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# Retrieval of gene-disease and variation-disease mapping

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The purpose of the tools in this directory is to obtain list of genes and
variants in those genes which are associated with given diseases. Currently, 
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the pipeline to retrieve the genes and variants works as follows:
 
 1. Use ClinVar, DisGeNET, OpenTargets to obtain the gene-disease association and 
variants. 
 2. Extend the genes list by looking into additional resources such as OmniPath.
 3. Use Ensembl to assesses allele frequencies of the identified variants to 
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filter out possibly non-rare variants.
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 4. Get detailed variant information and compile it into [variant file](https://minerva.pages.uni.lu/doc/user_manual/v14.0/index/#genetic-variant-format) for MINERVA.
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## 1. Gene-disease associations and variants
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The DisGeNET and OpenTargets tools connect to the resource of interest and return a JSON file 
with the following format (this is the minimum specification, the output of the tools
can contain additional fields):

```json
{
  "name": "resource_bane",
  "genes": {
    "GENE_SYMBOL": {
      "association_score": 0.5,
      "variants": [
        "rsXXX",
        "rsYYY",
        ...
      ],
      ...
    },
    ...
    }
  ...
}
```
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The ClinVar tool then takes all the output JSON files, compares them against
ClinVar and outputs a report showing genes which are shared or unique in the respective
resources. This report is then passed to the following stages of the pipeline.
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#### DisGeNET
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[DisGeNET](http://www.disgenet.org/) is used to retrieve both gene-disease mapping and variants
using its [API](http://www.disgenet.org/api/). The scripts accepts an Orphan ID of the disease
of interest and looks up the UMLS ID (DisGeNET's identifier) 
via the [Ontology Lookup Service](https://www.ebi.ac.uk/ols/index) 
API.

Usage:

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```bash
python disgenet.py -o orphanet_ids [-n max_number_of_genes] [-s association_score_threshold]  
```
- `orphanet_ids` is comma-separated list of Orphanet identifiers.
- The number of results can be restricted either by the number of genes which should be
retrieved and/or by the [association score](https://www.disgenet.org/help#section22). 
One might want to play with these values to obtain a reasonable number of genes 
for given disease.

#### Opentargets

The [OpenTargets](https://www.opentargets.org/) is used to retrieve both gene-disease mapping and variants
via its [API](https://docs.targetvalidation.org/programmatic-access/rest-api)

Usage:

```bash
python disgenet.py -o orphanet_id [-n max_number_of_genes] [-s association_score_threshold] 
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```

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- `orphanet_ids` is comma-separated list of Orphanet identifiers.
- The number of results can be restricted either by the number of genes which should be
retrieved and/or by the [association score](https://docs.targetvalidation.org/getting-started/scoring).
The output contains not only the overall association score, but also the constituent scores (genetic association, 
text mining, drugs, ...). However, currently it is possible to filter only by the overall score. Please note that
OpenTarget is a bit more general than DisGeNET and when you set the association score threshold to 0 you will
retrieve much more hits than in case of DisGeNET and you might want to further filter those out (maybe by the 
association scores for individual evidences).
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#### ClinVar
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The [ClinVar](https://www.ncbi.nlm.nih.gov/clinvar/) scripts uses a preprocessed file with disease-variants
information which is stored in `association/data/OrphaHPO_clinvar_variants_summary.tsv`. This file
includes for every variant in ClinVar information about disease to which this variant is pertinent, including
Orphanet identifier. 

The OrphaHPO_clinvar_variants_summary is a file obtained from ClinVar FTP on 12th November, 2019. 
It was created by filtering ClinVar variants to keep only those having Orphanet identifier, 
and reducing its contents to GRCh37 (hg19) variants. 

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The script gets genes and variants for given disease, excludes non-pathogenic variants and carries out pairwise comparison
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of genes and variants for ClinVar and all other input resources which are provided as JSON files (see above). The
output is a report on gene and variation level, including list of all genes and variants pertinent to given
disease. 

Usage:

```bash
merge_with_clinvar.py -v disgenet_out_path,opentargets_out_path -c data/OrphaHPO_clinvar_variants_summary.tsv -oid orphanet_ids > ${genes_variants_out_path}
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```
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- `orphanet_ids` is comma-separated list of Orphanet identifiers.
- The list of input JSON files (the `-v` parameter) can have contain number of files allowing to add other resources,
assuming the format of the file follows the convention described above.

Follow an example of output of the `merge_with_clinvar` script for [Brugada syndrom (Orphnet number 130)](https://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=8022&Disease_Disease_Search_diseaseGroup=130&Disease_Disease_Search_diseaseType=ORPHA&Disease(s)/group%20of%20diseases=Brugada-syndrome&title=Brugada%20syndrome&search=Disease_Search_Simple).
The number of DisGeNET genes was limited to 50 (score threshold 0) and the number of OpenTargets 
genese was limited by setting the association threshold to 0.3. 

```text
-------------Gene-level summary-------------
50 disgenet genes: ['ABCC9', 'AKAP9', 'ANK2', 'ATN1', 'BHLHE40', 'CACNA1C', 'CACNA2D1', 'CACNB2', 'CALM1', 'CALM2', 'CALM3', 'CAV3', 'DLG1', 'DSG2', 'DSP', 'EPHA3', 'FGF11', 'FGF12', 'FGF14', 'GPD1L', 'HARS', 'HCN4', 'HEY2', 'HGS', 'IDS', 'KCNA3', 'KCND2', 'KCND3', 'KCNE3', 'KCNE5', 'KCNH2', 'KCNJ8', 'KCNK1', 'MYH7', 'NOS1AP', 'PKP2', 'RANGRF', 'SCN10A', 'SCN1B', 'SCN2B', 'SCN3B', 'SCN4A', 'SCN4B', 'SCN5A', 'SEMA3A', 'SLMAP', 'SRSF5', 'TBX5', 'TRPM4', 'VCL']
15 opentargets genes: ['CACNA1C', 'CACNB2', 'GJA1', 'GPD1L', 'HCN4', 'KCND3', 'KCNE3', 'KCNH2', 'NCOA7', 'NKX2-5', 'RYR2', 'SCN10A', 'SCN1B', 'SCN3B', 'SCN5A']
31 clinvar genes: ['ABCC9', 'ANK2', 'ANKRD1', 'CACNA1C', 'CACNA1C-AS1', 'CACNA2D1', 'CACNB2', 'COL5A1', 'DMD', 'DSP', 'GPD1L', 'HCN4', 'KCND3', 'KCNE1', 'KCNE3', 'KCNE5', 'KCNH2', 'KCNJ8', 'KCNQ1', 'MYBPC3', 'PKP2', 'SCN10A', 'SCN1B', 'SCN3B', 'SCN5A', 'SLMAP', 'SNTA1', 'TCAP', 'TRPM4', 'TTN', 'TTR']

39 genes in disgenet and not in opentargets: ['ABCC9', 'AKAP9', 'ANK2', 'ATN1', 'BHLHE40', 'CACNA2D1', 'CALM1', 'CALM2', 'CALM3', 'CAV3', 'DLG1', 'DSG2', 'DSP', 'EPHA3', 'FGF11', 'FGF12', 'FGF14', 'HARS', 'HEY2', 'HGS', 'IDS', 'KCNA3', 'KCND2', 'KCNE5', 'KCNJ8', 'KCNK1', 'MYH7', 'NOS1AP', 'PKP2', 'RANGRF', 'SCN2B', 'SCN4A', 'SCN4B', 'SEMA3A', 'SLMAP', 'SRSF5', 'TBX5', 'TRPM4', 'VCL']
4 genes in opentargets and not in disgenet: ['GJA1', 'NCOA7', 'NKX2-5', 'RYR2']
30 genes in disgenet and not in clinvar: ['AKAP9', 'ATN1', 'BHLHE40', 'CALM1', 'CALM2', 'CALM3', 'CAV3', 'DLG1', 'DSG2', 'EPHA3', 'FGF11', 'FGF12', 'FGF14', 'HARS', 'HEY2', 'HGS', 'IDS', 'KCNA3', 'KCND2', 'KCNK1', 'MYH7', 'NOS1AP', 'RANGRF', 'SCN2B', 'SCN4A', 'SCN4B', 'SEMA3A', 'SRSF5', 'TBX5', 'VCL']
11 genes in clinvar and not in disgenet: ['ANKRD1', 'CACNA1C-AS1', 'COL5A1', 'DMD', 'KCNE1', 'KCNQ1', 'MYBPC3', 'SNTA1', 'TCAP', 'TTN', 'TTR']
4 genes in opentargets and not in disgenet: ['GJA1', 'NCOA7', 'NKX2-5', 'RYR2']
39 genes in disgenet and not in opentargets: ['ABCC9', 'AKAP9', 'ANK2', 'ATN1', 'BHLHE40', 'CACNA2D1', 'CALM1', 'CALM2', 'CALM3', 'CAV3', 'DLG1', 'DSG2', 'DSP', 'EPHA3', 'FGF11', 'FGF12', 'FGF14', 'HARS', 'HEY2', 'HGS', 'IDS', 'KCNA3', 'KCND2', 'KCNE5', 'KCNJ8', 'KCNK1', 'MYH7', 'NOS1AP', 'PKP2', 'RANGRF', 'SCN2B', 'SCN4A', 'SCN4B', 'SEMA3A', 'SLMAP', 'SRSF5', 'TBX5', 'TRPM4', 'VCL']
4 genes in opentargets and not in clinvar: ['GJA1', 'NCOA7', 'NKX2-5', 'RYR2']
20 genes in clinvar and not in opentargets: ['ABCC9', 'ANK2', 'ANKRD1', 'CACNA1C-AS1', 'CACNA2D1', 'COL5A1', 'DMD', 'DSP', 'KCNE1', 'KCNE5', 'KCNJ8', 'KCNQ1', 'MYBPC3', 'PKP2', 'SLMAP', 'SNTA1', 'TCAP', 'TRPM4', 'TTN', 'TTR']
11 genes in clinvar and not in disgenet: ['ANKRD1', 'CACNA1C-AS1', 'COL5A1', 'DMD', 'KCNE1', 'KCNQ1', 'MYBPC3', 'SNTA1', 'TCAP', 'TTN', 'TTR']
30 genes in disgenet and not in clinvar: ['AKAP9', 'ATN1', 'BHLHE40', 'CALM1', 'CALM2', 'CALM3', 'CAV3', 'DLG1', 'DSG2', 'EPHA3', 'FGF11', 'FGF12', 'FGF14', 'HARS', 'HEY2', 'HGS', 'IDS', 'KCNA3', 'KCND2', 'KCNK1', 'MYH7', 'NOS1AP', 'RANGRF', 'SCN2B', 'SCN4A', 'SCN4B', 'SEMA3A', 'SRSF5', 'TBX5', 'VCL']
20 genes in clinvar and not in opentargets: ['ABCC9', 'ANK2', 'ANKRD1', 'CACNA1C-AS1', 'CACNA2D1', 'COL5A1', 'DMD', 'DSP', 'KCNE1', 'KCNE5', 'KCNJ8', 'KCNQ1', 'MYBPC3', 'PKP2', 'SLMAP', 'SNTA1', 'TCAP', 'TRPM4', 'TTN', 'TTR']
4 genes in opentargets and not in clinvar: ['GJA1', 'NCOA7', 'NKX2-5', 'RYR2']

-------------Variant-level summary-------------
