifications> -<celldesigner:modification residue="rs2" state="phosphorylated"/> -</celldesigner:listOfModifications> -</celldesigner:state> +<species name="acetylcholine" id="s_id_sa11832" metaid="s_id_sa11832" initialAmount="0.0" compartment="default"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>acetylcholine</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11773"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_032192"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000131771"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q9UD71"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PPP1R1B"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9287"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:84152"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_csa1892" id="s_id_csa1892" name="PKA_space_catalytic_space_subunit" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>PKA_space_catalytic_space_subunit</celldesigner:name> +<species name="Calmodulin" id="s_id_csa1916" metaid="s_id_csa1916" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>Calmodulin</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5880"/> -<celldesigner:catalyzed reaction="re5797"/> -<celldesigner:catalyzed reaction="re5952"/> -<celldesigner:catalyzed reaction="re5854"/> -<celldesigner:catalyzed reaction="re5842"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1892"> +<rdf:Description rdf:about="#"> <bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ec-code:2.7.11.11"/> +<rdf:li rdf:resource="urn:miriam:mesh:D002147"/> </rdf:Bag> </bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11847" id="s_id_sa11847" name="cannabinoid" compartment="default" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: cannabinoid -Synonyms: cannabinoids -SemanticZoomLevelVisibility: 3 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> -<celldesigner:name>cannabinoid</celldesigner:name> +<species name="PPP1R1B" id="s_id_sa11811" metaid="s_id_sa11811" initialAmount="0.0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11811</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>PPP1R1B</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11847"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A67194"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11809" id="s_id_sa11809" name="long_minus_term_space_memory" compartment="s_id_ca182" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> 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+<bqbiol:isEncodedBy> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0004016"/> +</rdf:Bag> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11788" id="s_id_sa11788" name="Ca2_plus_" compartment="s_id_ca169" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: calcium(2+) -Synonyms: Ca(2+), Ca2+, Ca(2+), CALCIUM ION, calcium, doubly charged positive ion -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>ION</celldesigner:class> -<celldesigner:name>Ca2_plus_</celldesigner:name> +<species name="PP1" id="s_id_csa1928" metaid="s_id_csa1928" initialAmount="0.0" 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</rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11725" id="s_id_sa11725" name="dendritic_space_spine_space_development" compartment="s_id_ca169" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: dendritic spine development -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PHENOTYPE</celldesigner:class> -<celldesigner:name>dendritic_space_spine_space_development</celldesigner:name> +<species name="PP1" id="s_id_csa1913" metaid="s_id_csa1913" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>PP1</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11725"> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0060996"/> +<rdf:li rdf:resource="urn:miriam:mesh:D054645"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11794" id="s_id_sa11794" name="TRPV1" compartment="s_id_ca188" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: TRPV1 -Name: transient receptor potential cation channel subfamily V member 1 -Previous Symbols: VR1 -HGNC_ID: 12716 -EntrezGene_ID: 7442 -RefSeq_ID: NM_018727 -SemanticZoomLevelVisibility: 5 +<species name="postsynaptic_space_response" id="s_id_sa11717" metaid="s_id_sa11717" initialAmount="0.0" charge="0" compartment="s_id_ca168"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: excitatory postsynaptic potential +SemanticZoomLevelVisibility: 6 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11794</celldesigner:proteinReference> + +A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>postsynaptic_space_response</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11794"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:12716"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:7442"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:TRPV1"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000196689"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q8NER1"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_018727"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0060079"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11723" id="s_id_sa11723" name="PRKCD" compartment="s_id_ca169" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PRKCD -Name: protein kinase C delta -HGNC_ID: 9399 -EntrezGene_ID: 5580 -RefSeq_ID: NM_001316327 -SemanticZoomLevelVisibility: 5 +<species name="PPP1R1B" id="s_id_sa11786" metaid="s_id_sa11786" initialAmount="0.0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11786</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +<celldesigner:modification residue="rs2" state="phosphorylated"> </celldesigner:modification> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>PPP1R1B</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="TF_space_EGR1" id="s_id_csa1944" metaid="s_id_csa1944" initialAmount="0.0" charge="0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>TF_space_EGR1</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="RANBP9" id="s_id_sa11764" metaid="s_id_sa11764" initialAmount="0.0" charge="0" compartment="s_id_ca169"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: RANBP9 +Name: RAN binding protein 9 +Synonyms: RanBPM +HGNC_ID: 13727 +EntrezGene_ID: 10048 +RefSeq_ID: NM_005493 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11723</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11764</celldesigner:proteinReference> +<celldesigner:name>RANBP9</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5807"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11723"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PRKCD"/> +<rdf:li rdf:resource="urn:miriam:hgnc:13727"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q05655"/> +<rdf:li 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xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: LRRK2 -Name: leucine rich repeat kinase 2 -Previous Symbols: PARK8 -Synonyms: DKFZp434H2111, FLJ45829, RIPK7, ROCO2 -HGNC_ID: 18618 -EntrezGene_ID: 120892 -RefSeq_ID: XM_058513 -SemanticZoomLevelVisibility: 6 +<species name="PTPN5" id="s_id_sa11784" metaid="s_id_sa11784" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11784</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +<celldesigner:modification residue="rs1" state="phosphorylated"> </celldesigner:modification> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>PTPN5</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="EEF2K" id="s_id_sa11708" metaid="s_id_sa11708" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: EEF2K +Name: eukaryotic elongation factor 2 kinase +Synonyms: eEF-2K +HGNC_ID: 24615 +EntrezGene_ID: 29904 +RefSeq_ID: NM_013302 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> 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</celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11710"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:120892"/> +<rdf:li rdf:resource="urn:miriam:hgnc:24615"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q5S007"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_013302"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:18618"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:EEF2K"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:XM_058513"/> +<rdf:li rdf:resource="urn:miriam:uniprot:O00418"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000188906"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000103319"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:LRRK2"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:29904"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_csa1897" id="s_id_csa1897" name="CTNNB1:HTT" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>CTNNB1:HTT</celldesigner:name> -</celldesigner:speciesIdentity> 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xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11765"> -<bqbiol:is> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/> -</rdf:Bag> -</bqbiol:is> -</rdf:Description> -</rdf:RDF> -</annotation> -</species> -<species metaid="s_id_csa1931" id="s_id_csa1931" name="PKA" compartment="s_id_ca188" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: cAMP-dependent protein kinase complex -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 7 -An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>PKA</celldesigner:name> -</celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5803"/> -</celldesigner:listOfCatalyzedReactions> -</celldesigner:extension> -<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1931"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005952"/> -</rdf:Bag> -</bqbiol:isEncodedBy> -</rdf:Description> -</rdf:RDF> -</annotation> -</species> -<species metaid="s_id_sa11810" id="s_id_sa11810" name="synaptic_space_plasticity" compartment="s_id_ca182" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: positive regulation of synaptic plasticity -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PHENOTYPE</celldesigner:class> -<celldesigner:name>synaptic_space_plasticity</celldesigner:name> +<species name="ARPP21" id="s_id_sa11842" metaid="s_id_sa11842" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11842</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +<celldesigner:modification residue="rs1" state="phosphorylated"> </celldesigner:modification> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>ARPP21</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11810"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0031915"/> -</rdf:Bag> -</bqbiol:isEncodedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11706" id="s_id_sa11706" name="Ca2_plus_" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: calcium(2+) -Synonyms: Ca(2+), Ca2+, Ca(2+), CALCIUM ION, calcium, doubly charged positive ion -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>ION</celldesigner:class> -<celldesigner:name>Ca2_plus_</celldesigner:name> +<species name="PPP1R1B" id="s_id_sa11771" metaid="s_id_sa11771" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11771</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>PPP1R1B</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11706"> -<bqbiol:is> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/> -</rdf:Bag> -</bqbiol:is> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11858" id="s_id_sa11858" name="PENK" compartment="default" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PENK -Name: proenkephalin -HGNC_ID: 8831 -EntrezGene_ID: 5179 -RefSeq_ID: NM_001135690 +<species name="HTT" id="s_id_sa11738" metaid="s_id_sa11738" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: HTT +Name: huntingtin +Previous Symbols: HD +Synonyms: IT15 +HGNC_ID: 4851 +EntrezGene_ID: 3064 +RefSeq_ID: NM_002111 SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11858</celldesigner:proteinReference> +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11738</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfStructuralStates> +<celldesigner:structuralState structuralState="mutated 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rdf:resource="urn:miriam:refseq:NM_001135690"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:3064"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5179"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002111"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P01210"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000197386"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000181195"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:HTT"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_csa1944" id="s_id_csa1944" name="TF_space_EGR1" compartment="s_id_ca182" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>TF_space_EGR1</celldesigner:name> -</celldesigner:speciesIdentity> -</celldesigner:extension> -</annotation> -</species> -<species metaid="s_id_sa11770" id="s_id_sa11770" name="cellular_space_calcium" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PHENOTYPE</celldesigner:class> -<celldesigner:name>cellular_space_calcium</celldesigner:name> -</celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5869"/> -</celldesigner:listOfCatalyzedReactions> -</celldesigner:extension> -<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11770"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0006874"/> -</rdf:Bag> -</bqbiol:isEncodedBy> -</rdf:Description> -</rdf:RDF> -</annotation> -</species> -<species metaid="s_id_sa11836" id="s_id_sa11836" name="PPP1R1B" compartment="s_id_ca182" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PPP1R1B -Name: protein phosphatase 1 regulatory inhibitor subunit 1B -Synonyms: DARPP-32, FLJ20940 -HGNC_ID: 9287 -EntrezGene_ID: 84152 -RefSeq_ID: NM_032192 -SemanticZoomLevelVisibility: 5 +<species name="DRD1" id="s_id_sa11750" metaid="s_id_sa11750" initialAmount="0.0" charge="0" compartment="s_id_ca169"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: DRD1 +Name: dopamine receptor D1 +HGNC_ID: 3020 +EntrezGene_ID: 1812 +RefSeq_ID: NM_000794 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>RNA</celldesigner:class> -<celldesigner:rnaReference>r_s_id_sa11836</celldesigner:rnaReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11750</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +<celldesigner:modification residue="rs1" state="phosphorylated"> </celldesigner:modification> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>DRD1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11836"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_032192"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:DRD1"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000131771"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_000794"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q9UD71"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:1812"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PPP1R1B"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000184845"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9287"/> +<rdf:li