290 disgenet variants: [('CACNA1C', 'rs121912776'), ('CACNA1C', 'rs765116077'), ('GPD1L', 'rs72552291'), ('KCNH2', 'rs12720441'), ('KCNH2', 'rs199473547'), ('KCNJ8', 'rs72554071'), ('NOS1AP', 'rs10494366'), ('RANGRF', 'rs751751942'), ('SCN10A', 'rs10428132'), ('SCN2B', 'rs587777023'), ('SCN3B', 'rs121918282'), ('SCN3B', 'rs147205617'), ('SCN5A', 'rs1060501114'), ('SCN5A', 'rs1060501127'), ('SCN5A', 'rs1060501130'), ('SCN5A', 'rs1060501135'), ('SCN5A', 'rs1060501136'), ('SCN5A', 'rs1060501142'), ('SCN5A', 'rs1060501145'), ('SCN5A', 'rs1064792926'), ('SCN5A', 'rs1131691708'), ('SCN5A', 'rs11708996'), ('SCN5A', 'rs12720452'), ('SCN5A', 'rs137854600'), ('SCN5A', 'rs137854601'), ('SCN5A', 'rs137854602'), ('SCN5A', 'rs137854603'), ('SCN5A', 'rs137854604'), ('SCN5A', 'rs137854606'), ('SCN5A', 'rs137854607'), ('SCN5A', 'rs137854609'), ('SCN5A', 'rs137854611'), ('SCN5A', 'rs137854612'), ('SCN5A', 'rs137854614'), ('SCN5A', 'rs137854615'), ('SCN5A', 'rs137854616'), ('SCN5A', 'rs137854617'), ('SCN5A', 'rs137854618'), ('SCN5A', 'rs1805124'), ('SCN5A', 'rs185492581'), ('SCN5A', 'rs185638763'), ('SCN5A', 'rs193922726'), ('SCN5A', 'rs199473045'), ('SCN5A', 'rs199473050'), ('SCN5A', 'rs199473051'), ('SCN5A', 'rs199473052'), ('SCN5A', 'rs199473053'), ('SCN5A', 'rs199473054'), ('SCN5A', 'rs199473055'), ('SCN5A', 'rs199473056'), ('SCN5A', 'rs199473058'), ('SCN5A', 'rs199473061'), ('SCN5A', 'rs199473062'), ('SCN5A', 'rs199473063'), ('SCN5A', 'rs199473065'), ('SCN5A', 'rs199473066'), ('SCN5A', 'rs199473067'), ('SCN5A', 'rs199473070'), ('SCN5A', 'rs199473072'), ('SCN5A', 'rs199473074'), ('SCN5A', 'rs199473076'), ('SCN5A', 'rs199473079'), ('SCN5A', 'rs199473081'), ('SCN5A', 'rs199473082'), ('SCN5A', 'rs199473083'), ('SCN5A', 'rs199473086'), ('SCN5A', 'rs199473088'), ('SCN5A', 'rs199473090'), ('SCN5A', 'rs199473091'), ('SCN5A', 'rs199473092'), ('SCN5A', 'rs199473093'), ('SCN5A', 'rs199473095'), ('SCN5A', 'rs199473096'), ('SCN5A', 'rs199473097'), ('SCN5A', 'rs199473098'), ('SCN5A', 'rs199473101'), ('SCN5A', 'rs199473102'), ('SCN5A', 'rs199473103'), ('SCN5A', 'rs199473104'), ('SCN5A', 'rs199473117'), ('SCN5A', 'rs199473122'), ('SCN5A', 'rs199473124'), ('SCN5A', 'rs199473133'), ('SCN5A', 'rs199473134'), ('SCN5A', 'rs199473137'), ('SCN5A', 'rs199473139'), ('SCN5A', 'rs199473143'), ('SCN5A', 'rs199473144'), ('SCN5A', 'rs199473147'), ('SCN5A', 'rs199473149'), ('SCN5A', 'rs199473153'), ('SCN5A', 'rs199473154'), ('SCN5A', 'rs199473156'), ('SCN5A', 'rs199473157'), ('SCN5A', 'rs199473158'), ('SCN5A', 'rs199473159'), ('SCN5A', 'rs199473160'), ('SCN5A', 'rs199473161'), ('SCN5A', 'rs199473164'), ('SCN5A', 'rs199473167'), ('SCN5A', 'rs199473168'), ('SCN5A', 'rs199473169'), ('SCN5A', 'rs199473170'), ('SCN5A', 'rs199473171'), ('SCN5A', 'rs199473172'), ('SCN5A', 'rs199473173'), ('SCN5A', 'rs199473174'), ('SCN5A', 'rs199473175'), ('SCN5A', 'rs199473176'), ('SCN5A', 'rs199473178'), ('SCN5A', 'rs199473179'), ('SCN5A', 'rs199473180'), ('SCN5A', 'rs199473181'), ('SCN5A', 'rs199473188'), ('SCN5A', 'rs199473194'), ('SCN5A', 'rs199473199'), ('SCN5A', 'rs199473204'), ('SCN5A', 'rs199473205'), ('SCN5A', 'rs199473206'), ('SCN5A', 'rs199473207'), ('SCN5A', 'rs199473208'), ('SCN5A', 'rs199473210'), ('SCN5A', 'rs199473211'), ('SCN5A', 'rs199473213'), ('SCN5A', 'rs199473214'), ('SCN5A', 'rs199473217'), ('SCN5A', 'rs199473219'), ('SCN5A', 'rs199473220'), ('SCN5A', 'rs199473221'), ('SCN5A', 'rs199473225'), ('SCN5A', 'rs199473228'), ('SCN5A', 'rs199473229'), ('SCN5A', 'rs199473230'), ('SCN5A', 'rs199473231'), ('SCN5A', 'rs199473232'), ('SCN5A', 'rs199473233'), ('SCN5A', 'rs199473234'), ('SCN5A', 'rs199473235'), ('SCN5A', 'rs199473236'), ('SCN5A', 'rs199473237'), ('SCN5A', 'rs199473239'), ('SCN5A', 'rs199473240'), ('SCN5A', 'rs199473241'), ('SCN5A', 'rs199473242'), ('SCN5A', 'rs199473244'), ('SCN5A', 'rs199473245'), ('SCN5A', 'rs199473246'), ('SCN5A', 'rs199473247'), ('SCN5A', 'rs199473248'), ('SCN5A', 'rs199473249'), ('SCN5A', 'rs199473250'), ('SCN5A', 'rs199473251'), ('SCN5A', 'rs199473252'), ('SCN5A', 'rs199473254'), ('SCN5A', 'rs199473261'), ('SCN5A', 'rs199473266'), ('SCN5A', 'rs199473267'), ('SCN5A', 'rs199473269'), ('SCN5A', 'rs199473270'), ('SCN5A', 'rs199473271'), ('SCN5A', 'rs199473273'), ('SCN5A', 'rs199473274'), ('SCN5A', 'rs199473275'), ('SCN5A', 'rs199473280'), ('SCN5A', 'rs199473281'), ('SCN5A', 'rs199473282'), ('SCN5A', 'rs199473287'), ('SCN5A', 'rs199473289'), ('SCN5A', 'rs199473292'), ('SCN5A', 'rs199473293'), ('SCN5A', 'rs199473294'), ('SCN5A', 'rs199473295'), ('SCN5A', 'rs199473297'), ('SCN5A', 'rs199473298'), ('SCN5A', 'rs199473299'), ('SCN5A', 'rs199473302'), ('SCN5A', 'rs199473304'), ('SCN5A', 'rs199473305'), ('SCN5A', 'rs199473309'), ('SCN5A', 'rs199473311'), ('SCN5A', 'rs199473315'), ('SCN5A', 'rs199473316'), ('SCN5A', 'rs199473318'), ('SCN5A', 'rs199473320'), ('SCN5A', 'rs199473322'), ('SCN5A', 'rs199473323'), ('SCN5A', 'rs199473329'), ('SCN5A', 'rs199473554'), ('SCN5A', 'rs199473556'), ('SCN5A', 'rs199473557'), ('SCN5A', 'rs199473558'), ('SCN5A', 'rs199473559'), ('SCN5A', 'rs199473560'), ('SCN5A', 'rs199473561'), ('SCN5A', 'rs199473562'), ('SCN5A', 'rs199473564'), ('SCN5A', 'rs199473565'), ('SCN5A', 'rs199473566'), ('SCN5A', 'rs199473567'), ('SCN5A', 'rs199473568'), ('SCN5A', 'rs199473570'), ('SCN5A', 'rs199473573'), ('SCN5A', 'rs199473574'), ('SCN5A', 'rs199473577'), ('SCN5A', 'rs199473582'), ('SCN5A', 'rs199473584'), ('SCN5A', 'rs199473586'), ('SCN5A', 'rs199473587'), ('SCN5A', 'rs199473588'), ('SCN5A', 'rs199473589'), ('SCN5A', 'rs199473592'), ('SCN5A', 'rs199473593'), ('SCN5A', 'rs199473597'), ('SCN5A', 'rs199473599'), ('SCN5A', 'rs199473601'), ('SCN5A', 'rs199473605'), ('SCN5A', 'rs199473608'), ('SCN5A', 'rs199473609'), ('SCN5A', 'rs199473610'), ('SCN5A', 'rs199473611'), ('SCN5A', 'rs199473612'), ('SCN5A', 'rs199473613'), ('SCN5A', 'rs199473614'), ('SCN5A', 'rs199473617'), ('SCN5A', 'rs199473620'), ('SCN5A', 'rs199473621'), ('SCN5A', 'rs199473623'), ('SCN5A', 'rs199473624'), ('SCN5A', 'rs199473625'), ('SCN5A', 'rs199473626'), ('SCN5A', 'rs199473628'), ('SCN5A', 'rs199473629'), ('SCN5A', 'rs199473634'), ('SCN5A', 'rs199473636'), ('SCN5A', 'rs199473637'), ('SCN5A', 'rs199473639'), ('SCN5A', 'rs28937316'), ('SCN5A', 'rs28937318'), ('SCN5A', 'rs35310524'), ('SCN5A', 'rs370438420'), ('SCN5A', 'rs3918389'), ('SCN5A', 'rs397514251'), ('SCN5A', 'rs41261344'), ('SCN5A', 'rs41311087'), ('SCN5A', 'rs41311117'), ('SCN5A', 'rs41311127'), ('SCN5A', 'rs41315493'), ('SCN5A', 'rs45471994'), ('SCN5A', 'rs45514691'), ('SCN5A', 'rs45546039'), ('SCN5A', 'rs45609733'), ('SCN5A', 'rs45620037'), ('SCN5A', 'rs45627438'), ('SCN5A', 'rs483353016'), ('SCN5A', 'rs72549410'), ('SCN5A', 'rs727503411'), ('SCN5A', 'rs727504801'), ('SCN5A', 'rs727505158'), ('SCN5A', 'rs747643709'), ('SCN5A', 'rs748312802'), ('SCN5A', 'rs749697698'), ('SCN5A', 'rs756159737'), ('SCN5A', 'rs759235726'), ('SCN5A', 'rs759924541'), ('SCN5A', 'rs769349991'), ('SCN5A', 'rs775234338'), ('SCN5A', 'rs775538425'), ('SCN5A', 'rs777689378'), ('SCN5A', 'rs786204839'), ('SCN5A', 'rs79299226'), ('SCN5A', 'rs794728843'), ('SCN5A', 'rs794728846'), ('SCN5A', 'rs794728849'), ('SCN5A', 'rs794728865'), ('SCN5A', 'rs794728879'), ('SCN5A', 'rs794728906'), ('SCN5A', 'rs794728911'), ('SCN5A', 'rs794728912'), ('SCN5A', 'rs794728914'), ('SCN5A', 'rs794728924'), ('SCN5A', 'rs794728931'), ('SCN5A', 'rs863224532'), ('SCN5A', 'rs863224533'), ('SCN5A', 'rs863225273'), ('SCN5A', 'rs864622270'), ('SCN5A', 'rs869025520'), ('SCN5A', 'rs869025522'), ('SCN5A', 'rs878855287'), ('SCN5A', 'rs886037904'), ('VCL', 'rs774870551')]
0 opentargets variants: []
1217 clinvar variants: [('ANK2', 'rs148405740'), ('ANK2', 'rs730880049'), ('ANKRD1', 'rs869025363'), ('CACNA1C', 'rs1057518456'), ('CACNA1C', 'rs111442547'), ('CACNA1C', 'rs111606207'), ('CACNA1C', 'rs112170830'), ('CACNA1C', 'rs121912775'), ('CACNA1C', 'rs121912776'), ('CACNA1C', 'rs12828687'), ('CACNA1C', 'rs142476147'), ('CACNA1C', 'rs186015395'), ('CACNA1C', 'rs186708407'), ('CACNA1C', 'rs186741807'), ('CACNA1C', 'rs199473391'), ('CACNA1C', 'rs199473392'), ('CACNA1C', 'rs199473660'), ('CACNA1C', 'rs199538058'), ('CACNA1C', 'rs199694744'), ('CACNA1C', 'rs200231105'), ('CACNA1C', 'rs200588235'), ('CACNA1C', 'rs201258230'), ('CACNA1C', 'rs201492706'), ('CACNA1C', 'rs201756421'), ('CACNA1C', 'rs367895193'), ('CACNA1C', 'rs369267978'), ('CACNA1C', 'rs369438564'), ('CACNA1C', 'rs369673473'), ('CACNA1C', 'rs370145265'), ('CACNA1C', 'rs370630496'), ('CACNA1C', 'rs374857905'), ('CACNA1C', 'rs375818733'), ('CACNA1C', 'rs376987352'), ('CACNA1C', 'rs377165829'), ('CACNA1C', 'rs533634115'), ('CACNA1C', 'rs545511851'), ('CACNA1C', 'rs547615657'), ('CACNA1C', 'rs555721726'), ('CACNA1C', 'rs561365937'), ('CACNA1C', 'rs563090568'), ('CACNA1C', 'rs56394008'), ('CACNA1C', 'rs567401056'), ('CACNA1C', 'rs748926089'), ('CACNA1C', 'rs749753216'), ('CACNA1C', 'rs751166285'), ('CACNA1C', 'rs752000790'), ('CACNA1C', 'rs752736296'), ('CACNA1C', 'rs753892795'), ('CACNA1C', 'rs755167125'), ('CACNA1C', 'rs755579963'), ('CACNA1C', 'rs756364065'), ('CACNA1C', 'rs757966245'), ('CACNA1C', 'rs758461435'), ('CACNA1C', 'rs760888275'), ('CACNA1C', 'rs762376206'), ('CACNA1C', 'rs763622598'), ('CACNA1C', 'rs764323907'), ('CACNA1C', 'rs767190987'), ('CACNA1C', 'rs768270021'), ('CACNA1C', 'rs768830617'), ('CACNA1C', 'rs773930851'), ('CACNA1C', 'rs774165526'), ('CACNA1C', 'rs774490908'), ('CACNA1C', 'rs775331521'), ('CACNA1C', 'rs776522592'), ('CACNA1C', 'rs778220127'), ('CACNA1C', 'rs779009338'), ('CACNA1C', 'rs779194497'), ('CACNA1C', 'rs781395450'), ('CACNA1C', 'rs886038918'), ('CACNA1C', 'rs886039214'), ('CACNA1C', 'rs886049148'), ('CACNA1C', 'rs886049149'), ('CACNA1C', 'rs886049150'), ('CACNA1C', 'rs886049202'), ('CACNA1C', 'rs886049203'), ('CACNA1C', 'rs886049204'), ('CACNA1C', 'rs886049205'), ('CACNA1C', 'rs886049206'), ('CACNA1C', 'rs886049207'), ('CACNA1C', 'rs886049208'), ('CACNA1C', 'rs886049209'), ('CACNA1C', 'rs886049210'), ('CACNA1C', 'rs886049211'), ('CACNA1C', 'rs886049212'), ('CACNA1C', 'rs886049213'), ('CACNA1C', 'rs886049214'), ('CACNA1C', 'rs886049216'), ('CACNA1C', 'rs886049217'), ('CACNA1C', 'rs886049218'), ('CACNA1C', 'rs886049219'), ('CACNA1C', 'rs886049221'), ('CACNA1C', 'rs886049222'), ('CACNA1C', 'rs886049223'), ('CACNA1C', 'rs886049224'), ('CACNA1C', 'rs886049225'), ('CACNA1C', 'rs886049226'), ('CACNA1C', 'rs886049227'), ('CACNA1C', 'rs886049228'), ('CACNA1C', 'rs886049229'), ('CACNA1C', 'rs886049230'), ('CACNA1C', 'rs886049231'), ('CACNA1C', 