rdf:resource="urn:miriam:hgnc:3020"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:84152"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P21728"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11793" id="s_id_sa11793" name="CNR1" compartment="s_id_ca188" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: CNR1 -Name: cannabinoid receptor 1 -Previous Symbols: CNR -Synonyms: CANN6, CB-R, CB1, CB1A, CB1K5 -HGNC_ID: 2159 -EntrezGene_ID: 1268 -RefSeq_ID: NM_001160226 -SemanticZoomLevelVisibility: 5 +<species name="ITGB1" id="s_id_sa11707" metaid="s_id_sa11707" initialAmount="0.0" charge="0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: ITGB1 +Name: integrin subunit beta 1 +Previous Symbols: FNRB, MSK12, MDF2 +Synonyms: CD29, GPIIA +HGNC_ID: 6153 +EntrezGene_ID: 3688 +RefSeq_ID: NM_002211 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11793</celldesigner:proteinReference> +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11707</celldesigner:proteinReference> +<celldesigner:name>ITGB1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11793"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CNR1"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002211"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001160226"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P05556"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:2159"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:ITGB1"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000118432"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:3688"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P21554"/> +<rdf:li rdf:resource="urn:miriam:hgnc:6153"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1268"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000150093"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11775" id="s_id_sa11775" name="s391" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>DEGRADED</celldesigner:class> -<celldesigner:name>s391</celldesigner:name> +<species name="ROCK" id="s_id_csa1906" metaid="s_id_csa1906" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>ROCK</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> </celldesigner:speciesIdentity> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isPartOf> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:interpro:IPR020684"/> +</rdf:Bag> +</bqbiol:isPartOf> +</rdf:Description> +</rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11741" id="s_id_sa11741" name="GNAL" compartment="s_id_ca169" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: GNAL -Name: G protein subunit alpha L -HGNC_ID: 4388 -EntrezGene_ID: 2774 -RefSeq_ID: NM_182978, NM_002071 -SemanticZoomLevelVisibility: 5 +<species name="AHCYL1" id="s_id_sa11757" metaid="s_id_sa11757" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: AHCYL1 +Name: adenosylhomocysteinase like 1 +Synonyms: IRBIT, PPP1R78, XPVKONA +HGNC_ID: 344 +EntrezGene_ID: 10768 +RefSeq_ID: NM_001242673 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11741</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11757</celldesigner:proteinReference> +<celldesigner:name>AHCYL1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11741"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:4388"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:GNAL"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000168710"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P38405"/> +<rdf:li rdf:resource="urn:miriam:uniprot:O43865"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_182978"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_001242673"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002071"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:10768"/> </rdf:Bag> </bqbiol:isDescribedBy> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:interpro:IPR000367"/> -</rdf:Bag> -</bqbiol:isEncodedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000141404"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:AHCYL1"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:2774"/> +<rdf:li rdf:resource="urn:miriam:hgnc:344"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_csa1915" id="s_id_csa1915" name="PKA_space_catalytic_space_subunit" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>PKA_space_catalytic_space_subunit</celldesigner:name> +<species name="TF_space_CREB" id="s_id_csa1920" metaid="s_id_csa1920" initialAmount="0.0" charge="0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>TF_space_CREB</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="PKA" id="s_id_csa1931" metaid="s_id_csa1931" initialAmount="0.0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: cAMP-dependent protein kinase complex +SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 7 + +An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>PKA</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1915"> +<rdf:Description rdf:about="#"> <bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ec-code:2.7.11.11"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005952"/> </rdf:Bag> </bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11720" id="s_id_sa11720" name="CTNNB1" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: CTNNB1 -Name: catenin beta 1 -Previous Symbols: CTNNB -Synonyms: armadillo, beta-catenin -HGNC_ID: 2514 -EntrezGene_ID: 1499 -RefSeq_ID: NM_001098210 +<species name="VIM" id="s_id_sa11745" metaid="s_id_sa11745" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: VIM +Name: vimentin +HGNC_ID: 12692 +EntrezGene_ID: 7431 +RefSeq_ID: NM_003380 SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11720</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11745</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +<celldesigner:modification residue="rs1" state="phosphorylated"> </celldesigner:modification> +<celldesigner:modification residue="rs2" state="phosphorylated"> </celldesigner:modification> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>VIM</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11720"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CTNNB1"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:7431"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:2514"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_003380"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001098210"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000026025"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000168036"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P08670"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P35222"/> +<rdf:li rdf:resource="urn:miriam:hgnc:12692"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1499"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:VIM"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_csa1941" id="s_id_csa1941" name="PP1" compartment="s_id_ca188" initialAmount="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>PP1</celldesigner:name> +<species name="CaMKII" id="s_id_csa1937" metaid="s_id_csa1937" initialAmount="0.0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:state> +<celldesigner:listOfStructuralStates> +<celldesigner:structuralState structuralState="phosphorylated">phosphorylated</celldesigner:structuralState></celldesigner:listOfStructuralStates> +</celldesigner:state> +<celldesigner:name>CaMKII</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> </annotation> </species> -<species metaid="s_id_csa1903" id="s_id_csa1903" name="adenylyl_space_cyclase" compartment="s_id_ca169" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>innerSurface</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> +<species name="Ca2_plus_" id="s_id_sa11724" metaid="s_id_sa11724" initialAmount="0.0" compartment="s_id_ca187"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>ION</celldesigner:class> +<celldesigner:name>Ca2_plus_</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="AMPA_space_receptor" id="s_id_csa1900" metaid="s_id_csa1900" initialAmount="0.0" charge="0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: AMPA glutamate receptor complex +SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 4 +Charge: 0 + +An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>AMPA_space_receptor</celldesigner:name> <celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>adenylyl_space_cyclase</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5968"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1903"> +<rdf:Description rdf:about="#"> <bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ec-code:4.6.1.1"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0032281"/> </rdf:Bag> </bqbiol:isEncodedBy> -<bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="Ca2_plus_" id="s_id_sa11706" metaid="s_id_sa11706" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>ION</celldesigner:class> +<celldesigner:name>Ca2_plus_</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="RASGRF1" id="s_id_sa11821" metaid="s_id_sa11821" initialAmount="0.0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11821</celldesigner:proteinReference> +<celldesigner:name>RASGRF1</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0004016"/> +<rdf:li rdf:resource="urn:miriam:pubmed:16467520"/> </rdf:Bag> -</bqbiol:isEncodedBy> +</bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11745" id="s_id_sa11745" name="VIM" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: VIM -Name: vimentin -HGNC_ID: 12692 -EntrezGene_ID: 7431 -RefSeq_ID: NM_003380 -SemanticZoomLevelVisibility: 3 +<species name="PINK1" id="s_id_sa11712" metaid="s_id_sa11712" initialAmount="0.0" charge="0" compartment="s_id_ca168"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: PINK1 +Name: PTEN induced putative kinase 1 +Previous Symbols: PARK6 +HGNC_ID: 14581 +EntrezGene_ID: 65018 +RefSeq_ID: NM_032409 +SemanticZoomLevelVisibility: 6 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11745</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11712</celldesigner:proteinReference> <celldesigner:state> <celldesigner:listOfModifications> -<celldesigner:modification residue="rs1" state="phosphorylated"/> -<celldesigner:modification residue="rs2" state="phosphorylated"/> </celldesigner:listOfModifications> </celldesigner:state> +<celldesigner:name>PINK1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11745"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:7431"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:65018"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_003380"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q9BXM7"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000026025"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PINK1"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P08670"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000158828"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:12692"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_032409"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:VIM"/> +<rdf:li rdf:resource="urn:miriam:hgnc:14581"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11826" id="s_id_sa11826" name="EGR1" compartment="s_id_ca182" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: EGR1 -Name: early growth response 1 -Synonyms: AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 -HGNC_ID: 3238 -EntrezGene_ID: 1958 -RefSeq_ID: NM_001964 -SemanticZoomLevelVisibility: 5 +<species name="ITPR1" id="s_id_sa11713" metaid="s_id_sa11713" initialAmount="0.0" charge="0" compartment="s_id_ca187"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: ITPR1 +Name: inositol 1,4,5-trisphosphate receptor type 1 +Previous Symbols: SCA15, SCA16, SCA29 +Synonyms: ACV, IP3R1, Insp3r1, PPP1R94 +HGNC_ID: 6180 +EntrezGene_ID: 3708 +RefSeq_ID: NM_002222 +SemanticZoomLevelVisibility: 7 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>RNA</celldesigner:class> -<celldesigner:rnaReference>r_s_id_sa11826</celldesigner:rnaReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11713</celldesigner:proteinReference> +<celldesigner:name>ITPR1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11826"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P18146"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002222"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1958"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:ITPR1"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:3238"/> +<rdf:li rdf:resource="urn:miriam:hgnc:6180"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:EGR1"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:3708"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000120738"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000150995"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001964"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q14643"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11761" id="s_id_sa11761" name="K_plus_" compartment="default" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: potassium(1+) -Synonyms: K(+), K+, K(+), POTASSIUM ION -SemanticZoomLevelVisibility: 3 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>ION</celldesigner:class> -<celldesigner:name>K_plus_</celldesigner:name> +<species name="EGR1" id="s_id_sa11826" metaid="s_id_sa11826" initialAmount="0.0" charge="0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>RNA</celldesigner:class> +<celldesigner:rnaReference>r_s_id_sa11826</celldesigner:rnaReference> +<celldesigner:name>EGR1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11761"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29103"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_csa1923" id="s_id_csa1923" name="L_minus_type_space_calcium_space_channel_BR_Cav1.3_space_and_space_Cav1.2" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>outerSurface</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>L_minus_type_space_calcium_space_channel_BR_Cav1.3_space_and_space_Cav1.2</celldesigner:name> +<species name="Caspase_minus_8" id="s_id_csa1890" metaid="s_id_csa1890" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>Caspase_minus_8</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5851"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1923"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:interpro:IPR005446"/> -</rdf:Bag> -</bqbiol:isEncodedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11839" id="s_id_sa11839" name="ATP" compartment="s_id_ca169" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: ATP -Synonyms: Adenosine 5'-triphosphate, Adenosine triphosphate, ADENOSINE-5'-TRIPHOSPHATE, Adephos, Adetol, Adynol, Atipi, ATP, Atriphos, Cardenosine, Fosfobion, Glucobasin, H4atp, Myotriphos, Triadenyl, Triphosphaden, Recon metabolite: atp -SemanticZoomLevelVisibility: 5 +<species name="cAMP" id="s_id_sa11795" metaid="s_id_sa11795" initialAmount="0.0" charge="0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: 3',5'-cyclic AMP +Synonyms: 3', 5'-Cyclic AMP, adenosine 3', 5'-cyclic monophosphate, Adenosine 3', 5'-cyclic phosphate, Adenosine 3', 5'-phosphate, ADENOSINE-3', 5'-CYCLIC-MONOPHOSPHATE, cAMP, Cyclic adenylic acid, Cyclic AMP, Recon metabolite: camp +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 Charge: 0 -<a href="http://vmh.uni.lu/#metabolite/atp">atp</a> -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> -<celldesigner:name>ATP</celldesigner:name> + +VMH database: <a href="http://vmh.uni.lu/#metabolite/camp">camp</a></body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>cAMP</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11839"> +<rdf:Description rdf:about="#"> <bqbiol:is> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A15422"/> +<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A17489"/> </rdf:Bag> </bqbiol:is> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11726" id="s_id_sa11726" name="LRRK2" compartment="s_id_ca188" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: LRRK2 -Name: leucine rich repeat kinase 2 -Previous Symbols: PARK8 -Synonyms: DKFZp434H2111, FLJ45829, RIPK7, ROCO2 -HGNC_ID: 18618 -EntrezGene_ID: 120892 -RefSeq_ID: XM_058513 -SemanticZoomLevelVisibility: 5 +<species name="K_plus_" id="s_id_sa11761" metaid="s_id_sa11761" initialAmount="0.0" compartment="default"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>ION</celldesigner:class> +<celldesigner:name>K_plus_</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="PPP1R1B" id="s_id_sa11836" metaid="s_id_sa11836" initialAmount="0.0" charge="0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>RNA</celldesigner:class> +<celldesigner:rnaReference>r_s_id_sa11836</celldesigner:rnaReference> +<celldesigner:name>PPP1R1B</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="cannabinoid" id="s_id_sa11847" metaid="s_id_sa11847" initialAmount="0.0" compartment="default"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>cannabinoid</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="IP3_space_" id="s_id_sa11736" metaid="s_id_sa11736" initialAmount="0.0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: 1D-myo-inositol 1,4,5-trisphosphate +Synonyms: 1, 4, 5-Insp3, 1D-myo-Inositol 1, 4, 5-trisphosphate, D-myo-Inositol 1, 4, 5-trisphosphate, D-MYO-INOSITOL-1, 4, 5-TRIPHOSPHATE, Inositol 1, 4, 5-trisphosphate, Ins(1, 4, 5)P3, InsP3, IP3, Recon metabolite: mi145p +SemanticZoomLevelVisibility: 6 TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11726</celldesigner:proteinReference> + +VMH database: <a href="http://vmh.uni.lu/#metabolite/mi145p">mi145p</a></body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>IP3_space_</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5803"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11726"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:120892"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q5S007"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:18618"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:XM_058513"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000188906"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:is> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:LRRK2"/> +<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A16595"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:is> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11708" id="s_id_sa11708" name="EEF2K" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: EEF2K -Name: eukaryotic elongation factor 2 kinase -Synonyms: eEF-2K -HGNC_ID: 24615 -EntrezGene_ID: 29904 -RefSeq_ID: NM_013302 -SemanticZoomLevelVisibility: 5 +<species name="PRKAR2B" id="s_id_sa11751" metaid="s_id_sa11751" initialAmount="0.0" charge="0" compartment="s_id_ca168"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: PRKAR2B +Name: protein kinase cAMP-dependent type II regulatory subunit beta +Previous Symbols: PRKAR2 +HGNC_ID: 9392 +EntrezGene_ID: 5577 +RefSeq_ID: NM_002736 +SemanticZoomLevelVisibility: 6 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11708</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11751</celldesigner:proteinReference> <celldesigner:state> <celldesigner:listOfModifications> -<celldesigner:modification residue="rs1" state="phosphorylated"/> +<celldesigner:modification residue="rs1" state="phosphorylated"> </celldesigner:modification> </celldesigner:listOfModifications> </celldesigner:state> +<celldesigner:name>PRKAR2B</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11708"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:24615"/> +<rdf:li rdf:resource="urn:miriam:hgnc:9392"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_013302"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P31323"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:EEF2K"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000005249"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:O00418"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PRKAR2B"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000103319"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002736"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:29904"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:5577"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_csa1902" id="s_id_csa1902" name="inclusion" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>inclusion</celldesigner:name> +<species name="CTNNB1:HTT" id="s_id_csa1897" metaid="s_id_csa1897" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>CTNNB1:HTT</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11843" id="s_id_sa11843" name="CSNK1A1" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: CSNK1A1 -Name: casein kinase 1 alpha 1 -Synonyms: CK1, CK1a, CK1alpha, CKIa, CKIalpha -HGNC_ID: 2451 -EntrezGene_ID: 1452 -RefSeq_ID: NM_001892 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11843</celldesigner:proteinReference> +<species name="TRPV1" id="s_id_sa11794" metaid="s_id_sa11794" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11794</celldesigner:proteinReference> +<celldesigner:name>TRPV1</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5865"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11843"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CSNK1A1"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001892"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:2451"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P48729"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1452"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000113712"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11737" id="s_id_sa11737" name="VIM" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: VIM -Name: vimentin -HGNC_ID: 12692 -EntrezGene_ID: 7431 -RefSeq_ID: NM_003380 -SemanticZoomLevelVisibility: 3 +<species name="diglyceride" id="s_id_sa11733" metaid="s_id_sa11733" initialAmount="0.0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: diglyceride +Synonyms: a diacylglycerol, di-O-acylglycerols, Diacylglycerol, diacylglycerols, Diglyceride, diglycerides +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11737</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>innerSurface</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>diglyceride</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11737"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:7431"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_003380"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000026025"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P08670"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:12692"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:is> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:VIM"/> +<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A18035"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:is> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11834" id="s_id_sa11834" name="PP2C" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:proteinReference>p_s_id_sa11834</celldesigner:proteinReference> +<species name="CAMK4" id="s_id_sa11857" metaid="s_id_sa11857" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11857</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>CAMK4</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5865"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11834"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:interpro:IPR015655"/> -</rdf:Bag> -</bqbiol:isEncodedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11707" id="s_id_sa11707" name="ITGB1" compartment="s_id_ca188" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: ITGB1 -Name: integrin subunit beta 1 -Previous Symbols: FNRB, MSK12, MDF2 -Synonyms: CD29, GPIIA -HGNC_ID: 6153 -EntrezGene_ID: 3688 -RefSeq_ID: NM_002211 -SemanticZoomLevelVisibility: 5 +<species name="RAP1A" id="s_id_sa11808" metaid="s_id_sa11808" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11808</celldesigner:proteinReference> +<celldesigner:name>RAP1A</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="DRD1" id="s_id_sa11696" metaid="s_id_sa11696" initialAmount="0.0" charge="0" compartment="s_id_ca169"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: DRD1 +Name: dopamine receptor D1 +HGNC_ID: 3020 +EntrezGene_ID: 1812 +RefSeq_ID: NM_000794 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11707</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11696</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>DRD1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11707"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002211"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:DRD1"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P05556"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_000794"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:ITGB1"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:1812"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:3688"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000184845"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:6153"/> +<rdf:li rdf:resource="urn:miriam:hgnc:3020"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000150093"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P21728"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> </species> -<species metaid="s_id_csa1916" id="s_id_csa1916" name="Calmodulin" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>Calmodulin</celldesigner:name> +<species name="degraded_space_CTNNB1" id="s_id_sa11740" metaid="s_id_sa11740" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>DEGRADED</celldesigner:class> +<celldesigner:name>degraded_space_CTNNB1</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5869"/> -<celldesigner:catalyzed reaction="re5938"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> </annotation> </species> -<species metaid="s_id_sa11703" id="s_id_sa11703" name="cAMP" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: 3',5'-cyclic AMP -Synonyms: 3', 5'-Cyclic AMP, adenosine 3', 5'-cyclic monophosphate, Adenosine 3', 5'-cyclic phosphate, Adenosine 3', 5'-phosphate, ADENOSINE-3', 5'-CYCLIC-MONOPHOSPHATE, cAMP, Cyclic adenylic acid, Cyclic AMP, Recon metabolite: camp -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -<a href="http://vmh.uni.lu/#metabolite/camp">camp</a> -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> -<celldesigner:name>cAMP</celldesigner:name> +<species name="Calcineurin" id="s_id_csa1904" metaid="s_id_csa1904" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>Calcineurin</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5789"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11703"> -<bqbiol:is> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A17489"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0004723"/> </rdf:Bag> -</bqbiol:is> +</bqbiol:isEncodedBy> +<bqbiol:isEncodedBy> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:mesh:D019703"/> +</rdf:Bag> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="AHCYL:ITPR3" id="s_id_csa1889" metaid="s_id_csa1889" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>AHCYL:ITPR3</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="UPS" id="s_id_sa11719" metaid="s_id_sa11719" initialAmount="0.0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: proteasome complex +SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 0 + +A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>UPS</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqmodel:isDescribedBy> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0000502"/> +</rdf:Bag> +</bqmodel:isDescribedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="cofilin" id="s_id_csa1899" metaid="s_id_csa1899" initialAmount="0.0" charge="0" compartment="s_id_ca169"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>cofilin</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="AMP" id="s_id_sa11844" metaid="s_id_sa11844" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>AMP</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11791" id="s_id_sa11791" name="serotonin" compartment="default" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: serotonin -Synonyms: 3-(2-Aminoethyl)-1H-indol-5-ol, 3-(2-Aminoethyl)-1H-indol-5-ol, 5-HT, 5-Hydroxytryptamine, Enteramine, Serotonin, SEROTONIN, serotonine, thrombocytin, thrombotonin +</species> +<species name="UPS" id="s_id_sa11732" metaid="s_id_sa11732" initialAmount="0.0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: proteasome complex SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> -<celldesigner:name>serotonin</celldesigner:name> + +A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>UPS</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11791"> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqmodel:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A28790"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0000502"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqmodel:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1930" id="s_id_csa1930" name="TF_space_ELK1" compartment="s_id_ca182" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>TF_space_ELK1</celldesigner:name> +</species> +<species