'rs886049232'), ('CACNA1C', 'rs886049233'), ('CACNA1C', 'rs886049234'), ('CACNA1C', 'rs886049235'), ('CACNA1C', 'rs886049236'), ('CACNA1C', 'rs886049237'), ('CACNA1C', 'rs886049238'), ('CACNA1C', 'rs886049239'), ('CACNA1C', 'rs886049240'), ('CACNA1C', 'rs886049241'), ('CACNA1C', 'rs886049243'), ('CACNA1C', 'rs886049244'), ('CACNA1C', 'rs886049245'), ('CACNA1C', 'rs886049246'), ('CACNA1C', 'rs886049247'), ('CACNA1C', 'rs886049248'), ('CACNA1C', 'rs886049249'), ('CACNA1C', 'rs886049250'), ('CACNA1C', 'rs886049251'), ('CACNA1C-AS1', 'rs200231105'), ('CACNA2D1', 'rs1060503151'), ('CACNA2D1', 'rs1163800062'), ('CACNA2D1', 'rs1218449046'), ('CACNA2D1', 'rs139608070'), ('CACNA2D1', 'rs141238313'), ('CACNA2D1', 'rs1477267428'), ('CACNA2D1', 'rs1554327285'), ('CACNA2D1', 'rs1554333986'), ('CACNA2D1', 'rs1554345090'), ('CACNA2D1', 'rs1554349582'), ('CACNA2D1', 'rs1554398187'), ('CACNA2D1', 'rs1554560384'), ('CACNA2D1', 'rs192741898'), ('CACNA2D1', 'rs201682618'), ('CACNA2D1', 'rs202108848'), ('CACNA2D1', 'rs368512946'), ('CACNA2D1', 'rs745501384'), ('CACNA2D1', 'rs756765026'), ('CACNA2D1', 'rs757313687'), ('CACNA2D1', 'rs771243374'), ('CACNA2D1', 'rs773095610'), ('CACNA2D1', 'rs780901801'), ('CACNA2D1', 'rs869025369'), ('CACNB2', 'rs1064795457'), ('CACNB2', 'rs111250176'), ('CACNB2', 'rs137886839'), ('CACNB2', 'rs138423466'), ('CACNB2', 'rs143326262'), ('CACNB2', 'rs144182966'), ('CACNB2', 'rs144509796'), ('CACNB2', 'rs149253719'), ('CACNB2', 'rs149793143'), ('CACNB2', 'rs150280879'), ('CACNB2', 'rs150528041'), ('CACNB2', 'rs151199943'), ('CACNB2', 'rs1554843746'), ('CACNB2', 'rs182163363'), ('CACNB2', 'rs182634399'), ('CACNB2', 'rs187815725'), ('CACNB2', 'rs191106518'), ('CACNB2', 'rs192508010'), ('CACNB2', 'rs200654601'), ('CACNB2', 'rs202152674'), ('CACNB2', 'rs34551674'), ('CACNB2', 'rs367928065'), ('CACNB2', 'rs368719191'), ('CACNB2', 'rs373932682'), ('CACNB2', 'rs376222853'), ('CACNB2', 'rs528559406'), ('CACNB2', 'rs536419495'), ('CACNB2', 'rs543872505'), ('CACNB2', 'rs546669133'), ('CACNB2', 'rs547804393'), ('CACNB2', 'rs551293049'), ('CACNB2', 'rs562896922'), ('CACNB2', 'rs564275776'), ('CACNB2', 'rs564407056'), ('CACNB2', 'rs568890834'), ('CACNB2', 'rs568986179'), ('CACNB2', 'rs61733968'), ('CACNB2', 'rs745337273'), ('CACNB2', 'rs750396182'), ('CACNB2', 'rs752637408'), ('CACNB2', 'rs753335762'), ('CACNB2', 'rs758274878'), ('CACNB2', 'rs759258778'), ('CACNB2', 'rs764843384'), ('CACNB2', 'rs76956014'), ('CACNB2', 'rs773767571'), ('CACNB2', 'rs775466397'), ('CACNB2', 'rs775896337'), ('CACNB2', 'rs778295363'), ('CACNB2', 'rs780734976'), ('CACNB2', 'rs781283574'), ('CACNB2', 'rs78378025'), ('CACNB2', 'rs875989812'), ('CACNB2', 'rs886046883'), ('CACNB2', 'rs886046884'), ('CACNB2', 'rs886046885'), ('CACNB2', 'rs886046886'), ('CACNB2', 'rs886046887'), ('CACNB2', 'rs886046891'), ('CACNB2', 'rs886046892'), ('CACNB2', 'rs886046893'), ('CACNB2', 'rs886046894'), ('CACNB2', 'rs886046896'), ('CACNB2', 'rs886046897'), ('CACNB2', 'rs886046898'), ('CACNB2', 'rs886046899'), ('CACNB2', 'rs886046901'), ('CACNB2', 'rs886046902'), ('CACNB2', 'rs886046906'), ('CACNB2', 'rs886046907'), ('CACNB2', 'rs886046908'), ('COL5A1', 'rs1564417691'), ('GPD1L', 'rs112122950'), ('GPD1L', 'rs112185839'), ('GPD1L', 'rs113764055'), ('GPD1L', 'rs114349261'), ('GPD1L', 'rs115291555'), ('GPD1L', 'rs116281194'), ('GPD1L', 'rs1216770303'), ('GPD1L', 'rs1376727184'), ('GPD1L', 'rs139494055'), ('GPD1L', 'rs140250795'), ('GPD1L', 'rs143486835'), ('GPD1L', 'rs144925784'), ('GPD1L', 'rs148361833'), ('GPD1L', 'rs148464224'), ('GPD1L', 'rs149641866'), ('GPD1L', 'rs1553659648'), ('GPD1L', 'rs1553660781'), ('GPD1L', 'rs1559565644'), ('GPD1L', 'rs1559579249'), ('GPD1L', 'rs182826539'), ('GPD1L', 'rs186019566'), ('GPD1L', 'rs201799095'), ('GPD1L', 'rs373602669'), ('GPD1L', 'rs531920801'), ('GPD1L', 'rs537616228'), ('GPD1L', 'rs538672341'), ('GPD1L', 'rs546574502'), ('GPD1L', 'rs558257162'), ('GPD1L', 'rs566007803'), ('GPD1L', 'rs72546642'), ('GPD1L', 'rs72546651'), ('GPD1L', 'rs72552291'), ('GPD1L', 'rs72552292'), ('GPD1L', 'rs72552294'), ('GPD1L', 'rs72558074'), ('GPD1L', 'rs755306391'), ('GPD1L', 'rs757146653'), ('GPD1L', 'rs757614405'), ('GPD1L', 'rs757638347'), ('GPD1L', 'rs759080305'), ('GPD1L', 'rs772985306'), ('GPD1L', 'rs777110449'), ('GPD1L', 'rs786204216'), ('GPD1L', 'rs786205268'), ('GPD1L', 'rs878855004'), ('GPD1L', 'rs886058331'), ('GPD1L', 'rs886058332'), ('GPD1L', 'rs886058333'), ('GPD1L', 'rs886058334'), ('GPD1L', 'rs886058335'), ('GPD1L', 'rs886058336'), ('GPD1L', 'rs886058337'), ('GPD1L', 'rs886058338'), ('HCN4', 'rs560874115'), ('HCN4', 'rs764493888'), ('KCND3', 'rs869025444'), ('KCNE1', 'rs74315445'), ('KCNE3', 'rs113583236'), ('KCNE3', 'rs121908441'), ('KCNE3', 'rs150406522'), ('KCNE3', 'rs182905404'), ('KCNE3', 'rs187700411'), ('KCNE3', 'rs191005723'), ('KCNE3', 'rs201843136'), ('KCNE3', 'rs41258394'), ('KCNE3', 'rs41315539'), ('KCNE3', 'rs41315541'), ('KCNE3', 'rs528760350'), ('KCNE3', 'rs529326016'), ('KCNE3', 'rs535500151'), ('KCNE3', 'rs540669024'), ('KCNE3', 'rs546242304'), ('KCNE3', 'rs549819195'), ('KCNE3', 'rs555082306'), ('KCNE3', 'rs566273812'), ('KCNE3', 'rs569357069'), ('KCNE3', 'rs570472222'), ('KCNE3', 'rs60016728'), ('KCNE3', 'rs72552105'), ('KCNE3', 'rs745623708'), ('KCNE3', 'rs753304260'), ('KCNE3', 'rs758082514'), ('KCNE3', 'rs764717543'), ('KCNE3', 'rs867623173'), ('KCNE3', 'rs886048645'), ('KCNE3', 'rs886048646'), ('KCNE3', 'rs886048647'), ('KCNE3', 'rs886048648'), ('KCNE3', 'rs886048650'), ('KCNE3', 'rs886048651'), ('KCNE3', 'rs886048652'), ('KCNE3', 'rs886048653'), ('KCNE3', 'rs886048654'), ('KCNE5', 'rs1420621771'), ('KCNE5', 'rs375008004'), ('KCNE5', 'rs764993726'), ('KCNH2', 'rs12720441'), ('KCNJ8', 'rs117808169'), ('KCNJ8', 'rs149127157'), ('KCNJ8', 'rs1555172510'), ('KCNJ8', 'rs1565662161'), ('KCNJ8', 'rs730880120'), ('KCNQ1', 'rs775608046'), ('MYBPC3', 'rs397515985'), ('PKP2', 'rs146882581'), ('PKP2', 'rs149930872'), ('SCN10A', 'rs1060501715'), ('SCN10A', 'rs1060501716'), ('SCN10A', 'rs1060501717'), ('SCN10A', 'rs1167279918'), ('SCN10A', 'rs1173154320'), ('SCN10A', 'rs1199205585'), ('SCN10A', 'rs1226072923'), ('SCN10A', 'rs1265687114'), ('SCN10A', 'rs1334180362'), ('SCN10A', 'rs1334461772'), ('SCN10A', 'rs1372622252'), ('SCN10A', 'rs1373914068'), ('SCN10A', 'rs138404783'), ('SCN10A', 'rs138832868'), ('SCN10A', 'rs139638446'), ('SCN10A', 'rs1397301108'), ('SCN10A', 'rs139861061'), ('SCN10A', 'rs140288103'), ('SCN10A', 'rs140825889'), ('SCN10A', 'rs141368548'), ('SCN10A', 'rs141810266'), ('SCN10A', 'rs142203439'), ('SCN10A', 'rs142235256'), ('SCN10A', 'rs142276689'), ('SCN10A', 'rs142884499'), ('SCN10A', 'rs143744796'), ('SCN10A', 'rs1450059546'), ('SCN10A', 'rs145032037'), ('SCN10A', 'rs145694222'), ('SCN10A', 'rs145712124'), ('SCN10A', 'rs146965005'), ('SCN10A', 'rs147844607'), ('SCN10A', 'rs148537653'), ('SCN10A', 'rs148663098'), ('SCN10A', 'rs149155352'), ('SCN10A', 'rs149504103'), ('SCN10A', 'rs150923753'), ('SCN10A', 'rs151303346'), ('SCN10A', 'rs1553612991'), ('SCN10A', 'rs1553613078'), ('SCN10A', 'rs1553614805'), ('SCN10A', 'rs1553616744'), ('SCN10A', 'rs1553619005'), ('SCN10A', 'rs1553623225'), ('SCN10A', 'rs1553625946'), ('SCN10A', 'rs1553626242'), ('SCN10A', 'rs1553626259'), ('SCN10A', 'rs1559407312'), ('SCN10A', 'rs1559409413'), ('SCN10A', 'rs1559414131'), ('SCN10A', 'rs1559414230'), ('SCN10A', 'rs1559415879'), ('SCN10A', 'rs1559419984'), ('SCN10A', 'rs1559424975'), ('SCN10A', 'rs192493052'), ('SCN10A', 'rs199503439'), ('SCN10A', 'rs199535863'), ('SCN10A', 'rs199715855'), ('SCN10A', 'rs199931920'), ('SCN10A', 'rs200645452'), ('SCN10A', 'rs200713724'), ('SCN10A', 'rs200714519'), ('SCN10A', 'rs201106879'), ('SCN10A', 'rs201342036'), ('SCN10A', 'rs201706560'), ('SCN10A', 'rs201955990'), ('SCN10A', 'rs202040659'), ('SCN10A', 'rs202174472'), ('SCN10A', 'rs202192818'), ('SCN10A', 'rs370880796'), ('SCN10A', 'rs371337228'), ('SCN10A', 'rs371803816'), ('SCN10A', 'rs371834340'), ('SCN10A', 'rs371909817'), ('SCN10A', 'rs372368062'), ('SCN10A', 'rs372907454'), ('SCN10A', 'rs373289770'), ('SCN10A', 'rs374341474'), ('SCN10A', 'rs374447261'), ('SCN10A', 'rs375926577'), ('SCN10A', 'rs375940680'), ('SCN10A', 'rs377492327'), ('SCN10A', 'rs539215014'), ('SCN10A', 'rs542554745'), ('SCN10A', 'rs553784643'), ('SCN10A', 'rs569261408'), ('SCN10A', 'rs746690639'), ('SCN10A', 'rs747044382'), ('SCN10A', 'rs747174454'), ('SCN10A', 'rs747296872'), ('SCN10A', 'rs747321219'), ('SCN10A', 'rs747486328'), ('SCN10A', 'rs747839312'), ('SCN10A', 'rs747848559'), ('SCN10A', 'rs748441157'), ('SCN10A', 'rs748854017'), ('SCN10A', 'rs750073618'), ('SCN10A', 'rs751252167'), ('SCN10A', 'rs752623537'), ('SCN10A', 'rs754130748'), ('SCN10A', 'rs755100226'), ('SCN10A', 'rs756133876'), ('SCN10A', 'rs756253735'), ('SCN10A', 'rs756547221'), ('SCN10A', 'rs757916036'), ('SCN10A', 'rs758157003'), ('SCN10A', 'rs759136534'), ('SCN10A', 'rs759842238'), ('SCN10A', 'rs762600386'), ('SCN10A', 'rs762798134'), ('SCN10A', 'rs764965507'), ('SCN10A', 'rs766017851'), ('SCN10A', 'rs766143752'), ('SCN10A', 'rs772484960'), ('SCN10A', 'rs774893568'), ('SCN10A', 'rs777258179'), ('SCN10A', 'rs779316495'), ('SCN10A', 'rs781354273'), ('SCN10A', 'rs910678839'), ('SCN1B', 'rs147073518'), ('SCN1B', 'rs72552027'), ('SCN1B', 'rs72558029'), ('SCN1B', 'rs886054339'), ('SCN1B', 'rs886054340'), ('SCN1B', 'rs886054341'), ('SCN3B', 'rs111341342'), ('SCN3B', 'rs114709124'), ('SCN3B', 'rs116885934'), ('SCN3B', 'rs117409744'), ('SCN3B', 'rs121918282'), ('SCN3B', 'rs138774330'), ('SCN3B', 'rs139934383'), ('SCN3B', 'rs144520035'), ('SCN3B', 'rs148244106'), ('SCN3B', 'rs184556043'), ('SCN3B', 'rs187400761'), ('SCN3B', 'rs370826688'), ('SCN3B', 'rs543489443'), ('SCN3B', 'rs544984224'), ('SCN3B', 'rs547303769'), ('SCN3B', 'rs553042856'), ('SCN3B', 'rs555303241'), ('SCN3B', 'rs558085329'), ('SCN3B', 'rs577244366'), ('SCN3B', 'rs72552139'), ('SCN3B', 'rs72552158'), ('SCN3B', 'rs72552164'), ('SCN3B', 'rs72552185'), ('SCN3B', 'rs72552191'), ('SCN3B', 'rs72552193'), ('SCN3B', 'rs72552194'), ('SCN3B', 'rs72552195'), ('SCN3B', 'rs72553906'), ('SCN3B', 'rs72553907'), ('SCN3B', 'rs72553909'), ('SCN3B', 'rs748097809'), ('SCN3B', 'rs751005040'), ('SCN3B', 'rs753258598'), ('SCN3B', 'rs758175811'), ('SCN3B', 'rs75996884'), ('SCN3B', 'rs76257004'), ('SCN3B', 'rs765294617'), ('SCN3B', 'rs77584352'), ('SCN3B', 'rs776449566'), ('SCN3B', 'rs80017720'), ('SCN3B', 'rs867302682'), ('SCN3B', 'rs886047884'), ('SCN3B', 'rs886047885'), ('SCN3B', 'rs886047886'), ('SCN3B', 'rs886047887'), ('SCN3B', 'rs886047888'), ('SCN3B', 'rs886047889'), ('SCN3B', 'rs886047890'), ('SCN3B', 'rs886047891'), ('SCN3B', 'rs886047892'), ('SCN3B', 'rs886047893'), ('SCN3B', 'rs886047894'), ('SCN3B', 'rs886047895'), ('SCN3B', 'rs886047897'), ('SCN3B', 'rs886047898'), ('SCN3B', 'rs886047899'), ('SCN3B', 'rs886047900'), ('SCN3B', 'rs886047901'), ('SCN3B', 'rs886047902'), ('SCN3B', 'rs886047903'), ('SCN3B', 'rs886047904'), ('SCN3B', 'rs886047905'), ('SCN3B', 'rs886047906'), ('SCN3B', 'rs886047907'), ('SCN5A', 'rs1011460663'), ('SCN5A', 'rs1038605800'), ('SCN5A', 'rs1060499900'), ('SCN5A', 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'rs794728910'), ('SCN5A', 'rs794728911'), ('SCN5A', 'rs794728912'), ('SCN5A', 'rs794728914'), ('SCN5A', 'rs794728916'), ('SCN5A', 'rs794728924'), ('SCN5A', 'rs794728925'), ('SCN5A', 'rs794728927'), ('SCN5A', 'rs794728934'), ('SCN5A', 'rs794728935'), ('SCN5A', 'rs794728940'), ('SCN5A', 'rs863224532'), ('SCN5A', 'rs863224533'), ('SCN5A', 'rs863224816'), ('SCN5A', 'rs863225273'), ('SCN5A', 'rs864622270'), ('SCN5A', 'rs864622440'), ('SCN5A', 'rs865884072'), ('SCN5A', 'rs869025517'), ('SCN5A', 'rs869025520'), ('SCN5A', 'rs869025522'), ('SCN5A', 'rs878855287'), ('SCN5A', 'rs878855288'), ('SCN5A', 'rs878855289'), ('SCN5A', 'rs878855292'), ('SCN5A', 'rs878855294'), ('SCN5A', 'rs878855295'), ('SCN5A', 'rs878855296'), ('SCN5A', 'rs878911306'), ('SCN5A', 'rs879035421'), ('SCN5A', 'rs879255356'), ('SCN5A', 'rs886037904'), ('SCN5A', 'rs886058437'), ('SCN5A', 'rs886058438'), ('SCN5A', 'rs886058439'), ('SCN5A', 'rs886058440'), ('SCN5A', 'rs886058441'), ('SCN5A', 'rs886058442'), ('SCN5A', 'rs886058443'), ('SCN5A', 'rs886058444'), ('SCN5A', 'rs886058445'), ('SCN5A', 'rs886058446'), ('SCN5A', 'rs886058447'), ('SCN5A', 'rs886058448'), ('SCN5A', 'rs886058449'), ('SCN5A', 'rs886058450'), ('SCN5A', 'rs886058451'), ('SCN5A', 'rs886058452'), ('SCN5A', 'rs886058453'), ('SCN5A', 'rs886058454'), ('SCN5A', 'rs886058455'), ('SCN5A', 'rs886058456'), ('SCN5A', 'rs886058457'), ('SCN5A', 'rs886058458'), ('SCN5A', 'rs886058459'), ('SCN5A', 'rs886058460'), ('SCN5A', 'rs886058461'), ('SCN5A', 'rs886058462'), ('SCN5A', 'rs886058463'), ('SCN5A', 'rs886058464'), ('SCN5A', 'rs886058465'), ('SCN5A', 'rs886058466'), ('SCN5A', 'rs918933961'), ('SCN5A', 'rs949932623'), ('SCN5A', 'rs9858585'), ('SLMAP', 'rs1016820088'), ('SLMAP', 'rs1060503190'), ('SLMAP', 'rs140490085'), ('SLMAP', 'rs142516364'), ('SLMAP', 'rs142778041'), ('SLMAP', 'rs149548827'), ('SLMAP', 'rs150439110'), ('SLMAP', 'rs746146243'), ('SLMAP', 'rs750893840'), ('SLMAP', 'rs751083292'), ('SLMAP', 'rs754387957'), ('SLMAP', 'rs763740777'), ('SLMAP', 'rs901233405'), ('SNTA1', 'rs137986136'), ('TCAP', 'rs146906267'), ('TRPM4', 'rs172149856'), ('TRPM4', 'rs201907325'), ('TRPM4', 'rs201994425'), ('TRPM4', 'rs747192078'), ('TRPM4', 'rs878855029'), ('TTN', 'rs148067743'), ('TTN', 'rs368327166'), ('TTN', 'rs55980498'), ('TTN', 'rs72646873'), ('TTN', 'rs72648942'), ('TTN', 'rs72650031'), ('TTN', 'rs761362832'), ('TTR', 'rs745834030')]
290 variants in disgenet and not in opentargets: [('CACNA1C', 'rs121912776'), ('CACNA1C', 'rs765116077'), ('GPD1L', 'rs72552291'), ('KCNH2', 'rs12720441'), ('KCNH2', 'rs199473547'), ('KCNJ8', 'rs72554071'), ('NOS1AP', 'rs10494366'), ('RANGRF', 'rs751751942'), ('SCN10A', 'rs10428132'), ('SCN2B', 'rs587777023'), ('SCN3B', 'rs121918282'), ('SCN3B', 'rs147205617'), ('SCN5A', 'rs1060501114'), ('SCN5A', 'rs1060501127'), ('SCN5A', 'rs1060501130'), ('SCN5A', 'rs1060501135'), ('SCN5A', 'rs1060501136'), ('SCN5A', 'rs1060501142'), ('SCN5A', 'rs1060501145'), ('SCN5A', 'rs1064792926'), ('SCN5A', 'rs1131691708'), ('SCN5A', 'rs11708996'), ('SCN5A', 'rs12720452'), ('SCN5A', 'rs137854600'), ('SCN5A', 'rs137854601'), ('SCN5A', 'rs137854602'), ('SCN5A', 'rs137854603'), ('SCN5A', 'rs137854604'), ('SCN5A', 'rs137854606'), ('SCN5A', 'rs137854607'), ('SCN5A', 'rs137854609'), ('SCN5A', 'rs137854611'), ('SCN5A', 'rs137854612'), ('SCN5A', 'rs137854614'), ('SCN5A', 'rs137854615'), ('SCN5A', 'rs137854616'), ('SCN5A', 'rs137854617'), ('SCN5A', 'rs137854618'), ('SCN5A', 'rs1805124'), ('SCN5A', 'rs185492581'), ('SCN5A', 'rs185638763'), ('SCN5A', 'rs193922726'), ('SCN5A', 'rs199473045'), ('SCN5A', 'rs199473050'), ('SCN5A', 'rs199473051'), ('SCN5A', 'rs199473052'), ('SCN5A', 'rs199473053'), ('SCN5A', 'rs199473054'), ('SCN5A', 'rs199473055'), ('SCN5A', 'rs199473056'), ('SCN5A', 'rs199473058'), ('SCN5A', 'rs199473061'), ('SCN5A', 'rs199473062'), ('SCN5A', 'rs199473063'), ('SCN5A', 'rs199473065'), ('SCN5A', 'rs199473066'), ('SCN5A', 'rs199473067'), ('SCN5A', 'rs199473070'), ('SCN5A', 'rs199473072'), ('SCN5A', 'rs199473074'), ('SCN5A', 'rs199473076'), ('SCN5A', 'rs199473079'), ('SCN5A', 'rs199473081'), ('SCN5A', 'rs199473082'), ('SCN5A', 'rs199473083'), ('SCN5A', 'rs199473086'), ('SCN5A', 'rs199473088'), ('SCN5A', 'rs199473090'), ('SCN5A', 'rs199473091'), ('SCN5A', 'rs199473092'), ('SCN5A', 'rs199473093'), ('SCN5A', 'rs199473095'), ('SCN5A', 'rs199473096'), ('SCN5A', 'rs199473097'), ('SCN5A', 'rs199473098'), ('SCN5A', 'rs199473101'), ('SCN5A', 'rs199473102'), ('SCN5A', 'rs199473103'), ('SCN5A', 'rs199473104'), ('SCN5A', 'rs199473117'), ('SCN5A', 'rs199473122'), ('SCN5A', 'rs199473124'), ('SCN5A', 'rs199473133'), ('SCN5A', 'rs199473134'), ('SCN5A', 'rs199473137'), ('SCN5A', 'rs199473139'), ('SCN5A', 'rs199473143'), ('SCN5A', 'rs199473144'), ('SCN5A', 'rs199473147'), ('SCN5A', 'rs199473149'), ('SCN5A', 'rs199473153'), ('SCN5A', 'rs199473154'), ('SCN5A', 'rs199473156'), ('SCN5A', 'rs199473157'), ('SCN5A', 'rs199473158'), ('SCN5A', 'rs199473159'), ('SCN5A', 'rs199473160'), ('SCN5A', 'rs199473161'), ('SCN5A', 'rs199473164'), ('SCN5A', 'rs199473167'), ('SCN5A', 'rs199473168'), ('SCN5A', 'rs199473169'), ('SCN5A', 'rs199473170'), ('SCN5A', 'rs199473171'), ('SCN5A', 'rs199473172'), ('SCN5A', 'rs199473173'), ('SCN5A', 'rs199473174'), ('SCN5A', 'rs199473175'), ('SCN5A', 'rs199473176'), ('SCN5A', 'rs199473178'), ('SCN5A', 'rs199473179'), ('SCN5A', 'rs199473180'), ('SCN5A', 'rs199473181'), ('SCN5A', 'rs199473188'), ('SCN5A', 'rs199473194'), ('SCN5A', 'rs199473199'), ('SCN5A', 'rs199473204'), ('SCN5A', 'rs199473205'), ('SCN5A', 'rs199473206'), ('SCN5A', 'rs199473207'), ('SCN5A', 'rs199473208'), ('SCN5A', 'rs199473210'), ('SCN5A', 'rs199473211'), ('SCN5A', 'rs199473213'), ('SCN5A', 'rs199473214'), ('SCN5A', 'rs199473217'), ('SCN5A', 'rs199473219'), ('SCN5A', 'rs199473220'), ('SCN5A', 'rs199473221'), ('SCN5A', 'rs199473225'), ('SCN5A', 'rs199473228'), ('SCN5A', 'rs199473229'), ('SCN5A', 'rs199473230'), ('SCN5A', 'rs199473231'), ('SCN5A', 'rs199473232'), ('SCN5A', 'rs199473233'), ('SCN5A', 'rs199473234'), ('SCN5A', 'rs199473235'), ('SCN5A', 'rs199473236'), ('SCN5A', 'rs199473237'), ('SCN5A', 'rs199473239'), ('SCN5A', 'rs199473240'), ('SCN5A', 'rs199473241'), ('SCN5A', 'rs199473242'), ('SCN5A', 'rs199473244'), ('SCN5A', 'rs199473245'), ('SCN5A', 'rs199473246'), ('SCN5A', 'rs199473247'), ('SCN5A', 'rs199473248'), ('SCN5A', 'rs199473249'), ('SCN5A', 'rs199473250'), ('SCN5A', 'rs199473251'), ('SCN5A', 'rs199473252'), ('SCN5A', 'rs199473254'), ('SCN5A', 'rs199473261'), ('SCN5A', 'rs199473266'), ('SCN5A', 'rs199473267'), ('SCN5A', 'rs199473269'), ('SCN5A', 'rs199473270'), ('SCN5A', 'rs199473271'), ('SCN5A', 'rs199473273'), ('SCN5A', 'rs199473274'), ('SCN5A', 'rs199473275'), ('SCN5A', 'rs199473280'), ('SCN5A', 'rs199473281'), ('SCN5A', 'rs199473282'), ('SCN5A', 'rs199473287'), ('SCN5A', 'rs199473289'), ('SCN5A', 'rs199473292'), ('SCN5A', 'rs199473293'), ('SCN5A', 'rs199473294'), ('SCN5A', 'rs199473295'), ('SCN5A', 'rs199473297'), ('SCN5A', 'rs199473298'), ('SCN5A', 'rs199473299'), ('SCN5A', 'rs199473302'), ('SCN5A', 'rs199473304'), ('SCN5A', 'rs199473305'), ('SCN5A', 'rs199473309'), ('SCN5A', 'rs199473311'), ('SCN5A', 'rs199473315'), ('SCN5A', 'rs199473316'), ('SCN5A', 'rs199473318'), ('SCN5A', 'rs199473320'), ('SCN5A', 'rs199473322'), ('SCN5A', 'rs199473323'), ('SCN5A', 'rs199473329'), ('SCN5A', 'rs199473554'), ('SCN5A', 'rs199473556'), ('SCN5A', 'rs199473557'), ('SCN5A', 'rs199473558'), ('SCN5A', 'rs199473559'), ('SCN5A', 'rs199473560'), ('SCN5A', 'rs199473561'), ('SCN5A', 'rs199473562'), ('SCN5A', 'rs199473564'), ('SCN5A', 'rs199473565'), ('SCN5A', 'rs199473566'), ('SCN5A', 'rs199473567'), ('SCN5A', 'rs199473568'), ('SCN5A', 'rs199473570'), ('SCN5A', 'rs199473573'), ('SCN5A', 'rs199473574'), ('SCN5A', 'rs199473577'), ('SCN5A', 'rs199473582'), ('SCN5A', 'rs199473584'), ('SCN5A', 'rs199473586'), ('SCN5A', 'rs199473587'), ('SCN5A', 'rs199473588'), ('SCN5A', 'rs199473589'), ('SCN5A', 'rs199473592'), ('SCN5A', 'rs199473593'), ('SCN5A', 'rs199473597'), ('SCN5A', 'rs199473599'), ('SCN5A', 'rs199473601'), ('SCN5A', 'rs199473605'), ('SCN5A', 'rs199473608'), ('SCN5A', 'rs199473609'), ('SCN5A', 'rs199473610'), ('SCN5A', 'rs199473611'), ('SCN5A', 'rs199473612'), ('SCN5A', 'rs199473613'), ('SCN5A', 'rs199473614'), ('SCN5A', 'rs199473617'), ('SCN5A', 'rs199473620'), ('SCN5A', 'rs199473621'), ('SCN5A', 'rs199473623'), ('SCN5A', 'rs199473624'), ('SCN5A', 'rs199473625'), ('SCN5A', 'rs199473626'), ('SCN5A', 'rs199473628'), ('SCN5A', 'rs199473629'), ('SCN5A', 'rs199473634'), ('SCN5A', 'rs199473636'), ('SCN5A', 'rs199473637'), ('SCN5A', 'rs199473639'), ('SCN5A', 'rs28937316'), ('SCN5A', 'rs28937318'), ('SCN5A', 'rs35310524'), ('SCN5A', 'rs370438420'), ('SCN5A', 'rs3918389'), ('SCN5A', 'rs397514251'), ('SCN5A', 'rs41261344'), ('SCN5A', 'rs41311087'), ('SCN5A', 'rs41311117'), ('SCN5A', 'rs41311127'), ('SCN5A', 'rs41315493'), ('SCN5A', 'rs45471994'), ('SCN5A', 'rs45514691'), ('SCN5A', 'rs45546039'), ('SCN5A', 'rs45609733'), ('SCN5A', 'rs45620037'), ('SCN5A', 'rs45627438'), ('SCN5A', 'rs483353016'), ('SCN5A', 'rs72549410'), ('SCN5A', 'rs727503411'), ('SCN5A', 'rs727504801'), ('SCN5A', 'rs727505158'), ('SCN5A', 'rs747643709'), ('SCN5A', 'rs748312802'), ('SCN5A', 'rs749697698'), ('SCN5A', 'rs756159737'), ('SCN5A', 'rs759235726'), ('SCN5A', 'rs759924541'), ('SCN5A', 'rs769349991'), ('SCN5A', 'rs775234338'), ('SCN5A', 'rs775538425'), ('SCN5A', 'rs777689378'), ('SCN5A', 'rs786204839'), ('SCN5A', 'rs79299226'), ('SCN5A', 'rs794728843'), ('SCN5A', 'rs794728846'), ('SCN5A', 'rs794728849'), ('SCN5A', 'rs794728865'), ('SCN5A', 'rs794728879'), ('SCN5A', 'rs794728906'), ('SCN5A', 'rs794728911'), ('SCN5A', 'rs794728912'), ('SCN5A', 'rs794728914'), ('SCN5A', 'rs794728924'), ('SCN5A', 'rs794728931'), ('SCN5A', 'rs863224532'), ('SCN5A', 'rs863224533'), ('SCN5A', 'rs863225273'), ('SCN5A', 'rs864622270'), ('SCN5A', 'rs869025520'), ('SCN5A', 'rs869025522'), ('SCN5A', 'rs878855287'), ('SCN5A', 'rs886037904'), ('VCL', 'rs774870551')]