name="PKA" id="s_id_csa1901" metaid="s_id_csa1901" initialAmount="0.0" compartment="s_id_ca168"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: cAMP-dependent protein kinase complex +SemanticZoomLevelVisibility: 6 +TransparencyZoomLevelVisibility: 7 + +An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>PKA</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005952"/> +</rdf:Bag> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> </annotation> -</species><species metaid="s_id_csa1888" id="s_id_csa1888" name="LRRK2:PKAR2B:PKAC" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>LRRK2:PKAR2B:PKAC</celldesigner:name> +</species> +<species name="RASGRF1" id="s_id_sa11822" metaid="s_id_sa11822" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11822</celldesigner:proteinReference> +<celldesigner:name>RASGRF1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> </annotation> -</species><species metaid="s_id_sa11748" id="s_id_sa11748" name="EEF2K" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: EEF2K -Name: eukaryotic elongation factor 2 kinase -Synonyms: eEF-2K -HGNC_ID: 24615 -EntrezGene_ID: 29904 -RefSeq_ID: NM_013302 -SemanticZoomLevelVisibility: 5 +</species> +<species name="AHCYL1:ITPR3" id="s_id_csa1895" metaid="s_id_csa1895" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>AHCYL1:ITPR3</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="PENK" id="s_id_sa11858" metaid="s_id_sa11858" initialAmount="0.0" compartment="default"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11858</celldesigner:proteinReference> +<celldesigner:name>PENK</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="LRRK2" id="s_id_sa11718" metaid="s_id_sa11718" initialAmount="0.0" compartment="s_id_ca168"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: LRRK2 +Name: leucine rich repeat kinase 2 +Previous Symbols: PARK8 +Synonyms: DKFZp434H2111, FLJ45829, RIPK7, ROCO2 +HGNC_ID: 18618 +EntrezGene_ID: 120892 +RefSeq_ID: XM_058513 +SemanticZoomLevelVisibility: 6 TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11748</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11718</celldesigner:proteinReference> <celldesigner:state> <celldesigner:listOfModifications> -<celldesigner:modification residue="rs1" state="phosphorylated"/> -<celldesigner:modification residue="rs2" state="ubiquitinated"/> </celldesigner:listOfModifications> </celldesigner:state> +<celldesigner:name>LRRK2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11748"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:24615"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:120892"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_013302"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q5S007"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:EEF2K"/> +<rdf:li rdf:resource="urn:miriam:hgnc:18618"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:O00418"/> +<rdf:li rdf:resource="urn:miriam:refseq:XM_058513"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000103319"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000188906"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:29904"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:LRRK2"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11825" id="s_id_sa11825" name="DUSP1" compartment="s_id_ca182" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: DUSP1 -Name: dual specificity phosphatase 1 -Previous Symbols: PTPN10 -Synonyms: CL100, HVH1, MKP-1 -HGNC_ID: 3064 -EntrezGene_ID: 1843 -RefSeq_ID: NM_004417 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 +</species> +<species name="AMPA_space_receptor" id="s_id_csa1907" metaid="s_id_csa1907" initialAmount="0.0" charge="0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: AMPA glutamate receptor complex +SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 3 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>RNA</celldesigner:class> -<celldesigner:rnaReference>r_s_id_sa11825</celldesigner:rnaReference> + +An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>AMPA_space_receptor</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11825"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1843"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_004417"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P28562"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0032281"/> </rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="L_minus_glutamate" id="s_id_sa11872" metaid="s_id_sa11872" initialAmount="0.0" charge="0" compartment="default"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: L-glutamic acid +Synonyms: (S)-2-aminopentanedioic acid, (S)-glutamic acid, acide glutamique, acido glutamico, acidum glutamicum, E, Glu, Glutamate, GLUTAMIC ACID, glutamic acid, L-Glu, L-Glutamic acid, L-Glutaminic acid, L-Glutaminsaeure, Recon metabolite: glu_L +Reactome_ID: REACT_13119.1 +SemanticZoomLevelVisibility: 3 +TransparencyZoomLevelVisibility: 0 +Charge: 0 + +VMH database: <a href="http://vmh.uni.lu/#metabolite/glu_L">glu_L</a></body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>L_minus_glutamate</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:is> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:3064"/> +<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A16015"/> </rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</bqbiol:is> +<bqbiol:hasVersion> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:DUSP1"/> +<rdf:li rdf:resource="urn:miriam:reactome:REACT_13119.1"/> </rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</bqbiol:hasVersion> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="inclusion" id="s_id_csa1902" metaid="s_id_csa1902" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>inclusion</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="filamentous_space_actin" id="s_id_csa1898" metaid="s_id_csa1898" initialAmount="0.0" charge="0" compartment="s_id_ca169"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: filamentous actin +SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 7 +Charge: 0 + +A two-stranded helical polymer of the protein actin.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>filamentous_space_actin</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000120129"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0031941"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11786" id="s_id_sa11786" name="PPP1R1B" compartment="s_id_ca182" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PPP1R1B -Name: protein phosphatase 1 regulatory inhibitor subunit 1B -Synonyms: DARPP-32, FLJ20940 -HGNC_ID: 9287 -EntrezGene_ID: 84152 -RefSeq_ID: NM_032192 -SemanticZoomLevelVisibility: 5 +</species> +<species name="LRRK2" id="s_id_sa11726" metaid="s_id_sa11726" initialAmount="0.0" charge="0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: LRRK2 +Name: leucine rich repeat kinase 2 +Previous Symbols: PARK8 +Synonyms: DKFZp434H2111, FLJ45829, RIPK7, ROCO2 +HGNC_ID: 18618 +EntrezGene_ID: 120892 +RefSeq_ID: XM_058513 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11786</celldesigner:proteinReference> +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11726</celldesigner:proteinReference> <celldesigner:state> <celldesigner:listOfModifications> -<celldesigner:modification residue="rs2" state="phosphorylated"/> </celldesigner:listOfModifications> </celldesigner:state> +<celldesigner:name>LRRK2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11786"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_032192"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:120892"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000131771"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q5S007"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q9UD71"/> +<rdf:li rdf:resource="urn:miriam:hgnc:18618"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PPP1R1B"/> +<rdf:li rdf:resource="urn:miriam:refseq:XM_058513"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9287"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000188906"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:84152"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:LRRK2"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11705" id="s_id_sa11705" name="protein_space_translation" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: regulation of cytoplasmic translational elongation -SemanticZoomLevelVisibility: 5 +</species> +<species name="protein_space_translation" id="s_id_sa11705" metaid="s_id_sa11705" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: regulation of cytoplasmic translational elongation +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 Charge: 0 -Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PHENOTYPE</celldesigner:class> + +Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> <celldesigner:name>protein_space_translation</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11705"> +<rdf:Description rdf:about="#"> <bqbiol:isEncodedBy> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A1900247"/> @@ -10418,1118 +6621,741 @@ Any process that modulates the frequency, rate or extent of cytoplasmic translat </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1943" id="s_id_csa1943" name="PP2A" compartment="s_id_ca188" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>PP2A</celldesigner:name> +</species> +<species name="K_plus_" id="s_id_sa11721" metaid="s_id_sa11721" initialAmount="0.0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>ION</celldesigner:class> +<celldesigner:name>K_plus_</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> </annotation> -</species><species metaid="s_id_sa11700" id="s_id_sa11700" name="NTRK2" compartment="s_id_ca188" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: NTRK2 -Name: neurotrophic receptor tyrosine kinase 2 -Synonyms: TRKB -HGNC_ID: 8032 -EntrezGene_ID: 4915 -RefSeq_ID: NM_001007097, XM_005252001 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11700</celldesigner:proteinReference> +</species> +<species name="CTNNB1" id="s_id_sa11720" metaid="s_id_sa11720" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: CTNNB1 +Name: catenin beta 1 +Previous Symbols: CTNNB +Synonyms: armadillo, beta-catenin +HGNC_ID: 2514 +EntrezGene_ID: 1499 +RefSeq_ID: NM_001098210 +SemanticZoomLevelVisibility: 3 +TransparencyZoomLevelVisibility: 0 +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11720</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>CTNNB1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11700"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q16620"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001007097"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CTNNB1"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:XM_005252001"/> +<rdf:li rdf:resource="urn:miriam:hgnc:2514"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:4915"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_001098210"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:8032"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000168036"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:NTRK2"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P35222"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000148053"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:1499"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11743" id="s_id_sa11743" name="L_minus_glutamate" compartment="default" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: L-glutamic acid -Synonyms: (S)-2-aminopentanedioic acid, (S)-glutamic acid, acide glutamique, acido glutamico, acidum glutamicum, E, Glu, Glutamate, GLUTAMIC ACID, glutamic acid, L-Glu, L-Glutamic acid, L-Glutaminic acid, L-Glutaminsaeure, Recon metabolite: glu_L -Reactome_ID: REACT_13119.1 -SemanticZoomLevelVisibility: 3 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -<a href="http://vmh.uni.lu/#metabolite/glu_L">glu_L</a> -</body> -</html> -</notes><annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> -<celldesigner:name>L_minus_glutamate</celldesigner:name> -</celldesigner:speciesIdentity> -</celldesigner:extension> -<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11743"> -<bqbiol:is> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A16015"/> -</rdf:Bag> -</bqbiol:is> -<bqbiol:hasVersion> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:reactome:REACT_13119.1"/> -</rdf:Bag> -</bqbiol:hasVersion> -</rdf:Description> -</rdf:RDF> -</annotation> -</species><species metaid="s_id_sa11832" id="s_id_sa11832" name="acetylcholine" compartment="default" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: acetylcholine -Synonyms: Acetylcholine, ACETYLCHOLINE, acetylcholine, ACh, Azetylcholin, choline acetate, O-Acetylcholine -SemanticZoomLevelVisibility: 3 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> -<celldesigner:name>acetylcholine</celldesigner:name> +</species> +<species name="CHRM4" id="s_id_sa11831" metaid="s_id_sa11831" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11831</celldesigner:proteinReference> +<celldesigner:name>CHRM4</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11832"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A15355"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1898" id="s_id_csa1898" name="filamentous_space_actin" compartment="s_id_ca169" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: filamentous actin -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 7 -Charge: 0 -A two-stranded helical polymer of the protein actin. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> +</species> +<species name="PKA_space_catalytic_space_subunit" id="s_id_csa1915" metaid="s_id_csa1915" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>PKA_space_catalytic_space_subunit</celldesigner:name> <celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>filamentous_space_actin</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1898"> +<rdf:Description rdf:about="#"> <bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0031941"/> +<rdf:li rdf:resource="urn:miriam:ec-code:2.7.11.11"/> </rdf:Bag> </bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1937" id="s_id_csa1937" name="CaMKII" compartment="s_id_ca188" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: calcium- and calmodulin-dependent protein kinase complex -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 7 -An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>CaMKII</celldesigner:name> +</species> +<species name="ARPP21" id="s_id_sa11841" metaid="s_id_sa11841" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11841</celldesigner:proteinReference> <celldesigner:state> -<celldesigner:listOfStructuralStates> -<celldesigner:structuralState structuralState="phosphorylated"/> -</celldesigner:listOfStructuralStates> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> </celldesigner:state> +<celldesigner:name>ARPP21</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5803"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1937"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005954"/> -</rdf:Bag> -</bqbiol:isEncodedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1907" id="s_id_csa1907" name="AMPA_space_receptor" compartment="s_id_ca188" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: AMPA glutamate receptor complex -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 3 +</species> +<species name="dendritic_space_spine_space_development" id="s_id_sa11725" metaid="s_id_sa11725" initialAmount="0.0" charge="0" compartment="s_id_ca169"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: dendritic spine development +SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 0 Charge: 0 -An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>AMPA_space_receptor</celldesigner:name> + +The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>dendritic_space_spine_space_development</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5851"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1907"> -<bqbiol:isEncodedBy> +<rdf:Description rdf:about="#"> +<bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0032281"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0060996"/> </rdf:Bag> -</bqbiol:isEncodedBy> +</bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11730" id="s_id_sa11730" name="PRKAR2B" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PRKAR2B -Name: protein kinase cAMP-dependent type II regulatory subunit beta -Previous Symbols: PRKAR2 -HGNC_ID: 9392 -EntrezGene_ID: 5577 -RefSeq_ID: NM_002736 -SemanticZoomLevelVisibility: 5 +</species> +<species name="BTRC" id="s_id_sa11697" metaid="s_id_sa11697" initialAmount="0.0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: BTRC +Name: beta-transducin repeat containing E3 ubiquitin protein ligase +Synonyms: FBXW1A, Fwd1, bTrCP, bTrCP1, beta-TrCP1, betaTrCP +HGNC_ID: 1144 +EntrezGene_ID: 8945 +RefSeq_ID: NM_033637 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11730</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11697</celldesigner:proteinReference> +<celldesigner:name>BTRC</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11730"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9392"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000166167"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P31323"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q9Y297"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000005249"/> +<rdf:li rdf:resource="urn:miriam:hgnc:1144"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PRKAR2B"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:BTRC"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002736"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:8945"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5577"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_033637"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11784" id="s_id_sa11784" name="PTPN5" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PTPN5 -Name: protein tyrosine phosphatase, non-receptor type 5 -Synonyms: PTPSTEP, STEP, STEP61 -HGNC_ID: 9657 -EntrezGene_ID: 84867 -RefSeq_ID: NM_001039970 -SemanticZoomLevelVisibility: 5 +</species> +<species name="VIM" id="s_id_sa11737" metaid="s_id_sa11737" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: VIM +Name: vimentin +HGNC_ID: 12692 +EntrezGene_ID: 7431 +RefSeq_ID: NM_003380 +SemanticZoomLevelVisibility: 3 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11784</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11737</celldesigner:proteinReference> <celldesigner:state> <celldesigner:listOfModifications> -<celldesigner:modification residue="rs1" state="phosphorylated"/> </celldesigner:listOfModifications> </celldesigner:state> +<celldesigner:name>VIM</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11784"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9657"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:7431"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P54829"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_003380"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PTPN5"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000026025"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:84867"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P08670"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001039970"/> +<rdf:li rdf:resource="urn:miriam:hgnc:12692"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000110786"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:VIM"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11754" id="s_id_sa11754" name="RANBP9" compartment="s_id_ca188" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: RANBP9 -Name: RAN binding protein 9 -Synonyms: RanBPM -HGNC_ID: 13727 -EntrezGene_ID: 10048 -RefSeq_ID: NM_005493 -SemanticZoomLevelVisibility: 5 +</species> +<species name="PRKCD" id="s_id_sa11723" metaid="s_id_sa11723" initialAmount="0.0" charge="0" compartment="s_id_ca169"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: PRKCD +Name: protein kinase C delta +HGNC_ID: 9399 +EntrezGene_ID: 5580 +RefSeq_ID: NM_001316327 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11754</celldesigner:proteinReference> +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11723</celldesigner:proteinReference> +<celldesigner:name>PRKCD</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11754"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:13727"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PRKCD"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000010017"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q05655"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q96S59"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:5580"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_005493"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000163932"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RANBP9"/> +<rdf:li rdf:resource="urn:miriam:hgnc:9399"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:10048"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_001316327"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11783" id="s_id_sa11783" name="PTPN5" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PTPN5 -Name: protein tyrosine phosphatase, non-receptor type 5 -Synonyms: PTPSTEP, STEP, STEP61 -HGNC_ID: 9657 -EntrezGene_ID: 84867 -RefSeq_ID: NM_001039970 -SemanticZoomLevelVisibility: 5 +</species> +<species name="PPP1R1B" id="s_id_sa11779" metaid="s_id_sa11779" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11779</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +<celldesigner:modification residue="rs2" state="phosphorylated"> </celldesigner:modification> +<celldesigner:modification residue="rs3" state="phosphorylated"> </celldesigner:modification> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>PPP1R1B</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="PP2C" id="s_id_sa11834" metaid="s_id_sa11834" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11834</celldesigner:proteinReference> +<celldesigner:name>PP2C</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:interpro:IPR015655"/> +</rdf:Bag> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="degraded_space_EEF2K" id="s_id_sa11756" metaid="s_id_sa11756" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>DEGRADED</celldesigner:class> +<celldesigner:name>degraded_space_EEF2K</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="Rap1_space_activating" id="s_id_csa1917" metaid="s_id_csa1917" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>Rap1_space_activating</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:interpro:IPR000331"/> +</rdf:Bag> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="NTRK2" id="s_id_sa11700" metaid="s_id_sa11700" initialAmount="0.0" charge="0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: NTRK2 +Name: neurotrophic receptor tyrosine kinase 2 +Synonyms: TRKB +HGNC_ID: 8032 +EntrezGene_ID: 4915 +RefSeq_ID: XM_005252001 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11783</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11700</celldesigner:proteinReference> +<celldesigner:name>NTRK2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11783"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9657"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q16620"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P54829"/> +<rdf:li rdf:resource="urn:miriam:refseq:XM_005252001"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PTPN5"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:4915"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:84867"/> +<rdf:li rdf:resource="urn:miriam:hgnc:8032"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001039970"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:NTRK2"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000110786"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000148053"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11789" id="s_id_sa11789" name="HTR4" compartment="s_id_ca188" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: HTR4 -Name: 5-hydroxytryptamine receptor 4 -Synonyms: 5-HT4 -HGNC_ID: 5299 -EntrezGene_ID: 3360 -RefSeq_ID: NM_000870 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11789</celldesigner:proteinReference> +</species> +<species name="long_minus_term_space_memory" id="s_id_sa11809" metaid="s_id_sa11809" initialAmount="0.0" charge="0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>long_minus_term_space_memory</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11789"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:HTR4"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_000870"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q13639"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:5299"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:3360"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000164270"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0007616"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11721" id="s_id_sa11721" name="K_plus_" compartment="s_id_ca188" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: potassium(1+) -Synonyms: K(+), K+, K(+), POTASSIUM ION -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>ION</celldesigner:class> -<celldesigner:name>K_plus_</celldesigner:name> +</species> +<species name="PP2A" id="s_id_csa1911" metaid="s_id_csa1911" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>PP2A</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11721"> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29103"/> +<rdf:li rdf:resource="urn:miriam:mesh:D054648"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11699" id="s_id_sa11699" name="dendrite_space_extension" compartment="s_id_ca168" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: dendrite extension +</species> +<species name="mitochondrial_space_motility" id="s_id_sa11729" metaid="s_id_sa11729" initialAmount="0.0" charge="0" compartment="s_id_ca168"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: mitochondrion transport along microtubule SemanticZoomLevelVisibility: 6 TransparencyZoomLevelVisibility: 0 Charge: 0 -Long distance growth of a single dendrite involved in cellular development. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PHENOTYPE</celldesigner:class> -<celldesigner:name>dendrite_space_extension</celldesigner:name> + +The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>mitochondrial_space_motility</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11699"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0097484"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0047497"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11790" id="s_id_sa11790" name="HTR6" compartment="s_id_ca188" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: HTR6 -Name: 5-hydroxytryptamine receptor 6 -Synonyms: 5-HT6, 5-HT6R -HGNC_ID: 5301 -EntrezGene_ID: 3362 -RefSeq_ID: NM_000871 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11790</celldesigner:proteinReference> +</species> +<species name="Ca2_plus_" id="s_id_sa11788" metaid="s_id_sa11788" initialAmount="0.0" compartment="s_id_ca169"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>ION</celldesigner:class> +<celldesigner:name>Ca2_plus_</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11790"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:5301"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:HTR6"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_000871"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P50406"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="synaptic_space_plasticity" id="s_id_sa11848" metaid="s_id_sa11848" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>synaptic_space_plasticity</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000158748"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0031915"/> </rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="small_minus_conductance_space_KCa_space_channels" id="s_id_csa1924" metaid="s_id_csa1924" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>small_minus_conductance_space_KCa_space_channels</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isPartOf> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:3362"/> +<rdf:li rdf:resource="urn:miriam:interpro:IPR015449"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isPartOf> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11716" id="s_id_sa11716" name="ITPR3" compartment="s_id_ca187" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: ITPR3 -Name: inositol 1,4,5-trisphosphate receptor type 3 -Synonyms: IP3R3 -HGNC_ID: 6182 -EntrezGene_ID: 3710 -RefSeq_ID: NM_002224 +</species> +<species name="ITPR2" id="s_id_sa11755" metaid="s_id_sa11755" initialAmount="0.0" charge="0" compartment="s_id_ca187"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: ITPR2 +Name: inositol 1,4,5-trisphosphate receptor type 2 +Synonyms: CFAP48, IP3R2 +HGNC_ID: 6181 +EntrezGene_ID: 3709 +RefSeq_ID: NM_002223 SemanticZoomLevelVisibility: 7 