0 variants in opentargets and not in disgenet: []
30 variants in disgenet and not in clinvar: [('CACNA1C', 'rs765116077'), ('KCNH2', 'rs199473547'), ('KCNJ8', 'rs72554071'), ('NOS1AP', 'rs10494366'), ('RANGRF', 'rs751751942'), ('SCN10A', 'rs10428132'), ('SCN2B', 'rs587777023'), ('SCN3B', 'rs147205617'), ('SCN5A', 'rs11708996'), ('SCN5A', 'rs137854606'), ('SCN5A', 'rs1805124'), ('SCN5A', 'rs199473045'), ('SCN5A', 'rs199473160'), ('SCN5A', 'rs199473204'), ('SCN5A', 'rs199473246'), ('SCN5A', 'rs199473287'), ('SCN5A', 'rs199473293'), ('SCN5A', 'rs199473315'), ('SCN5A', 'rs199473318'), ('SCN5A', 'rs199473625'), ('SCN5A', 'rs35310524'), ('SCN5A', 'rs41261344'), ('SCN5A', 'rs41315493'), ('SCN5A', 'rs747643709'), ('SCN5A', 'rs769349991'), ('SCN5A', 'rs775234338'), ('SCN5A', 'rs775538425'), ('SCN5A', 'rs79299226'), ('SCN5A', 'rs794728931'), ('VCL', 'rs774870551')]
957 variants in clinvar and not in disgenet: [('ANK2', 'rs148405740'), ('ANK2', 'rs730880049'), ('ANKRD1', 'rs869025363'), ('CACNA1C', 'rs1057518456'), ('CACNA1C', 'rs111442547'), ('CACNA1C', 'rs111606207'), ('CACNA1C', 'rs112170830'), ('CACNA1C', 'rs121912775'), ('CACNA1C', 'rs12828687'), ('CACNA1C', 'rs142476147'), ('CACNA1C', 'rs186015395'), ('CACNA1C', 'rs186708407'), ('CACNA1C', 'rs186741807'), ('CACNA1C', 'rs199473391'), ('CACNA1C', 'rs199473392'), ('CACNA1C', 'rs199473660'), ('CACNA1C', 'rs199538058'), ('CACNA1C', 'rs199694744'), ('CACNA1C', 'rs200231105'), ('CACNA1C', 'rs200588235'), ('CACNA1C', 'rs201258230'), ('CACNA1C', 'rs201492706'), ('CACNA1C', 'rs201756421'), ('CACNA1C', 'rs367895193'), ('CACNA1C', 'rs369267978'), ('CACNA1C', 'rs369438564'), ('CACNA1C', 'rs369673473'), ('CACNA1C', 'rs370145265'), ('CACNA1C', 'rs370630496'), ('CACNA1C', 'rs374857905'), ('CACNA1C', 'rs375818733'), ('CACNA1C', 'rs376987352'), ('CACNA1C', 'rs377165829'), ('CACNA1C', 'rs533634115'), ('CACNA1C', 'rs545511851'), ('CACNA1C', 'rs547615657'), ('CACNA1C', 'rs555721726'), ('CACNA1C', 'rs561365937'), ('CACNA1C', 'rs563090568'), ('CACNA1C', 'rs56394008'), ('CACNA1C', 'rs567401056'), ('CACNA1C', 'rs748926089'), ('CACNA1C', 'rs749753216'), ('CACNA1C', 'rs751166285'), ('CACNA1C', 'rs752000790'), ('CACNA1C', 'rs752736296'), ('CACNA1C', 'rs753892795'), ('CACNA1C', 'rs755167125'), ('CACNA1C', 'rs755579963'), ('CACNA1C', 'rs756364065'), ('CACNA1C', 'rs757966245'), ('CACNA1C', 'rs758461435'), ('CACNA1C', 'rs760888275'), ('CACNA1C', 'rs762376206'), ('CACNA1C', 'rs763622598'), ('CACNA1C', 'rs764323907'), ('CACNA1C', 'rs767190987'), ('CACNA1C', 'rs768270021'), ('CACNA1C', 'rs768830617'), ('CACNA1C', 'rs773930851'), ('CACNA1C', 'rs774165526'), ('CACNA1C', 'rs774490908'), ('CACNA1C', 'rs775331521'), ('CACNA1C', 'rs776522592'), ('CACNA1C', 'rs778220127'), ('CACNA1C', 'rs779009338'), ('CACNA1C', 'rs779194497'), ('CACNA1C', 'rs781395450'), ('CACNA1C', 'rs886038918'), ('CACNA1C', 'rs886039214'), ('CACNA1C', 'rs886049148'), ('CACNA1C', 'rs886049149'), ('CACNA1C', 'rs886049150'), ('CACNA1C', 'rs886049202'), ('CACNA1C', 'rs886049203'), ('CACNA1C', 'rs886049204'), ('CACNA1C', 'rs886049205'), ('CACNA1C', 'rs886049206'), ('CACNA1C', 'rs886049207'), ('CACNA1C', 'rs886049208'), ('CACNA1C', 'rs886049209'), ('CACNA1C', 'rs886049210'), ('CACNA1C', 'rs886049211'), ('CACNA1C', 'rs886049212'), ('CACNA1C', 'rs886049213'), ('CACNA1C', 'rs886049214'), ('CACNA1C', 'rs886049216'), ('CACNA1C', 'rs886049217'), ('CACNA1C', 'rs886049218'), ('CACNA1C', 'rs886049219'), ('CACNA1C', 'rs886049221'), ('CACNA1C', 'rs886049222'), ('CACNA1C', 'rs886049223'), ('CACNA1C', 'rs886049224'), ('CACNA1C', 'rs886049225'), ('CACNA1C', 'rs886049226'), ('CACNA1C', 'rs886049227'), ('CACNA1C', 'rs886049228'), ('CACNA1C', 'rs886049229'), ('CACNA1C', 'rs886049230'), ('CACNA1C', 'rs886049231'), ('CACNA1C', 'rs886049232'), ('CACNA1C', 'rs886049233'), ('CACNA1C', 'rs886049234'), ('CACNA1C', 'rs886049235'), ('CACNA1C', 'rs886049236'), ('CACNA1C', 'rs886049237'), ('CACNA1C', 'rs886049238'), ('CACNA1C', 'rs886049239'), ('CACNA1C', 'rs886049240'), ('CACNA1C', 'rs886049241'), ('CACNA1C', 'rs886049243'), ('CACNA1C', 'rs886049244'), ('CACNA1C', 'rs886049245'), ('CACNA1C', 'rs886049246'), ('CACNA1C', 'rs886049247'), ('CACNA1C', 'rs886049248'), ('CACNA1C', 'rs886049249'), ('CACNA1C', 'rs886049250'), ('CACNA1C', 'rs886049251'), ('CACNA1C-AS1', 'rs200231105'), ('CACNA2D1', 'rs1060503151'), ('CACNA2D1', 'rs1163800062'), ('CACNA2D1', 'rs1218449046'), ('CACNA2D1', 'rs139608070'), ('CACNA2D1', 'rs141238313'), ('CACNA2D1', 'rs1477267428'), ('CACNA2D1', 'rs1554327285'), ('CACNA2D1', 'rs1554333986'), ('CACNA2D1', 'rs1554345090'), ('CACNA2D1', 'rs1554349582'), ('CACNA2D1', 'rs1554398187'), ('CACNA2D1', 'rs1554560384'), ('CACNA2D1', 'rs192741898'), ('CACNA2D1', 'rs201682618'), ('CACNA2D1', 'rs202108848'), ('CACNA2D1', 'rs368512946'), ('CACNA2D1', 'rs745501384'), ('CACNA2D1', 'rs756765026'), ('CACNA2D1', 'rs757313687'), ('CACNA2D1', 'rs771243374'), ('CACNA2D1', 'rs773095610'), ('CACNA2D1', 'rs780901801'), ('CACNA2D1', 'rs869025369'), ('CACNB2', 'rs1064795457'), ('CACNB2', 'rs111250176'), ('CACNB2', 'rs137886839'), ('CACNB2', 'rs138423466'), ('CACNB2', 'rs143326262'), ('CACNB2', 'rs144182966'), ('CACNB2', 'rs144509796'), ('CACNB2', 'rs149253719'), ('CACNB2', 'rs149793143'), ('CACNB2', 'rs150280879'), ('CACNB2', 'rs150528041'), ('CACNB2', 'rs151199943'), ('CACNB2', 'rs1554843746'), ('CACNB2', 'rs182163363'), ('CACNB2', 'rs182634399'), ('CACNB2', 'rs187815725'), ('CACNB2', 'rs191106518'), ('CACNB2', 'rs192508010'), ('CACNB2', 'rs200654601'), ('CACNB2', 'rs202152674'), ('CACNB2', 'rs34551674'), ('CACNB2', 'rs367928065'), ('CACNB2', 'rs368719191'), ('CACNB2', 'rs373932682'), ('CACNB2', 'rs376222853'), ('CACNB2', 'rs528559406'), ('CACNB2', 'rs536419495'), ('CACNB2', 'rs543872505'), ('CACNB2', 'rs546669133'), ('CACNB2', 'rs547804393'), ('CACNB2', 'rs551293049'), ('CACNB2', 'rs562896922'), ('CACNB2', 'rs564275776'), ('CACNB2', 'rs564407056'), ('CACNB2', 'rs568890834'), ('CACNB2', 'rs568986179'), ('CACNB2', 'rs61733968'), ('CACNB2', 'rs745337273'), ('CACNB2', 'rs750396182'), ('CACNB2', 'rs752637408'), ('CACNB2', 'rs753335762'), ('CACNB2', 'rs758274878'), ('CACNB2', 'rs759258778'), ('CACNB2', 'rs764843384'), ('CACNB2', 'rs76956014'), ('CACNB2', 'rs773767571'), ('CACNB2', 'rs775466397'), ('CACNB2', 'rs775896337'), ('CACNB2', 'rs778295363'), ('CACNB2', 'rs780734976'), ('CACNB2', 'rs781283574'), ('CACNB2', 'rs78378025'), ('CACNB2', 'rs875989812'), ('CACNB2', 'rs886046883'), ('CACNB2', 'rs886046884'), ('CACNB2', 'rs886046885'), ('CACNB2', 'rs886046886'), ('CACNB2', 'rs886046887'), ('CACNB2', 'rs886046891'), ('CACNB2', 'rs886046892'), ('CACNB2', 'rs886046893'), ('CACNB2', 'rs886046894'), ('CACNB2', 'rs886046896'), ('CACNB2', 'rs886046897'), ('CACNB2', 'rs886046898'), ('CACNB2', 'rs886046899'), ('CACNB2', 'rs886046901'), ('CACNB2', 'rs886046902'), ('CACNB2', 'rs886046906'), ('CACNB2', 'rs886046907'), ('CACNB2', 'rs886046908'), ('COL5A1', 'rs1564417691'), ('GPD1L', 'rs112122950'), ('GPD1L', 'rs112185839'), ('GPD1L', 'rs113764055'), ('GPD1L', 'rs114349261'), ('GPD1L', 'rs115291555'), ('GPD1L', 'rs116281194'), ('GPD1L', 'rs1216770303'), ('GPD1L', 'rs1376727184'), ('GPD1L', 'rs139494055'), ('GPD1L', 'rs140250795'), ('GPD1L', 'rs143486835'), ('GPD1L', 'rs144925784'), ('GPD1L', 'rs148361833'), ('GPD1L', 'rs148464224'), ('GPD1L', 'rs149641866'), ('GPD1L', 'rs1553659648'), ('GPD1L', 'rs1553660781'), ('GPD1L', 'rs1559565644'), ('GPD1L', 'rs1559579249'), ('GPD1L', 'rs182826539'), ('GPD1L', 'rs186019566'), ('GPD1L', 'rs201799095'), ('GPD1L', 'rs373602669'), ('GPD1L', 'rs531920801'), ('GPD1L', 'rs537616228'), ('GPD1L', 'rs538672341'), ('GPD1L', 'rs546574502'), ('GPD1L', 'rs558257162'), ('GPD1L', 'rs566007803'), ('GPD1L', 'rs72546642'), ('GPD1L', 'rs72546651'), ('GPD1L', 'rs72552292'), ('GPD1L', 'rs72552294'), ('GPD1L', 'rs72558074'), ('GPD1L', 'rs755306391'), ('GPD1L', 'rs757146653'), ('GPD1L', 'rs757614405'), ('GPD1L', 'rs757638347'), ('GPD1L', 'rs759080305'), ('GPD1L', 'rs772985306'), ('GPD1L', 'rs777110449'), ('GPD1L', 'rs786204216'), ('GPD1L', 'rs786205268'), ('GPD1L', 'rs878855004'), ('GPD1L', 'rs886058331'), ('GPD1L', 'rs886058332'), ('GPD1L', 'rs886058333'), ('GPD1L', 'rs886058334'), ('GPD1L', 'rs886058335'), ('GPD1L', 'rs886058336'), ('GPD1L', 'rs886058337'), ('GPD1L', 'rs886058338'), ('HCN4', 'rs560874115'), ('HCN4', 'rs764493888'), ('KCND3', 'rs869025444'), ('KCNE1', 'rs74315445'), ('KCNE3', 'rs113583236'), ('KCNE3', 'rs121908441'), ('KCNE3', 'rs150406522'), ('KCNE3', 'rs182905404'), ('KCNE3', 'rs187700411'), ('KCNE3', 'rs191005723'), ('KCNE3', 'rs201843136'), ('KCNE3', 'rs41258394'), ('KCNE3', 'rs41315539'), ('KCNE3', 'rs41315541'), ('KCNE3', 'rs528760350'), ('KCNE3', 'rs529326016'), ('KCNE3', 'rs535500151'), ('KCNE3', 'rs540669024'), ('KCNE3', 'rs546242304'), ('KCNE3', 'rs549819195'), ('KCNE3', 'rs555082306'), ('KCNE3', 'rs566273812'), ('KCNE3', 'rs569357069'), ('KCNE3', 'rs570472222'), ('KCNE3', 'rs60016728'), ('KCNE3', 'rs72552105'), ('KCNE3', 'rs745623708'), ('KCNE3', 'rs753304260'), ('KCNE3', 'rs758082514'), ('KCNE3', 'rs764717543'), ('KCNE3', 'rs867623173'), ('KCNE3', 'rs886048645'), ('KCNE3', 'rs886048646'), ('KCNE3', 'rs886048647'), ('KCNE3', 'rs886048648'), ('KCNE3', 'rs886048650'), ('KCNE3', 'rs886048651'), ('KCNE3', 'rs886048652'), ('KCNE3', 'rs886048653'), ('KCNE3', 'rs886048654'), ('KCNE5', 'rs1420621771'), ('KCNE5', 'rs375008004'), ('KCNE5', 'rs764993726'), ('KCNJ8', 'rs117808169'), ('KCNJ8', 'rs149127157'), ('KCNJ8', 'rs1555172510'), ('KCNJ8', 'rs1565662161'), ('KCNJ8', 'rs730880120'), ('KCNQ1', 'rs775608046'), ('MYBPC3', 'rs397515985'), ('PKP2', 'rs146882581'), ('PKP2', 'rs149930872'), ('SCN10A', 'rs1060501715'), ('SCN10A', 'rs1060501716'), ('SCN10A', 'rs1060501717'), ('SCN10A', 'rs1167279918'), ('SCN10A', 'rs1173154320'), ('SCN10A', 'rs1199205585'), ('SCN10A', 'rs1226072923'), ('SCN10A', 'rs1265687114'), ('SCN10A', 'rs1334180362'), ('SCN10A', 'rs1334461772'), ('SCN10A', 'rs1372622252'), ('SCN10A', 'rs1373914068'), ('SCN10A', 'rs138404783'), ('SCN10A', 'rs138832868'), ('SCN10A', 'rs139638446'), ('SCN10A', 'rs1397301108'), ('SCN10A', 'rs139861061'), ('SCN10A', 'rs140288103'), ('SCN10A', 'rs140825889'), ('SCN10A', 'rs141368548'), ('SCN10A', 'rs141810266'), ('SCN10A', 'rs142203439'), ('SCN10A', 'rs142235256'), ('SCN10A', 'rs142276689'), ('SCN10A', 'rs142884499'), ('SCN10A', 'rs143744796'), ('SCN10A', 'rs1450059546'), ('SCN10A', 'rs145032037'), ('SCN10A', 'rs145694222'), ('SCN10A', 'rs145712124'), ('SCN10A', 'rs146965005'), ('SCN10A', 'rs147844607'), ('SCN10A', 'rs148537653'), ('SCN10A', 'rs148663098'), ('SCN10A', 'rs149155352'), ('SCN10A', 'rs149504103'), ('SCN10A', 'rs150923753'), ('SCN10A', 'rs151303346'), ('SCN10A', 'rs1553612991'), ('SCN10A', 'rs1553613078'), ('SCN10A', 'rs1553614805'), ('SCN10A', 'rs1553616744'), ('SCN10A', 'rs1553619005'), ('SCN10A', 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('SCN10A', 'rs375940680'), ('SCN10A', 'rs377492327'), ('SCN10A', 'rs539215014'), ('SCN10A', 'rs542554745'), ('SCN10A', 'rs553784643'), ('SCN10A', 'rs569261408'), ('SCN10A', 'rs746690639'), ('SCN10A', 'rs747044382'), ('SCN10A', 'rs747174454'), ('SCN10A', 'rs747296872'), ('SCN10A', 'rs747321219'), ('SCN10A', 'rs747486328'), ('SCN10A', 'rs747839312'), ('SCN10A', 'rs747848559'), ('SCN10A', 'rs748441157'), ('SCN10A', 'rs748854017'), ('SCN10A', 'rs750073618'), ('SCN10A', 'rs751252167'), ('SCN10A', 'rs752623537'), ('SCN10A', 'rs754130748'), ('SCN10A', 'rs755100226'), ('SCN10A', 'rs756133876'), ('SCN10A', 'rs756253735'), ('SCN10A', 'rs756547221'), ('SCN10A', 'rs757916036'), ('SCN10A', 'rs758157003'), ('SCN10A', 'rs759136534'), ('SCN10A', 'rs759842238'), ('SCN10A', 'rs762600386'), ('SCN10A', 'rs762798134'), ('SCN10A', 'rs764965507'), ('SCN10A', 'rs766017851'), ('SCN10A', 'rs766143752'), ('SCN10A', 'rs772484960'), ('SCN10A', 'rs774893568'), ('SCN10A', 'rs777258179'), ('SCN10A', 'rs779316495'), ('SCN10A', 'rs781354273'), ('SCN10A', 'rs910678839'), ('SCN1B', 'rs147073518'), ('SCN1B', 'rs72552027'), ('SCN1B', 'rs72558029'), ('SCN1B', 'rs886054339'), ('SCN1B', 'rs886054340'), ('SCN1B', 'rs886054341'), ('SCN3B', 'rs111341342'), ('SCN3B', 'rs114709124'), ('SCN3B', 'rs116885934'), ('SCN3B', 'rs117409744'), ('SCN3B', 'rs138774330'), ('SCN3B', 'rs139934383'), ('SCN3B', 'rs144520035'), ('SCN3B', 'rs148244106'), ('SCN3B', 'rs184556043'), ('SCN3B', 'rs187400761'), ('SCN3B', 'rs370826688'), ('SCN3B', 'rs543489443'), ('SCN3B', 'rs544984224'), ('SCN3B', 'rs547303769'), ('SCN3B', 'rs553042856'), ('SCN3B', 'rs555303241'), ('SCN3B', 'rs558085329'), ('SCN3B', 'rs577244366'), ('SCN3B', 'rs72552139'), ('SCN3B', 'rs72552158'), ('SCN3B', 'rs72552164'), ('SCN3B', 'rs72552185'), ('SCN3B', 'rs72552191'), ('SCN3B', 'rs72552193'), ('SCN3B', 'rs72552194'), ('SCN3B', 'rs72552195'), ('SCN3B', 'rs72553906'), ('SCN3B', 'rs72553907'), ('SCN3B', 'rs72553909'), ('SCN3B', 'rs748097809'), ('SCN3B', 'rs751005040'), ('SCN3B', 'rs753258598'), ('SCN3B', 'rs758175811'), ('SCN3B', 'rs75996884'), ('SCN3B', 'rs76257004'), ('SCN3B', 'rs765294617'), ('SCN3B', 'rs77584352'), ('SCN3B', 'rs776449566'), ('SCN3B', 'rs80017720'), ('SCN3B', 'rs867302682'), ('SCN3B', 'rs886047884'), ('SCN3B', 'rs886047885'), ('SCN3B', 'rs886047886'), ('SCN3B', 'rs886047887'), ('SCN3B', 'rs886047888'), ('SCN3B', 'rs886047889'), ('SCN3B', 'rs886047890'), ('SCN3B', 'rs886047891'), ('SCN3B', 'rs886047892'), ('SCN3B', 'rs886047893'), ('SCN3B', 'rs886047894'), ('SCN3B', 'rs886047895'), ('SCN3B', 'rs886047897'), ('SCN3B', 'rs886047898'), ('SCN3B', 'rs886047899'), ('SCN3B', 'rs886047900'), ('SCN3B', 'rs886047901'), ('SCN3B', 'rs886047902'), ('SCN3B', 'rs886047903'), ('SCN3B', 'rs886047904'), ('SCN3B', 'rs886047905'), ('SCN3B', 'rs886047906'), ('SCN3B', 'rs886047907'), ('SCN5A', 'rs1011460663'), ('SCN5A', 'rs1038605800'), ('SCN5A', 'rs1060499900'), ('SCN5A', 'rs1060501126'), ('SCN5A', 'rs1060501128'), ('SCN5A', 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('SCN5A', 'rs199473089'), ('SCN5A', 'rs199473094'), ('SCN5A', 'rs199473100'), ('SCN5A', 'rs199473110'), ('SCN5A', 'rs199473111'), ('SCN5A', 'rs199473112'), ('SCN5A', 'rs199473113'), ('SCN5A', 'rs199473116'), ('SCN5A', 'rs199473118'), ('SCN5A', 'rs199473119'), ('SCN5A', 'rs199473121'), ('SCN5A', 'rs199473123'), ('SCN5A', 'rs199473125'), ('SCN5A', 'rs199473126'), ('SCN5A', 'rs199473128'), ('SCN5A', 'rs199473129'), ('SCN5A', 'rs199473141'), ('SCN5A', 'rs199473145'), ('SCN5A', 'rs199473146'), ('SCN5A', 'rs199473151'), ('SCN5A', 'rs199473163'), ('SCN5A', 'rs199473166'), ('SCN5A', 'rs199473177'), ('SCN5A', 'rs199473182'), ('SCN5A', 'rs199473185'), ('SCN5A', 'rs199473186'), ('SCN5A', 'rs199473187'), ('SCN5A', 'rs199473189'), ('SCN5A', 'rs199473192'), ('SCN5A', 'rs199473195'), ('SCN5A', 'rs199473196'), ('SCN5A', 'rs199473197'), ('SCN5A', 'rs199473198'), ('SCN5A', 'rs199473209'), ('SCN5A', 'rs199473218'), ('SCN5A', 'rs199473224'), ('SCN5A', 'rs199473226'), ('SCN5A', 'rs199473238'), ('SCN5A', 'rs199473243'), ('SCN5A', 'rs199473258'), ('SCN5A', 'rs199473260'), ('SCN5A', 'rs199473263'), ('SCN5A', 'rs199473265'), ('SCN5A', 'rs199473272'), ('SCN5A', 'rs199473278'), ('SCN5A', 'rs199473284'), ('SCN5A', 'rs199473286'), ('SCN5A', 'rs199473288'), ('SCN5A', 'rs199473296'), ('SCN5A', 'rs199473303'), ('SCN5A', 'rs199473310'), ('SCN5A', 'rs199473313'), ('SCN5A', 'rs199473314'), ('SCN5A', 'rs199473325'), ('SCN5A', 'rs199473328'), ('SCN5A', 'rs199473330'), ('SCN5A', 'rs199473331'), ('SCN5A', 'rs199473332'), ('SCN5A', 'rs199473333'), ('SCN5A', 'rs199473335'), ('SCN5A', 'rs199473336'), ('SCN5A', 'rs199473339'), ('SCN5A', 'rs199473340'), ('SCN5A', 'rs199473341'), ('SCN5A', 'rs199473550'), ('SCN5A', 'rs199473552'), ('SCN5A', 'rs199473555'), ('SCN5A', 'rs199473571'), ('SCN5A', 'rs199473572'), ('SCN5A', 'rs199473575'), ('SCN5A', 'rs199473578'), ('SCN5A', 'rs199473590'), ('SCN5A', 'rs199473595'), ('SCN5A', 'rs199473598'), ('SCN5A', 'rs199473600'), ('SCN5A', 'rs199473602'), ('SCN5A', 'rs199473603'), ('SCN5A', 'rs199473606'), ('SCN5A', 'rs199473607'), ('SCN5A', 'rs199473630'), ('SCN5A', 'rs199473635'), ('SCN5A', 'rs199473638'), ('SCN5A', 'rs199473640'), ('SCN5A', 'rs199473641'), ('SCN5A', 'rs200034939'), ('SCN5A', 'rs200569112'), ('SCN5A', 'rs200868190'), ('SCN5A', 'rs201276017'), ('SCN5A', 'rs201641342'), ('SCN5A', 'rs202114798'), ('SCN5A', 'rs36210420'), ('SCN5A', 'rs367807565'), ('SCN5A', 'rs367906630'), ('SCN5A', 'rs368048551'), ('SCN5A', 'rs368058564'), ('SCN5A', 'rs368357262'), ('SCN5A', 'rs368678204'), ('SCN5A', 'rs369058100'), ('SCN5A', 'rs369565476'), ('SCN5A', 'rs369678002'), ('SCN5A', 'rs369704754'), ('SCN5A', 'rs370114378'), ('SCN5A', 'rs370346797'), ('SCN5A', 'rs370588133'), ('SCN5A', 'rs370694515'), ('SCN5A', 'rs371308670'), ('SCN5A', 'rs371313714'), ('SCN5A', 'rs373118001'), ('SCN5A', 'rs373156650'), ('SCN5A', 'rs373410109'), ('SCN5A', 'rs374314562'), ('SCN5A', 'rs375306544'), ('SCN5A', 'rs375323548'), ('SCN5A', 'rs375614054'), ('SCN5A', 'rs376697724'), ('SCN5A', 'rs376965389'), ('SCN5A', 'rs397514450'), ('SCN5A', 'rs397517951'), ('SCN5A', 'rs397517953'), ('SCN5A', 'rs397517956'), ('SCN5A', 'rs41276525'), ('SCN5A', 'rs41310753'), ('SCN5A', 'rs41310765'), ('SCN5A', 'rs41310769'), ('SCN5A', 'rs41311121'), ('SCN5A', 'rs41311135'), ('SCN5A', 'rs41312419'), ('SCN5A', 'rs41313015'), ('SCN5A', 'rs41313033'), ('SCN5A', 'rs41313667'), ('SCN5A', 'rs41313687'), ('SCN5A', 'rs41313693'), ('SCN5A', 'rs41313703'), ('SCN5A', 'rs41315489'), ('SCN5A', 'rs45437099'), ('SCN5A', 'rs45458203'), ('SCN5A', 'rs45459402'), ('SCN5A', 'rs45465995'), ('SCN5A', 'rs45475899'), ('SCN5A', 'rs45489199'), ('SCN5A', 'rs45491996'), ('SCN5A', 'rs45502793'), ('SCN5A', 'rs45503498'), ('SCN5A', 'rs45522138'), ('SCN5A', 'rs45553235'), ('SCN5A', 'rs45563942'), ('SCN5A', 'rs527480102'), ('SCN5A', 'rs536201762'), ('SCN5A', 'rs538707712'), ('SCN5A', 'rs540984871'), ('SCN5A', 'rs546849670'), ('SCN5A', 'rs551399685'), ('SCN5A', 'rs560476223'), ('SCN5A', 'rs561475141'), ('SCN5A', 'rs561547165'), ('SCN5A', 'rs561922849'), ('SCN5A', 'rs566251672'), ('SCN5A', 'rs569249327'), ('SCN5A', 'rs569552176'), ('SCN5A', 'rs575883763'), ('SCN5A', 'rs587781157'), ('SCN5A', 'rs587781159'), ('SCN5A', 'rs61737825'), ('SCN5A', 'rs72549411'), ('SCN5A', 'rs727504495'), ('SCN5A', 'rs727504822'), ('SCN5A', 'rs730880207'), ('SCN5A', 'rs730880208'), ('SCN5A', 'rs730880211'), ('SCN5A', 'rs746291609'), ('SCN5A', 'rs746360906'), ('SCN5A', 'rs747251132'), ('SCN5A', 'rs748297358'), ('SCN5A', 'rs749769938'), ('SCN5A', 'rs751050999'), ('SCN5A', 'rs752824646'), ('SCN5A', 'rs753149586'), ('SCN5A', 'rs753835985'), ('SCN5A', 'rs755162776'), ('SCN5A', 'rs755194086'), ('SCN5A', 'rs755980331'), ('SCN5A', 'rs756474485'), ('SCN5A', 'rs757119370'), ('SCN5A', 'rs757302500'), ('SCN5A', 'rs757532106'), ('SCN5A', 'rs758101066'), ('SCN5A', 'rs758282196'), ('SCN5A', 'rs758959053'), ('SCN5A', 'rs759036311'), ('SCN5A', 'rs759584454'), ('SCN5A', 'rs75960619'), ('SCN5A', 'rs760011764'), ('SCN5A', 'rs760016062'), ('SCN5A', 'rs760585484'), ('SCN5A', 'rs760837591'), ('SCN5A', 'rs761117662'), ('SCN5A', 'rs761369505'), ('SCN5A', 'rs761505485'), ('SCN5A', 'rs762012668'), ('SCN5A', 'rs762283891'), ('SCN5A', 'rs762818132'), ('SCN5A', 'rs762981322'), ('SCN5A', 'rs763550164'), ('SCN5A', 'rs763830252'), ('SCN5A', 'rs763880032'), ('SCN5A', 'rs763891399'), ('SCN5A', 'rs764252430'), ('SCN5A', 'rs764488677'), ('SCN5A', 'rs765907469'), ('SCN5A', 'rs767116750'), ('SCN5A', 