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11716</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11755</celldesigner:proteinReference> +<celldesigner:name>ITPR2</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5834"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11716"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002224"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_002223"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:ITPR3"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q14571"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q14573"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:ITPR2"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:6182"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:3709"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:3710"/> +<rdf:li rdf:resource="urn:miriam:hgnc:6181"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000096433"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000123104"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11799" id="s_id_sa11799" name="chromatin_space_organization" compartment="s_id_ca182" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PHENOTYPE</celldesigner:class> -<celldesigner:name>chromatin_space_organization</celldesigner:name> +</species> +<species name="PP2A" id="s_id_csa1943" metaid="s_id_csa1943" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>PP2A</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11799"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0006325"/> -</rdf:Bag> -</bqbiol:isEncodedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11821" id="s_id_sa11821" name="RASGRF1" compartment="s_id_ca188" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: RASGRF1 -Name: Ras protein specific guanine nucleotide releasing factor 1 -Previous Symbols: GRF1 -Synonyms: CDC25, CDC25L, GNRP, GRF55, H-GRF55, PP13187 -HGNC_ID: 9875 -EntrezGene_ID: 5923 -RefSeq_ID: NM_002891 -Pubmed_ID: 16467520 -SemanticZoomLevelVisibility: 5 +</species> +<species name="RGS4" id="s_id_sa11702" metaid="s_id_sa11702" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: RGS4 +Name: regulator of G-protein signaling 4 +Previous Symbols: SCZD9 +HGNC_ID: 10000 +EntrezGene_ID: 5999 +RefSeq_ID: NM_005613 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11821</celldesigner:proteinReference> +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11702</celldesigner:proteinReference> +<celldesigner:name>RGS4</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11821"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000058335"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9875"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_005613"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5923"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:5999"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002891"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P49798"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:pubmed:16467520"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000117152"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q13972"/> +<rdf:li rdf:resource="urn:miriam:hgnc:10000"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RASGRF1"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RGS4"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1919" id="s_id_csa1919" name="CaMKII" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: calcium- and calmodulin-dependent protein kinase complex -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 7 -Charge: 0 -An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>CaMKII</celldesigner:name> +</species> +<species name="PDYN" id="s_id_sa11827" metaid="s_id_sa11827" initialAmount="0.0" charge="0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>RNA</celldesigner:class> +<celldesigner:rnaReference>r_s_id_sa11827</celldesigner:rnaReference> +<celldesigner:name>PDYN</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5938"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1919"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005954"/> -</rdf:Bag> -</bqbiol:isEncodedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1914" id="s_id_csa1914" name="Calcineurin" compartment="s_id_ca173" initialAmount="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>Calcineurin</celldesigner:name> +</species> +<species name="GRM1" id="s_id_sa11766" metaid="s_id_sa11766" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11766</celldesigner:proteinReference> +<celldesigner:name>GRM1</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5855"/> -<celldesigner:catalyzed reaction="re5879"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1914"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0004723"/> -</rdf:Bag> -</bqbiol:isEncodedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11695" id="s_id_sa11695" name="MAP2" compartment="s_id_ca168" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: MAP2 -Name: microtubule associated protein 2 -Synonyms: MAP2A, MAP2B, MAP2C -HGNC_ID: 6839 -EntrezGene_ID: 4133 -RefSeq_ID: NM_001039538 -SemanticZoomLevelVisibility: 6 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11695</celldesigner:proteinReference> +</species> +<species name="FOS" id="s_id_sa11824" metaid="s_id_sa11824" initialAmount="0.0" charge="0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>RNA</celldesigner:class> +<celldesigner:rnaReference>r_s_id_sa11824</celldesigner:rnaReference> +<celldesigner:name>FOS</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5826"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11695"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001039538"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P11137"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000078018"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:MAP2"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:4133"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:6839"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11844" id="s_id_sa11844" name="AMP" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: adenosine 5'-monophosphate -Synonyms: 5'-Adenosine monophosphate, 5'-Adenylic acid, 5'-AMP, 5'-O-phosphonoadenosine, adenosine 5'-(dihydrogen phosphate), Adenosine 5'-monophosphate, Adenosine 5'-phosphate, ADENOSINE MONOPHOSPHATE, adenosine phosphate, adenosine phosphate, Adenosine-5'-monophosphoric acid, adenosine-5'P, adenosini phosphas, Adenylate, Adenylic acid, Ado5'P, AMP, fosfato de adenosina, pA, PAdo, phosphate d'adenosine -SemanticZoomLevelVisibility: 5 +</species> +<species name="PIP2" id="s_id_sa11759" metaid="s_id_sa11759" initialAmount="0.0" compartment="s_id_ca188"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate +Synonyms: 1, 2-Diacyl-sn-glycero-3-phospho-(1'-myo-inositol-4', 5'-bisphosphate), 1-Phosphatidyl-1D-myo-inositol 4, 5-bisphosphate, 1-Phosphatidyl-1D-myo-inositol 4, 5-bisphosphate, 1-Phosphatidyl-D-myo-inositol 4, 5-bisphosphate, 1-Phosphatidyl-D-myo-inositol 4, 5-bisphosphate, Phosphatidyl-myo-inositol 4, 5-bisphosphate, Phosphatidyl-myo-inositol 4, 5-bisphosphate, Phosphatidylinositol-4, 5-bisphosphate, Phosphatidylinositol-4, 5-bisphosphate, PIP2, PIPP, PtsIns(4, 5)P2, PtsIns-4, 5-P2 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> -<celldesigner:name>AMP</celldesigner:name> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>innerSurface</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>PIP2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11844"> -<bqbiol:is> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A16027"/> +<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A18348"/> </rdf:Bag> -</bqbiol:is> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11717" id="s_id_sa11717" name="postsynaptic_space_response" compartment="s_id_ca168" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: excitatory postsynaptic potential -SemanticZoomLevelVisibility: 6 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PHENOTYPE</celldesigner:class> -<celldesigner:name>postsynaptic_space_response</celldesigner:name> +</species> +<species name="PKA_space_catalytic_space_subunit" id="s_id_csa1892" metaid="s_id_csa1892" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>PKA_space_catalytic_space_subunit</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11717"> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0060079"/> +<rdf:li rdf:resource="urn:miriam:ec-code:2.7.11.11"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1920" id="s_id_csa1920" name="TF_space_CREB" compartment="s_id_ca182" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>TF_space_CREB</celldesigner:name> +</species> +<species name="CNR1" id="s_id_sa11793" metaid="s_id_sa11793" initialAmount="0.0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11793</celldesigner:proteinReference> +<celldesigner:name>CNR1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> </annotation> -</species><species metaid="s_id_sa11712" id="s_id_sa11712" name="PINK1" compartment="s_id_ca168" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PINK1 -Name: PTEN induced putative kinase 1 -Previous Symbols: PARK6 -HGNC_ID: 14581 -EntrezGene_ID: 65018 -RefSeq_ID: NM_032409 +</species> +<species name="GNAQ" id="s_id_sa11767" metaid="s_id_sa11767" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11767</celldesigner:proteinReference> +<celldesigner:name>GNAQ</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:interpro:IPR000654"/> +</rdf:Bag> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="ATP" id="s_id_sa11839" metaid="s_id_sa11839" initialAmount="0.0" charge="0" compartment="s_id_ca169"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: ATP +Synonyms: Adenosine 5'-triphosphate, Adenosine triphosphate, ADENOSINE-5'-TRIPHOSPHATE, Adephos, Adetol, Adynol, Atipi, ATP, Atriphos, Cardenosine, Fosfobion, Glucobasin, H4atp, Myotriphos, Triadenyl, Triphosphaden, Recon metabolite: atp SemanticZoomLevelVisibility: 6 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11712</celldesigner:proteinReference> + +VMH database: <a href="http://vmh.uni.lu/#metabolite/atp">atp</a></body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>ATP</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5827"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11712"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:65018"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q9BXM7"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:PINK1"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000158828"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_032409"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +<bqbiol:is> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:14581"/> +<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A15422"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:is> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11845" id="s_id_sa11845" name="PDEs" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> +</species> +<species name="PDEs" id="s_id_sa11845" metaid="s_id_sa11845" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> <celldesigner:proteinReference>p_s_id_sa11845</celldesigner:proteinReference> +<celldesigner:name>PDEs</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5954"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11845"> +<rdf:Description rdf:about="#"> <bqbiol:isEncodedBy> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:interpro:IPR023088"/> @@ -11538,3000 +7364,1039 @@ Charge: 0 </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1912" id="s_id_csa1912" name="calpain_minus_1" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>calpain_minus_1</celldesigner:name> +</species> +<species name="cofilin" id="s_id_csa1894" metaid="s_id_csa1894" initialAmount="0.0" charge="0" compartment="s_id_ca169"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>cofilin</celldesigner:name> +<celldesigner:hypothetical>true</celldesigner:hypothetical> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="TF_space_ELK1" id="s_id_csa1930" metaid="s_id_csa1930" initialAmount="0.0" charge="0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>TF_space_ELK1</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="HTR4" id="s_id_sa11789" metaid="s_id_sa11789" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11789</celldesigner:proteinReference> +<celldesigner:name>HTR4</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="GNAL" id="s_id_sa11741" metaid="s_id_sa11741" initialAmount="0.0" charge="0" compartment="s_id_ca169"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: GNAL +Name: G protein subunit alpha L +SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 0 +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11741</celldesigner:proteinReference> +<celldesigner:name>GNAL</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5861"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1912"> +<rdf:Description rdf:about="#"> <bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:interpro:IPR029643"/> +<rdf:li rdf:resource="urn:miriam:interpro:IPR000367"/> </rdf:Bag> </bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11702" id="s_id_sa11702" name="RGS4" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: RGS4 -Name: regulator of G-protein signaling 4 -Previous Symbols: SCZD9 -HGNC_ID: 10000 -EntrezGene_ID: 5999 -RefSeq_ID: NM_005613 -SemanticZoomLevelVisibility: 5 +</species> +<species name="dendrite_space_extension" id="s_id_sa11699" metaid="s_id_sa11699" initialAmount="0.0" charge="0" compartment="s_id_ca168"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Name: dendrite extension +SemanticZoomLevelVisibility: 6 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11702</celldesigner:proteinReference> + +Long distance growth of a single dendrite involved in cellular development.