'rs768246863'), ('SCN5A', 'rs768691853'), ('SCN5A', 'rs769473892'), ('SCN5A', 'rs770088052'), ('SCN5A', 'rs770390440'), ('SCN5A', 'rs771018427'), ('SCN5A', 'rs771243543'), ('SCN5A', 'rs772186966'), ('SCN5A', 'rs772258197'), ('SCN5A', 'rs772585696'), ('SCN5A', 'rs773016454'), ('SCN5A', 'rs773422233'), ('SCN5A', 'rs774432823'), ('SCN5A', 'rs774593360'), ('SCN5A', 'rs775485359'), ('SCN5A', 'rs776171341'), ('SCN5A', 'rs776705132'), ('SCN5A', 'rs776925980'), ('SCN5A', 'rs776980213'), ('SCN5A', 'rs777061524'), ('SCN5A', 'rs778236407'), ('SCN5A', 'rs778522112'), ('SCN5A', 'rs779649600'), ('SCN5A', 'rs779669888'), ('SCN5A', 'rs779953279'), ('SCN5A', 'rs779999584'), ('SCN5A', 'rs780405533'), ('SCN5A', 'rs780761880'), ('SCN5A', 'rs781103369'), ('SCN5A', 'rs781104838'), ('SCN5A', 'rs781529391'), ('SCN5A', 'rs786205271'), ('SCN5A', 'rs794728842'), ('SCN5A', 'rs794728852'), ('SCN5A', 'rs794728853'), ('SCN5A', 'rs794728855'), ('SCN5A', 'rs794728869'), ('SCN5A', 'rs794728875'), ('SCN5A', 'rs794728883'), ('SCN5A', 'rs794728898'), ('SCN5A', 'rs794728899'), ('SCN5A', 'rs794728910'), ('SCN5A', 'rs794728916'), ('SCN5A', 'rs794728925'), ('SCN5A', 'rs794728927'), ('SCN5A', 'rs794728934'), ('SCN5A', 'rs794728935'), ('SCN5A', 'rs794728940'), ('SCN5A', 'rs863224816'), ('SCN5A', 'rs864622440'), ('SCN5A', 'rs865884072'), ('SCN5A', 'rs869025517'), ('SCN5A', 'rs878855288'), ('SCN5A', 'rs878855289'), ('SCN5A', 'rs878855292'), ('SCN5A', 'rs878855294'), ('SCN5A', 'rs878855295'), ('SCN5A', 'rs878855296'), ('SCN5A', 'rs878911306'), ('SCN5A', 'rs879035421'), ('SCN5A', 'rs879255356'), ('SCN5A', 'rs886058437'), ('SCN5A', 'rs886058438'), ('SCN5A', 'rs886058439'), ('SCN5A', 'rs886058440'), ('SCN5A', 'rs886058441'), ('SCN5A', 'rs886058442'), ('SCN5A', 'rs886058443'), ('SCN5A', 'rs886058444'), ('SCN5A', 'rs886058445'), ('SCN5A', 'rs886058446'), ('SCN5A', 'rs886058447'), ('SCN5A', 'rs886058448'), ('SCN5A', 'rs886058449'), ('SCN5A', 'rs886058450'), ('SCN5A', 'rs886058451'), ('SCN5A', 'rs886058452'), ('SCN5A', 'rs886058453'), ('SCN5A', 'rs886058454'), ('SCN5A', 'rs886058455'), ('SCN5A', 'rs886058456'), ('SCN5A', 'rs886058457'), ('SCN5A', 'rs886058458'), ('SCN5A', 'rs886058459'), ('SCN5A', 'rs886058460'), ('SCN5A', 'rs886058461'), ('SCN5A', 'rs886058462'), ('SCN5A', 'rs886058463'), ('SCN5A', 'rs886058464'), ('SCN5A', 'rs886058465'), ('SCN5A', 'rs886058466'), ('SCN5A', 'rs918933961'), ('SCN5A', 'rs949932623'), ('SCN5A', 'rs9858585'), ('SLMAP', 'rs1016820088'), ('SLMAP', 'rs1060503190'), ('SLMAP', 'rs140490085'), ('SLMAP', 'rs142516364'), ('SLMAP', 'rs142778041'), ('SLMAP', 'rs149548827'), ('SLMAP', 'rs150439110'), ('SLMAP', 'rs746146243'), ('SLMAP', 'rs750893840'), ('SLMAP', 'rs751083292'), ('SLMAP', 'rs754387957'), ('SLMAP', 'rs763740777'), ('SLMAP', 'rs901233405'), ('SNTA1', 'rs137986136'), ('TCAP', 'rs146906267'), ('TRPM4', 'rs172149856'), ('TRPM4', 'rs201907325'), ('TRPM4', 'rs201994425'), ('TRPM4', 'rs747192078'), ('TRPM4', 'rs878855029'), ('TTN', 'rs148067743'), ('TTN', 'rs368327166'), ('TTN', 'rs55980498'), ('TTN', 'rs72646873'), ('TTN', 'rs72648942'), ('TTN', 'rs72650031'), ('TTN', 'rs761362832'), ('TTR', 'rs745834030')]
0 variants in opentargets and not in disgenet: []
290 variants in disgenet and not in opentargets: [('CACNA1C', 'rs121912776'), ('CACNA1C', 'rs765116077'), ('GPD1L', 'rs72552291'), ('KCNH2', 'rs12720441'), ('KCNH2', 'rs199473547'), ('KCNJ8', 'rs72554071'), ('NOS1AP', 'rs10494366'), ('RANGRF', 'rs751751942'), ('SCN10A', 'rs10428132'), ('SCN2B', 'rs587777023'), ('SCN3B', 'rs121918282'), ('SCN3B', 'rs147205617'), ('SCN5A', 'rs1060501114'), ('SCN5A', 'rs1060501127'), ('SCN5A', 'rs1060501130'), ('SCN5A', 'rs1060501135'), ('SCN5A', 'rs1060501136'), ('SCN5A', 'rs1060501142'), ('SCN5A', 'rs1060501145'), ('SCN5A', 'rs1064792926'), ('SCN5A', 'rs1131691708'), ('SCN5A', 'rs11708996'), ('SCN5A', 'rs12720452'), ('SCN5A', 'rs137854600'), ('SCN5A', 'rs137854601'), ('SCN5A', 'rs137854602'), ('SCN5A', 'rs137854603'), ('SCN5A', 'rs137854604'), ('SCN5A', 'rs137854606'), ('SCN5A', 'rs137854607'), ('SCN5A', 'rs137854609'), ('SCN5A', 'rs137854611'), ('SCN5A', 'rs137854612'), ('SCN5A', 'rs137854614'), ('SCN5A', 'rs137854615'), ('SCN5A', 'rs137854616'), ('SCN5A', 'rs137854617'), ('SCN5A', 'rs137854618'), ('SCN5A', 'rs1805124'), ('SCN5A', 'rs185492581'), ('SCN5A', 'rs185638763'), ('SCN5A', 'rs193922726'), ('SCN5A', 'rs199473045'), ('SCN5A', 'rs199473050'), ('SCN5A', 'rs199473051'), ('SCN5A', 'rs199473052'), ('SCN5A', 'rs199473053'), ('SCN5A', 'rs199473054'), ('SCN5A', 'rs199473055'), ('SCN5A', 'rs199473056'), ('SCN5A', 'rs199473058'), ('SCN5A', 'rs199473061'), ('SCN5A', 'rs199473062'), ('SCN5A', 'rs199473063'), ('SCN5A', 'rs199473065'), ('SCN5A', 'rs199473066'), ('SCN5A', 'rs199473067'), ('SCN5A', 'rs199473070'), ('SCN5A', 'rs199473072'), ('SCN5A', 'rs199473074'), ('SCN5A', 'rs199473076'), ('SCN5A', 'rs199473079'), ('SCN5A', 'rs199473081'), ('SCN5A', 'rs199473082'), ('SCN5A', 'rs199473083'), ('SCN5A', 'rs199473086'), ('SCN5A', 'rs199473088'), ('SCN5A', 'rs199473090'), ('SCN5A', 'rs199473091'), ('SCN5A', 'rs199473092'), ('SCN5A', 'rs199473093'), ('SCN5A', 'rs199473095'), ('SCN5A', 'rs199473096'), ('SCN5A', 'rs199473097'), ('SCN5A', 'rs199473098'), ('SCN5A', 'rs199473101'), ('SCN5A', 'rs199473102'), ('SCN5A', 'rs199473103'), ('SCN5A', 'rs199473104'), ('SCN5A', 'rs199473117'), ('SCN5A', 'rs199473122'), ('SCN5A', 'rs199473124'), ('SCN5A', 'rs199473133'), ('SCN5A', 'rs199473134'), ('SCN5A', 'rs199473137'), ('SCN5A', 'rs199473139'), ('SCN5A', 'rs199473143'), ('SCN5A', 'rs199473144'), ('SCN5A', 'rs199473147'), ('SCN5A', 'rs199473149'), ('SCN5A', 'rs199473153'), ('SCN5A', 'rs199473154'), ('SCN5A', 'rs199473156'), ('SCN5A', 'rs199473157'), ('SCN5A', 'rs199473158'), ('SCN5A', 'rs199473159'), ('SCN5A', 'rs199473160'), ('SCN5A', 'rs199473161'), ('SCN5A', 'rs199473164'), ('SCN5A', 'rs199473167'), ('SCN5A', 'rs199473168'), ('SCN5A', 'rs199473169'), ('SCN5A', 'rs199473170'), ('SCN5A', 'rs199473171'), ('SCN5A', 'rs199473172'), ('SCN5A', 'rs199473173'), ('SCN5A', 'rs199473174'), ('SCN5A', 'rs199473175'), ('SCN5A', 'rs199473176'), ('SCN5A', 'rs199473178'), ('SCN5A', 'rs199473179'), ('SCN5A', 'rs199473180'), ('SCN5A', 'rs199473181'), ('SCN5A', 'rs199473188'), ('SCN5A', 'rs199473194'), ('SCN5A', 'rs199473199'), ('SCN5A', 'rs199473204'), ('SCN5A', 'rs199473205'), ('SCN5A', 'rs199473206'), ('SCN5A', 'rs199473207'), ('SCN5A', 'rs199473208'), ('SCN5A', 'rs199473210'), ('SCN5A', 'rs199473211'), ('SCN5A', 'rs199473213'), ('SCN5A', 'rs199473214'), ('SCN5A', 'rs199473217'), ('SCN5A', 'rs199473219'), ('SCN5A', 'rs199473220'), ('SCN5A', 'rs199473221'), ('SCN5A', 'rs199473225'), ('SCN5A', 'rs199473228'), ('SCN5A', 'rs199473229'), ('SCN5A', 'rs199473230'), ('SCN5A', 'rs199473231'), ('SCN5A', 'rs199473232'), ('SCN5A', 'rs199473233'), ('SCN5A', 'rs199473234'), ('SCN5A', 'rs199473235'), ('SCN5A', 'rs199473236'), ('SCN5A', 'rs199473237'), ('SCN5A', 'rs199473239'), ('SCN5A', 'rs199473240'), ('SCN5A', 'rs199473241'), ('SCN5A', 'rs199473242'), ('SCN5A', 'rs199473244'), ('SCN5A', 'rs199473245'), ('SCN5A', 'rs199473246'), ('SCN5A', 'rs199473247'), ('SCN5A', 'rs199473248'), ('SCN5A', 'rs199473249'), ('SCN5A', 'rs199473250'), ('SCN5A', 'rs199473251'), ('SCN5A', 'rs199473252'), ('SCN5A', 'rs199473254'), ('SCN5A', 'rs199473261'), ('SCN5A', 'rs199473266'), ('SCN5A', 'rs199473267'), ('SCN5A', 'rs199473269'), ('SCN5A', 'rs199473270'), ('SCN5A', 'rs199473271'), ('SCN5A', 'rs199473273'), ('SCN5A', 'rs199473274'), ('SCN5A', 'rs199473275'), ('SCN5A', 'rs199473280'), ('SCN5A', 'rs199473281'), ('SCN5A', 'rs199473282'), ('SCN5A', 'rs199473287'), ('SCN5A', 'rs199473289'), ('SCN5A', 'rs199473292'), ('SCN5A', 'rs199473293'), ('SCN5A', 'rs199473294'), ('SCN5A', 'rs199473295'), ('SCN5A', 'rs199473297'), ('SCN5A', 'rs199473298'), ('SCN5A', 'rs199473299'), ('SCN5A', 'rs199473302'), ('SCN5A', 'rs199473304'), ('SCN5A', 'rs199473305'), ('SCN5A', 'rs199473309'), ('SCN5A', 'rs199473311'), ('SCN5A', 'rs199473315'), ('SCN5A', 'rs199473316'), ('SCN5A', 'rs199473318'), ('SCN5A', 'rs199473320'), ('SCN5A', 'rs199473322'), ('SCN5A', 'rs199473323'), ('SCN5A', 'rs199473329'), ('SCN5A', 'rs199473554'), ('SCN5A', 'rs199473556'), ('SCN5A', 'rs199473557'), ('SCN5A', 'rs199473558'), ('SCN5A', 'rs199473559'), ('SCN5A', 'rs199473560'), ('SCN5A', 'rs199473561'), ('SCN5A', 'rs199473562'), ('SCN5A', 'rs199473564'), ('SCN5A', 'rs199473565'), ('SCN5A', 'rs199473566'), ('SCN5A', 'rs199473567'), ('SCN5A', 'rs199473568'), ('SCN5A', 'rs199473570'), ('SCN5A', 'rs199473573'), ('SCN5A', 'rs199473574'), ('SCN5A', 'rs199473577'), ('SCN5A', 'rs199473582'), ('SCN5A', 'rs199473584'), ('SCN5A', 'rs199473586'), ('SCN5A', 'rs199473587'), ('SCN5A', 'rs199473588'), ('SCN5A', 'rs199473589'), ('SCN5A', 'rs199473592'), ('SCN5A', 'rs199473593'), ('SCN5A', 'rs199473597'), ('SCN5A', 'rs199473599'), ('SCN5A', 'rs199473601'), ('SCN5A', 'rs199473605'), ('SCN5A', 'rs199473608'), ('SCN5A', 'rs199473609'), ('SCN5A', 'rs199473610'), ('SCN5A', 'rs199473611'), ('SCN5A', 'rs199473612'), ('SCN5A', 'rs199473613'), ('SCN5A', 'rs199473614'), ('SCN5A', 'rs199473617'), ('SCN5A', 'rs199473620'), ('SCN5A', 'rs199473621'), ('SCN5A', 'rs199473623'), ('SCN5A', 'rs199473624'), ('SCN5A', 'rs199473625'), ('SCN5A', 'rs199473626'), ('SCN5A', 'rs199473628'), ('SCN5A', 'rs199473629'), ('SCN5A', 'rs199473634'), ('SCN5A', 'rs199473636'), ('SCN5A', 'rs199473637'), ('SCN5A', 'rs199473639'), ('SCN5A', 'rs28937316'), ('SCN5A', 'rs28937318'), ('SCN5A', 'rs35310524'), ('SCN5A', 'rs370438420'), ('SCN5A', 'rs3918389'), ('SCN5A', 'rs397514251'), ('SCN5A', 'rs41261344'), ('SCN5A', 'rs41311087'), ('SCN5A', 'rs41311117'), ('SCN5A', 'rs41311127'), ('SCN5A', 'rs41315493'), ('SCN5A', 'rs45471994'), ('SCN5A', 'rs45514691'), ('SCN5A', 'rs45546039'), ('SCN5A', 'rs45609733'), ('SCN5A', 'rs45620037'), ('SCN5A', 'rs45627438'), ('SCN5A', 'rs483353016'), ('SCN5A', 'rs72549410'), ('SCN5A', 'rs727503411'), ('SCN5A', 'rs727504801'), ('SCN5A', 'rs727505158'), ('SCN5A', 'rs747643709'), ('SCN5A', 'rs748312802'), ('SCN5A', 'rs749697698'), ('SCN5A', 'rs756159737'), ('SCN5A', 'rs759235726'), ('SCN5A', 'rs759924541'), ('SCN5A', 'rs769349991'), ('SCN5A', 'rs775234338'), ('SCN5A', 'rs775538425'), ('SCN5A', 'rs777689378'), ('SCN5A', 'rs786204839'), ('SCN5A', 'rs79299226'), ('SCN5A', 'rs794728843'), ('SCN5A', 'rs794728846'), ('SCN5A', 'rs794728849'), ('SCN5A', 'rs794728865'), ('SCN5A', 'rs794728879'), ('SCN5A', 'rs794728906'), ('SCN5A', 'rs794728911'), ('SCN5A', 'rs794728912'), ('SCN5A', 'rs794728914'), ('SCN5A', 'rs794728924'), ('SCN5A', 'rs794728931'), ('SCN5A', 'rs863224532'), ('SCN5A', 'rs863224533'), ('SCN5A', 'rs863225273'), ('SCN5A', 'rs864622270'), ('SCN5A', 'rs869025520'), ('SCN5A', 'rs869025522'), ('SCN5A', 'rs878855287'), ('SCN5A', 'rs886037904'), ('VCL', 'rs774870551')]