</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>dendrite_space_extension</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11702"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_005613"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5999"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P49798"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000117152"/> -</rdf:Bag> -</bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:10000"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0097484"/> </rdf:Bag> </bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="CaMKII" id="s_id_csa1919" metaid="s_id_csa1919" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>CaMKII</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RGS4"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005954"/> </rdf:Bag> -</bqbiol:isDescribedBy> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1894" id="s_id_csa1894" name="cofilin" compartment="s_id_ca169" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> +</species> +<species name="OPRM1" id="s_id_sa11792" metaid="s_id_sa11792" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11792</celldesigner:proteinReference> +<celldesigner:name>OPRM1</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="L_minus_type_space_calcium_space_channel_BR_Cav1.3_space_and_space_Cav1.2" id="s_id_csa1923" metaid="s_id_csa1923" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>outerSurface</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>L_minus_type_space_calcium_space_channel_BR_Cav1.3_space_and_space_Cav1.2</celldesigner:name> <celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>cofilin</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:interpro:IPR005446"/> +</rdf:Bag> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> </annotation> -</species><species metaid="s_id_csa1890" id="s_id_csa1890" name="Caspase_minus_8" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>Caspase_minus_8</celldesigner:name> +</species> +<species name="GNAS" id="s_id_sa11763" metaid="s_id_sa11763" initialAmount="0.0" charge="0" compartment="s_id_ca169"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: GNAS +Name: GNAS complex locus +Previous Symbols: GNAS1 +Synonyms: GNASXL, GPSA, NESP, NESP55, SCG6, SgVI +SemanticZoomLevelVisibility: 4 +TransparencyZoomLevelVisibility: 0 +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11763</celldesigner:proteinReference> +<celldesigner:name>GNAS</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5811"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:interpro:IPR000367"/> +</rdf:Bag> +</bqbiol:isEncodedBy> +</rdf:Description> +</rdf:RDF> </annotation> -</species><species metaid="s_id_csa1917" id="s_id_csa1917" name="Rap1_space_activating" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>Rap1_space_activating</celldesigner:name> +</species> +<species name="Calcineurin" id="s_id_csa1940" metaid="s_id_csa1940" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>Calcineurin</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1917"> +<rdf:Description rdf:about="#"> <bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:interpro:IPR000331"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0004723"/> +</rdf:Bag> +</bqbiol:isEncodedBy> +<bqbiol:isEncodedBy> +<rdf:Bag> +<rdf:li rdf:resource="urn:miriam:mesh:D019703"/> </rdf:Bag> </bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11781" id="s_id_sa11781" name="CSNK1A1" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: CSNK1A1 -Name: casein kinase 1 alpha 1 -Synonyms: CK1, CK1a, CK1alpha, CKIa, CKIalpha -HGNC_ID: 2451 -EntrezGene_ID: 1452 -RefSeq_ID: NM_001892 -SemanticZoomLevelVisibility: 5 +</species> +<species name="EEF2K" id="s_id_sa11748" metaid="s_id_sa11748" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: EEF2K +Name: eukaryotic elongation factor 2 kinase +Synonyms: eEF-2K +HGNC_ID: 24615 +EntrezGene_ID: 29904 +RefSeq_ID: NM_013302 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11781</celldesigner:proteinReference> +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11748</celldesigner:proteinReference> <celldesigner:state> <celldesigner:listOfModifications> -<celldesigner:modification residue="rs1" state="phosphorylated"/> +<celldesigner:modification residue="rs1" state="phosphorylated"> </celldesigner:modification> +<celldesigner:modification residue="rs2" state="ubiquitinated"> </celldesigner:modification> </celldesigner:listOfModifications> </celldesigner:state> +<celldesigner:name>EEF2K</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5942"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11781"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CSNK1A1"/> +<rdf:li rdf:resource="urn:miriam:hgnc:24615"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001892"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_013302"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:2451"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:EEF2K"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P48729"/> +<rdf:li rdf:resource="urn:miriam:uniprot:O00418"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:1452"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000103319"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000113712"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:29904"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11756" id="s_id_sa11756" name="degraded_space_EEF2K" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>DEGRADED</celldesigner:class> -<celldesigner:name>degraded_space_EEF2K</celldesigner:name> +</species> +<species name="CDK5" id="s_id_sa11774" metaid="s_id_sa11774" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11774</celldesigner:proteinReference> +<celldesigner:name>CDK5</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> </annotation> -</species><species metaid="s_id_sa11822" id="s_id_sa11822" name="RASGRF1" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: RASGRF1 -Name: Ras protein specific guanine nucleotide releasing factor 1 -Previous Symbols: GRF1 -Synonyms: CDC25, CDC25L, GNRP, GRF55, H-GRF55, PP13187 -HGNC_ID: 9875 -EntrezGene_ID: 5923 -RefSeq_ID: NM_002891 -Pubmed_ID: 16467520 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11822</celldesigner:proteinReference> +</species> +<species name="s3264" id="s_id_sa11758" metaid="s_id_sa11758" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>DEGRADED</celldesigner:class> +<celldesigner:name>s3264</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11822"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000058335"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> +<rdf:Description rdf:about="#"> +</rdf:Description> +</rdf:RDF> +</annotation> +</species> +<species name="MAP2" id="s_id_sa11695" metaid="s_id_sa11695" initialAmount="0.0" charge="0" compartment="s_id_ca168"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: MAP2 +Name: microtubule associated protein 2 +Synonyms: MAP2A, MAP2B, MAP2C +HGNC_ID: 6839 +EntrezGene_ID: 4133 +RefSeq_ID: NM_001039538 +SemanticZoomLevelVisibility: 6 +TransparencyZoomLevelVisibility: 0 +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11695</celldesigner:proteinReference> +<celldesigner:name>MAP2</celldesigner:name> +</celldesigner:speciesIdentity> +</celldesigner:extension> +<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> +<rdf:Description rdf:about="#"> +<bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:9875"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_001039538"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:5923"/> +<rdf:li rdf:resource="urn:miriam:uniprot:P11137"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_002891"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000078018"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:pubmed:16467520"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:MAP2"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q13972"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:4133"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RASGRF1"/> +<rdf:li rdf:resource="urn:miriam:hgnc:6839"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1913" id="s_id_csa1913" name="PP1" compartment="s_id_ca173" initialAmount="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>PP1</celldesigner:name> -</celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5867"/> -<celldesigner:catalyzed reaction="re5938"/> -</celldesigner:listOfCatalyzedReactions> -</celldesigner:extension> -</annotation> -</species><species metaid="s_id_csa1928" id="s_id_csa1928" name="PP1" compartment="s_id_ca182" initialAmount="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> +</species> +<species name="NMDA_space_receptor" id="s_id_csa1905" metaid="s_id_csa1905" initialAmount="0.0" charge="0" compartment="s_id_ca188"><annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>NMDA_space_receptor</celldesigner:name> <celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>PP1</celldesigner:name> -</celldesigner:speciesIdentity> -</celldesigner:extension> -</annotation> -</species><species metaid="s_id_sa11785" id="s_id_sa11785" name="MAPK_space_pathway" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: MAPK cascade -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PHENOTYPE</celldesigner:class> -<celldesigner:name>MAPK_space_pathway</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11785"> +<rdf:Description rdf:about="#"> <bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0000165"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0017146"/> </rdf:Bag> </bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11724" id="s_id_sa11724" name="Ca2_plus_" compartment="s_id_ca187" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: calcium(2+) -Synonyms: Ca(2+), Ca2+, Ca(2+), CALCIUM ION, calcium, doubly charged positive ion -SemanticZoomLevelVisibility: 7 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>ION</celldesigner:class> -<celldesigner:name>Ca2_plus_</celldesigner:name> -</celldesigner:speciesIdentity> -</celldesigner:extension> -<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11724"> -<bqbiol:is> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/> -</rdf:Bag> -</bqbiol:is> -</rdf:Description> -</rdf:RDF> -</annotation> -</species><species metaid="s_id_csa1906" id="s_id_csa1906" name="ROCK" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>ROCK</celldesigner:name> +</species> +<species name="calpain_minus_1" id="s_id_csa1912" metaid="s_id_csa1912" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> +<celldesigner:name>calpain_minus_1</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5848"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1906"> -<bqbiol:isPartOf> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:interpro:IPR020684"/> +<rdf:li rdf:resource="urn:miriam:interpro:IPR029643"/> </rdf:Bag> -</bqbiol:isPartOf> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1924" id="s_id_csa1924" name="small_minus_conductance_space_KCa_space_channels" compartment="s_id_ca188" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:hypothetical>true</celldesigner:hypothetical> -<celldesigner:name>small_minus_conductance_space_KCa_space_channels</celldesigner:name> +</species> +<species name="MAPK_space_pathway" id="s_id_sa11785" metaid="s_id_sa11785" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PHENOTYPE</celldesigner:class> +<celldesigner:name>MAPK_space_pathway</celldesigner:name> </celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5831"/> -</celldesigner:listOfCatalyzedReactions> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1924"> -<bqbiol:isPartOf> +<rdf:Description rdf:about="#"> +<bqbiol:isEncodedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:interpro:IPR015449"/> +<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0000165"/> </rdf:Bag> -</bqbiol:isPartOf> +</bqbiol:isEncodedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11769" id="s_id_sa11769" name="Ca2_plus_" compartment="default" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: calcium(2+) -Synonyms: Ca(2+), Ca2+, Ca(2+), CALCIUM ION, calcium, doubly charged positive ion -SemanticZoomLevelVisibility: 3 -TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>ION</celldesigner:class> -<celldesigner:name>Ca2_plus_</celldesigner:name> +</species> +<species name="DUSP1" id="s_id_sa11825" metaid="s_id_sa11825" initialAmount="0.0" charge="0" compartment="s_id_ca182"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>RNA</celldesigner:class> +<celldesigner:rnaReference>r_s_id_sa11825</celldesigner:rnaReference> +<celldesigner:name>DUSP1</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11769"> -<bqbiol:is> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/> -</rdf:Bag> -</bqbiol:is> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1936" id="s_id_csa1936" name="CaMKII" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: calcium- and calmodulin-dependent protein kinase complex -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 7 -An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>CaMKII</celldesigner:name> +</species> +<species name="CaMKII" id="s_id_csa1936" metaid="s_id_csa1936" initialAmount="0.0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>COMPLEX</celldesigner:class> <celldesigner:state> <celldesigner:listOfStructuralStates> -<celldesigner:structuralState structuralState="phosphorylated"/> -</celldesigner:listOfStructuralStates> +<celldesigner:structuralState structuralState="phosphorylated">phosphorylated</celldesigner:structuralState></celldesigner:listOfStructuralStates> </celldesigner:state> +<celldesigner:name>CaMKII</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1936"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005954"/> -</rdf:Bag> -</bqbiol:isEncodedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11841" id="s_id_sa11841" name="ARPP21" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: ARPP21 -Name: cAMP regulated phosphoprotein 21 -Synonyms: ARPP-21, R3HDM3, TARPP -HGNC_ID: 16968 -EntrezGene_ID: 10777 -RefSeq_ID: NM_198399 -SemanticZoomLevelVisibility: 5 +</species> +<species name="RASGRP2" id="s_id_sa11787" metaid="s_id_sa11787" initialAmount="0.0" charge="0" compartment="s_id_ca173"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: RASGRP2 +Name: RAS guanyl releasing protein 2 +Synonyms: CALDAG-GEFI +HGNC_ID: 9879 +EntrezGene_ID: 10235 +RefSeq_ID: NM_153819 +SemanticZoomLevelVisibility: 4 TransparencyZoomLevelVisibility: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11841</celldesigner:proteinReference> +Charge: 0 + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11787</celldesigner:proteinReference> +<celldesigner:state> +<celldesigner:listOfModifications> +</celldesigner:listOfModifications> +</celldesigner:state> +<celldesigner:name>RASGRP2</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11841"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:ARPP21"/> +<rdf:li rdf:resource="urn:miriam:refseq:NM_153819"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q9UBL0"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:RASGRP2"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000172995"/> +<rdf:li rdf:resource="urn:miriam:hgnc:9879"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:10777"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q7LDG7"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:16968"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000068831"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_198399"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:10235"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1904" id="s_id_csa1904" name="Calcineurin" compartment="s_id_ca173" initialAmount="0" charge="0"> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>Calcineurin</celldesigner:name> -</celldesigner:speciesIdentity> -</celldesigner:extension> -<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1904"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0004723"/> -</rdf:Bag> -</bqbiol:isEncodedBy> -</rdf:Description> -</rdf:RDF> -</annotation> -</species><species metaid="s_id_sa11711" id="s_id_sa11711" name="EEF2K" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: EEF2K -Name: eukaryotic elongation factor 2 kinase -Synonyms: eEF-2K -HGNC_ID: 24615 -EntrezGene_ID: 29904 -RefSeq_ID: NM_013302 -SemanticZoomLevelVisibility: 5 +</species> +<species name="LRRK2" id="s_id_sa11710" metaid="s_id_sa11710" initialAmount="0.0" charge="0" compartment="s_id_ca168"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: LRRK2 +Name: leucine rich repeat kinase 2 +Previous Symbols: PARK8 +Synonyms: DKFZp434H2111, FLJ45829, RIPK7, ROCO2 +HGNC_ID: 18618 +EntrezGene_ID: 120892 +RefSeq_ID: XM_058513 +SemanticZoomLevelVisibility: 6 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> 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xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11711"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:24615"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:120892"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_013302"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q5S007"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:EEF2K"/> +<rdf:li rdf:resource="urn:miriam:hgnc:18618"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:O00418"/> +<rdf:li rdf:resource="urn:miriam:refseq:XM_058513"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000103319"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000188906"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:29904"/> +<rdf:li rdf:resource="urn:miriam:hgnc.symbol:LRRK2"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11732" id="s_id_sa11732" name="UPS" compartment="s_id_ca173" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: proteasome complex -SemanticZoomLevelVisibility: 3 -TransparencyZoomLevelVisibility: 0 -A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PHENOTYPE</celldesigner:class> -<celldesigner:name>UPS</celldesigner:name> -</celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5812"/> -</celldesigner:listOfCatalyzedReactions> -</celldesigner:extension> -<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11732"> -<bqmodel:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0000502"/> -</rdf:Bag> -</bqmodel:isDescribedBy> -</rdf:Description> -</rdf:RDF> -</annotation> -</species><species metaid="s_id_sa11848" id="s_id_sa11848" name="synaptic_space_plasticity" compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: positive regulation of synaptic plasticity -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PHENOTYPE</celldesigner:class> -<celldesigner:name>synaptic_space_plasticity</celldesigner:name> -</celldesigner:speciesIdentity> -</celldesigner:extension> -<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11848"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0031915"/> -</rdf:Bag> -</bqbiol:isEncodedBy> -</rdf:Description> -</rdf:RDF> -</annotation> -</species><species metaid="s_id_sa11840" id="s_id_sa11840" name="cAMP" compartment="s_id_ca169" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: 3',5'-cyclic AMP -Synonyms: 3', 5'-Cyclic AMP, adenosine 3', 5'-cyclic monophosphate, Adenosine 3', 5'-cyclic phosphate, Adenosine 3', 5'-phosphate, ADENOSINE-3', 5'-CYCLIC-MONOPHOSPHATE, cAMP, Cyclic adenylic acid, Cyclic AMP, Recon metabolite: camp -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -<a href="http://vmh.uni.lu/#metabolite/camp">camp</a> -</body> -</html> -</notes><annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> -<celldesigner:name>cAMP</celldesigner:name> -</celldesigner:speciesIdentity> -</celldesigner:extension> -<rdf:RDF 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metaid="s_id_sa11716" initialAmount="0.0" charge="0" compartment="s_id_ca187"><notes><html xmlns="http://www.w3.org/1999/xhtml"><head><title/></head><body>Symbol: ITPR3 +Name: inositol 1,4,5-trisphosphate receptor type 3 +Synonyms: IP3R3 +HGNC_ID: 6182 +EntrezGene_ID: 3710 +RefSeq_ID: NM_002224 +SemanticZoomLevelVisibility: 7 TransparencyZoomLevelVisibility: 0 Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11763</celldesigner:proteinReference> + +</body></html></notes> +<annotation><celldesigner:extension><celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>PROTEIN</celldesigner:class> +<celldesigner:proteinReference>p_s_id_sa11716</celldesigner:proteinReference> 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<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000087460"/> +<rdf:li rdf:resource="urn:miriam:uniprot:Q14573"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:P63092"/> +<rdf:li rdf:resource="urn:miriam:hgnc:6182"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_000516"/> +<rdf:li rdf:resource="urn:miriam:ncbigene:3710"/> </rdf:Bag> </bqbiol:isDescribedBy> <bqbiol:isDescribedBy> <rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:O95467"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:GNAS"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:interpro:IPR000367"/> -</rdf:Bag> -</bqbiol:isEncodedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:4392"/> +<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000096433"/> </rdf:Bag> </bqbiol:isDescribedBy> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_sa11736" id="s_id_sa11736" name="IP3_space_" compartment="s_id_ca188" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: 1D-myo-inositol 1,4,5-trisphosphate -Synonyms: 1, 4, 5-Insp3, 1D-myo-Inositol 1, 4, 5-trisphosphate, D-myo-Inositol 1, 4, 5-trisphosphate, D-MYO-INOSITOL-1, 4, 5-TRIPHOSPHATE, Inositol 1, 4, 5-trisphosphate, Ins(1, 4, 5)P3, InsP3, IP3, Recon metabolite: mi145p -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -<a href="http://vmh.uni.lu/#metabolite/mi145p">mi145p</a> -</body> -</html> -</notes><annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> -<celldesigner:name>IP3_space_</celldesigner:name> +</species> +<species name="s391" id="s_id_sa11775" metaid="s_id_sa11775" initialAmount="0.0" charge="0" compartment="s_id_ca173"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>DEGRADED</celldesigner:class> +<celldesigner:name>s391</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_sa11736"> -<bqbiol:is> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A16595"/> -</rdf:Bag> -</bqbiol:is> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1901" id="s_id_csa1901" name="PKA" compartment="s_id_ca168" initialAmount="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: cAMP-dependent protein kinase complex -SemanticZoomLevelVisibility: 6 -TransparencyZoomLevelVisibility: 7 -An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer. -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>COMPLEX</celldesigner:class> -<celldesigner:name>PKA</celldesigner:name> +</species> +<species name="serotonin" id="s_id_sa11791" metaid="s_id_sa11791" initialAmount="0.0" compartment="default"><annotation><celldesigner:extension><celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment><celldesigner:speciesIdentity><celldesigner:class>SIMPLE_MOLECULE</celldesigner:class> +<celldesigner:name>serotonin</celldesigner:name> </celldesigner:speciesIdentity> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#s_id_csa1901"> -<bqbiol:isEncodedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005952"/> -</rdf:Bag> -</bqbiol:isEncodedBy> +<rdf:Description rdf:about="#"> </rdf:Description> </rdf:RDF> </annotation> -</species><species metaid="s_id_csa1905" id="s_id_csa1905" name="NMDA_space_receptor" compartment="s_id_ca188" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Name: NMDA selective glutamate receptor complex -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 3 -Charge: 0 -An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. 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-<title/> -</head> -<body>Symbol: CDK5 -Name: cyclin dependent kinase 5 -Synonyms: PSSALRE -HGNC_ID: 1774 -EntrezGene_ID: 1020 -RefSeq_ID: NM_001164410 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11774</celldesigner:proteinReference> -</celldesigner:speciesIdentity> -<celldesigner:listOfCatalyzedReactions> -<celldesigner:catalyzed reaction="re5857"/> -</celldesigner:listOfCatalyzedReactions> -</celldesigner:extension> -<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" 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compartment="s_id_ca173" initialAmount="0" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: PPP1R1B -Name: protein phosphatase 1 regulatory inhibitor subunit 1B -Synonyms: DARPP-32, FLJ20940 -HGNC_ID: 9287 -EntrezGene_ID: 84152 -RefSeq_ID: NM_032192 -SemanticZoomLevelVisibility: 5 -TransparencyZoomLevelVisibility: 0 -Charge: 0 -</body> -</html> -</notes> -<annotation> -<celldesigner:extension> -<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11779</celldesigner:proteinReference> -<celldesigner:state> -<celldesigner:listOfModifications> -<celldesigner:modification residue="rs2" state="phosphorylated"/> -<celldesigner:modification residue="rs3" state="phosphorylated"/> -</celldesigner:listOfModifications> -</celldesigner:state> -</celldesigner:speciesIdentity> 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The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. 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xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> -<rdf:Description rdf:about="#"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:1509"/></rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CASP8"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q14790"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:841"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001228"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000064012"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -</rdf:Description> -</rdf:RDF> -</body> -</html> -</notes> +</speciesReference> +</listOfReactants> +<listOfProducts> +<speciesReference species="s_id_sa11706" > <annotation> <celldesigner:extension> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11890</celldesigner:proteinReference> -</celldesigner:speciesIdentity> +<celldesigner:alias>sa11706</celldesigner:alias> </celldesigner:extension> </annotation> -</species><species metaid="s_id_sa11889" id="s_id_sa11889" name="CASP8_space_(p18)" compartment="s_id_ca188" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: CASP8 -Name: caspase 8 -Synonyms: Casp-8, FLICE, MACH, MCH5 -HGNC_ID: 1509 -EntrezGene_ID: 841 -RefSeq_ID: NM_001228 -SemanticZoomLevelVisibility: 3 -TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> -<rdf:Description rdf:about="#"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:1509"/></rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:CASP8"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:Q14790"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:841"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_001228"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000064012"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -</rdf:Description> -</rdf:RDF> -</body> -</html> -</notes> +</speciesReference> +</listOfProducts> +<listOfModifiers> +<modifierSpeciesReference metaid="s_id_sa11713" species="s_id_sa11713"> <annotation> <celldesigner:extension> -<celldesigner:speciesIdentity> -<celldesigner:class>PROTEIN</celldesigner:class> -<celldesigner:proteinReference>p_s_id_sa11889</celldesigner:proteinReference> -</celldesigner:speciesIdentity> +<celldesigner:alias>sa11713</celldesigner:alias> </celldesigner:extension> </annotation> -</species><species metaid="s_id_sa11924" id="s_id_sa11924" name="ROCK2" compartment="s_id_ca188" charge="0"> -<notes> -<html xmlns="http://www.w3.org/1999/xhtml"> -<head> -<title/> -</head> -<body>Symbol: ROCK2 -Name: Rho associated coiled-coil containing protein kinase 2 -HGNC_ID: 10252 -EntrezGene_ID: 9475 -RefSeq_ID: NM_004850, NM_001321643 -SemanticZoomLevelVisibility: 3 -TransparencyZoomLevelVisibility: 0 -<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> -<rdf:Description rdf:about="#"> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ensembl:ENSG00000134318"/></rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:ncbigene:9475"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:refseq:NM_004850"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc:10252"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:hgnc.symbol:ROCK2"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li rdf:resource="urn:miriam:uniprot:O75116"/> -</rdf:Bag> -</bqbiol:isDescribedBy> -<bqbiol:isDescribedBy> -<rdf:Bag> -<rdf:li 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<celldesigner:linkAnchor position="S"/> </celldesigner:linkTarget> -<celldesigner:line width="1.0" color="ff000000"/> +<celldesigner:line width="1.0" color="FF000000" type="Straight" /> </celldesigner:modification> </celldesigner:listOfModification> +<celldesigner:line width="1.0" color="FF000000" type="Straight" /> </celldesigner:extension> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> -<rdf:Description rdf:about="#re5879"> +<rdf:Description rdf:about="#"> <bqbiol:isDescribedBy> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:pubmed:26872373"/> @@ -21073,7 +15086,7 @@ TransparencyZoomLevelVisibility: 0 </rdf:RDF> </annotation> <listOfReactants> -<speciesReference metaid="CDMT00251" species="s_id_sa11781"> +<speciesReference species="s_id_sa11781" > <annotation> <celldesigner:extension> <celldesigner:alias>sa11781</celldesigner:alias> @@ -21082,7 +15095,7 @@ TransparencyZoomLevelVisibility: 0 </speciesReference> </listOfReactants> <listOfProducts> -<speciesReference metaid="CDMT00252" species="s_id_sa11843"> +<speciesReference species="s_id_sa11843" > <annotation> <celldesigner:extension> <celldesigner:alias>sa11780</celldesigner:alias> @@ -21091,7 +15104,7 @@ TransparencyZoomLevelVisibility: 0 </speciesReference> </listOfProducts> <listOfModifiers> -<modifierSpeciesReference metaid="CDMT00253" species="s_id_csa1914"> +<modifierSpeciesReference metaid="s_id_csa1914" species="s_id_csa1914"> <annotation> <celldesigner:extension> <celldesigner:alias>csa1914</celldesigner:alias> @@ -21100,1663 +15113,1732 @@ TransparencyZoomLevelVisibility: 0 </modifierSpeciesReference> </listOfModifiers> </reaction> -<reaction metaid="re5866" id="re5866" reversible="false"> +<reaction metaid="re5872" id="re5872" name="" 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target="_blank">here</a> .</notes></model></sbml> \ No newline at end of file