0 variants in opentargets and not in clinvar: []
1217 variants in clinvar and not in opentargets: [('ANK2', 'rs148405740'), ('ANK2', 'rs730880049'), ('ANKRD1', 'rs869025363'), ('CACNA1C', 'rs1057518456'), ('CACNA1C', 'rs111442547'), ('CACNA1C', 'rs111606207'), ('CACNA1C', 'rs112170830'), ('CACNA1C', 'rs121912775'), ('CACNA1C', 'rs121912776'), ('CACNA1C', 'rs12828687'), ('CACNA1C', 'rs142476147'), ('CACNA1C', 'rs186015395'), ('CACNA1C', 'rs186708407'), ('CACNA1C', 'rs186741807'), ('CACNA1C', 'rs199473391'), ('CACNA1C', 'rs199473392'), ('CACNA1C', 'rs199473660'), ('CACNA1C', 'rs199538058'), ('CACNA1C', 'rs199694744'), ('CACNA1C', 'rs200231105'), ('CACNA1C', 'rs200588235'), ('CACNA1C', 'rs201258230'), ('CACNA1C', 'rs201492706'), ('CACNA1C', 'rs201756421'), ('CACNA1C', 'rs367895193'), ('CACNA1C', 'rs369267978'), ('CACNA1C', 'rs369438564'), ('CACNA1C', 'rs369673473'), ('CACNA1C', 'rs370145265'), ('CACNA1C', 'rs370630496'), ('CACNA1C', 'rs374857905'), ('CACNA1C', 'rs375818733'), ('CACNA1C', 'rs376987352'), ('CACNA1C', 'rs377165829'), ('CACNA1C', 'rs533634115'), ('CACNA1C', 'rs545511851'), ('CACNA1C', 'rs547615657'), ('CACNA1C', 'rs555721726'), ('CACNA1C', 'rs561365937'), ('CACNA1C', 'rs563090568'), ('CACNA1C', 'rs56394008'), ('CACNA1C', 'rs567401056'), ('CACNA1C', 'rs748926089'), ('CACNA1C', 'rs749753216'), ('CACNA1C', 'rs751166285'), ('CACNA1C', 'rs752000790'), ('CACNA1C', 'rs752736296'), ('CACNA1C', 'rs753892795'), ('CACNA1C', 'rs755167125'), ('CACNA1C', 'rs755579963'), ('CACNA1C', 'rs756364065'), ('CACNA1C', 'rs757966245'), ('CACNA1C', 'rs758461435'), ('CACNA1C', 'rs760888275'), ('CACNA1C', 'rs762376206'), ('CACNA1C', 'rs763622598'), ('CACNA1C', 'rs764323907'), ('CACNA1C', 'rs767190987'), ('CACNA1C', 'rs768270021'), ('CACNA1C', 'rs768830617'), ('CACNA1C', 'rs773930851'), ('CACNA1C', 'rs774165526'), ('CACNA1C', 'rs774490908'), ('CACNA1C', 'rs775331521'), ('CACNA1C', 'rs776522592'), ('CACNA1C', 'rs778220127'), ('CACNA1C', 'rs779009338'), ('CACNA1C', 'rs779194497'), ('CACNA1C', 'rs781395450'), ('CACNA1C', 'rs886038918'), ('CACNA1C', 'rs886039214'), ('CACNA1C', 'rs886049148'), ('CACNA1C', 'rs886049149'), ('CACNA1C', 'rs886049150'), ('CACNA1C', 'rs886049202'), ('CACNA1C', 'rs886049203'), ('CACNA1C', 'rs886049204'), ('CACNA1C', 'rs886049205'), ('CACNA1C', 'rs886049206'), ('CACNA1C', 'rs886049207'), ('CACNA1C', 'rs886049208'), ('CACNA1C', 'rs886049209'), ('CACNA1C', 'rs886049210'), ('CACNA1C', 'rs886049211'), ('CACNA1C', 'rs886049212'), ('CACNA1C', 'rs886049213'), ('CACNA1C', 'rs886049214'), ('CACNA1C', 'rs886049216'), ('CACNA1C', 'rs886049217'), ('CACNA1C', 'rs886049218'), ('CACNA1C', 'rs886049219'), ('CACNA1C', 'rs886049221'), ('CACNA1C', 'rs886049222'), ('CACNA1C', 'rs886049223'), ('CACNA1C', 'rs886049224'), ('CACNA1C', 'rs886049225'), ('CACNA1C', 'rs886049226'), ('CACNA1C', 'rs886049227'), ('CACNA1C', 'rs886049228'), ('CACNA1C', 'rs886049229'), ('CACNA1C', 'rs886049230'), ('CACNA1C', 'rs886049231'), ('CACNA1C', 'rs886049232'), ('CACNA1C', 'rs886049233'), ('CACNA1C', 'rs886049234'), ('CACNA1C', 'rs886049235'), ('CACNA1C', 'rs886049236'), ('CACNA1C', 'rs886049237'), ('CACNA1C', 'rs886049238'), ('CACNA1C', 'rs886049239'), ('CACNA1C', 'rs886049240'), ('CACNA1C', 'rs886049241'), ('CACNA1C', 'rs886049243'), ('CACNA1C', 'rs886049244'), ('CACNA1C', 'rs886049245'), ('CACNA1C', 'rs886049246'), ('CACNA1C', 'rs886049247'), ('CACNA1C', 'rs886049248'), ('CACNA1C', 'rs886049249'), ('CACNA1C', 'rs886049250'), ('CACNA1C', 'rs886049251'), ('CACNA1C-AS1', 'rs200231105'), ('CACNA2D1', 'rs1060503151'), ('CACNA2D1', 'rs1163800062'), ('CACNA2D1', 'rs1218449046'), ('CACNA2D1', 'rs139608070'), ('CACNA2D1', 'rs141238313'), ('CACNA2D1', 'rs1477267428'), ('CACNA2D1', 'rs1554327285'), ('CACNA2D1', 'rs1554333986'), ('CACNA2D1', 'rs1554345090'), ('CACNA2D1', 'rs1554349582'), ('CACNA2D1', 'rs1554398187'), ('CACNA2D1', 'rs1554560384'), ('CACNA2D1', 'rs192741898'), ('CACNA2D1', 'rs201682618'), ('CACNA2D1', 'rs202108848'), ('CACNA2D1', 'rs368512946'), ('CACNA2D1', 'rs745501384'), ('CACNA2D1', 'rs756765026'), ('CACNA2D1', 'rs757313687'), ('CACNA2D1', 'rs771243374'), ('CACNA2D1', 'rs773095610'), ('CACNA2D1', 'rs780901801'), ('CACNA2D1', 'rs869025369'), ('CACNB2', 'rs1064795457'), ('CACNB2', 'rs111250176'), ('CACNB2', 'rs137886839'), ('CACNB2', 'rs138423466'), ('CACNB2', 'rs143326262'), ('CACNB2', 'rs144182966'), ('CACNB2', 'rs144509796'), ('CACNB2', 'rs149253719'), ('CACNB2', 'rs149793143'), ('CACNB2', 'rs150280879'), ('CACNB2', 'rs150528041'), ('CACNB2', 'rs151199943'), ('CACNB2', 'rs1554843746'), ('CACNB2', 'rs182163363'), ('CACNB2', 'rs182634399'), ('CACNB2', 'rs187815725'), ('CACNB2', 'rs191106518'), ('CACNB2', 'rs192508010'), ('CACNB2', 'rs200654601'), ('CACNB2', 'rs202152674'), ('CACNB2', 'rs34551674'), ('CACNB2', 'rs367928065'), ('CACNB2', 'rs368719191'), ('CACNB2', 'rs373932682'), ('CACNB2', 'rs376222853'), ('CACNB2', 'rs528559406'), ('CACNB2', 'rs536419495'), ('CACNB2', 'rs543872505'), ('CACNB2', 'rs546669133'), ('CACNB2', 'rs547804393'), ('CACNB2', 'rs551293049'), ('CACNB2', 'rs562896922'), ('CACNB2', 'rs564275776'), ('CACNB2', 'rs564407056'), ('CACNB2', 'rs568890834'), ('CACNB2', 'rs568986179'), ('CACNB2', 'rs61733968'), ('CACNB2', 'rs745337273'), ('CACNB2', 'rs750396182'), ('CACNB2', 'rs752637408'), ('CACNB2', 'rs753335762'), ('CACNB2', 'rs758274878'), ('CACNB2', 'rs759258778'), ('CACNB2', 'rs764843384'), ('CACNB2', 'rs76956014'), ('CACNB2', 'rs773767571'), ('CACNB2', 'rs775466397'), ('CACNB2', 'rs775896337'), ('CACNB2', 'rs778295363'), ('CACNB2', 'rs780734976'), ('CACNB2', 'rs781283574'), ('CACNB2', 'rs78378025'), ('CACNB2', 'rs875989812'), ('CACNB2', 'rs886046883'), ('CACNB2', 'rs886046884'), ('CACNB2', 'rs886046885'), ('CACNB2', 'rs886046886'), ('CACNB2', 'rs886046887'), ('CACNB2', 'rs886046891'), ('CACNB2', 'rs886046892'), ('CACNB2', 'rs886046893'), ('CACNB2', 'rs886046894'), ('CACNB2', 'rs886046896'), ('CACNB2', 'rs886046897'), ('CACNB2', 'rs886046898'), ('CACNB2', 'rs886046899'), ('CACNB2', 'rs886046901'), ('CACNB2', 'rs886046902'), ('CACNB2', 'rs886046906'), ('CACNB2', 'rs886046907'), ('CACNB2', 'rs886046908'), ('COL5A1', 'rs1564417691'), ('GPD1L', 'rs112122950'), ('GPD1L', 'rs112185839'), ('GPD1L', 'rs113764055'), ('GPD1L', 'rs114349261'), ('GPD1L', 'rs115291555'), ('GPD1L', 'rs116281194'), ('GPD1L', 'rs1216770303'), ('GPD1L', 'rs1376727184'), ('GPD1L', 'rs139494055'), ('GPD1L', 'rs140250795'), ('GPD1L', 'rs143486835'), ('GPD1L', 'rs144925784'), ('GPD1L', 'rs148361833'), ('GPD1L', 'rs148464224'), ('GPD1L', 'rs149641866'), ('GPD1L', 'rs1553659648'), ('GPD1L', 'rs1553660781'), ('GPD1L', 'rs1559565644'), ('GPD1L', 'rs1559579249'), ('GPD1L', 'rs182826539'), ('GPD1L', 'rs186019566'), ('GPD1L', 'rs201799095'), ('GPD1L', 'rs373602669'), ('GPD1L', 'rs531920801'), ('GPD1L', 'rs537616228'), ('GPD1L', 'rs538672341'), ('GPD1L', 'rs546574502'), ('GPD1L', 'rs558257162'), ('GPD1L', 'rs566007803'), ('GPD1L', 'rs72546642'), ('GPD1L', 'rs72546651'), ('GPD1L', 'rs72552291'), ('GPD1L', 'rs72552292'), ('GPD1L', 'rs72552294'), ('GPD1L', 'rs72558074'), ('GPD1L', 'rs755306391'), ('GPD1L', 'rs757146653'), ('GPD1L', 'rs757614405'), ('GPD1L', 'rs757638347'), ('GPD1L', 'rs759080305'), ('GPD1L', 'rs772985306'), ('GPD1L', 'rs777110449'), ('GPD1L', 'rs786204216'), ('GPD1L', 'rs786205268'), ('GPD1L', 'rs878855004'), ('GPD1L', 'rs886058331'), ('GPD1L', 'rs886058332'), ('GPD1L', 'rs886058333'), ('GPD1L', 'rs886058334'), ('GPD1L', 'rs886058335'), ('GPD1L', 'rs886058336'), ('GPD1L', 'rs886058337'), ('GPD1L', 'rs886058338'), ('HCN4', 'rs560874115'), ('HCN4', 'rs764493888'), ('KCND3', 'rs869025444'), ('KCNE1', 'rs74315445'), ('KCNE3', 'rs113583236'), ('KCNE3', 'rs121908441'), ('KCNE3', 'rs150406522'), ('KCNE3', 'rs182905404'), ('KCNE3', 'rs187700411'), ('KCNE3', 'rs191005723'), ('KCNE3', 'rs201843136'), ('KCNE3', 'rs41258394'), ('KCNE3', 'rs41315539'), ('KCNE3', 'rs41315541'), ('KCNE3', 'rs528760350'), ('KCNE3', 'rs529326016'), ('KCNE3', 'rs535500151'), ('KCNE3', 'rs540669024'), ('KCNE3', 'rs546242304'), ('KCNE3', 'rs549819195'), ('KCNE3', 'rs555082306'), ('KCNE3', 'rs566273812'), ('KCNE3', 'rs569357069'), ('KCNE3', 'rs570472222'), ('KCNE3', 'rs60016728'), ('KCNE3', 'rs72552105'), ('KCNE3', 'rs745623708'), ('KCNE3', 'rs753304260'), ('KCNE3', 'rs758082514'), ('KCNE3', 'rs764717543'), ('KCNE3', 'rs867623173'), ('KCNE3', 'rs886048645'), ('KCNE3', 'rs886048646'), ('KCNE3', 'rs886048647'), ('KCNE3', 'rs886048648'), ('KCNE3', 'rs886048650'), ('KCNE3', 'rs886048651'), ('KCNE3', 'rs886048652'), ('KCNE3', 'rs886048653'), ('KCNE3', 'rs886048654'), ('KCNE5', 'rs1420621771'), ('KCNE5', 'rs375008004'), ('KCNE5', 'rs764993726'), ('KCNH2', 'rs12720441'), ('KCNJ8', 'rs117808169'), ('KCNJ8', 'rs149127157'), ('KCNJ8', 'rs1555172510'), ('KCNJ8', 'rs1565662161'), ('KCNJ8', 'rs730880120'), ('KCNQ1', 'rs775608046'), ('MYBPC3', 'rs397515985'), ('PKP2', 'rs146882581'), ('PKP2', 'rs149930872'), ('SCN10A', 'rs1060501715'), ('SCN10A', 'rs1060501716'), ('SCN10A', 'rs1060501717'), ('SCN10A', 'rs1167279918'), ('SCN10A', 'rs1173154320'), ('SCN10A', 'rs1199205585'), ('SCN10A', 'rs1226072923'), ('SCN10A', 'rs1265687114'), ('SCN10A', 'rs1334180362'), ('SCN10A', 'rs1334461772'), ('SCN10A', 'rs1372622252'), ('SCN10A', 'rs1373914068'), ('SCN10A', 'rs138404783'), ('SCN10A', 'rs138832868'), ('SCN10A', 'rs139638446'), ('SCN10A', 'rs1397301108'), ('SCN10A', 'rs139861061'), ('SCN10A', 'rs140288103'), ('SCN10A', 'rs140825889'), ('SCN10A', 'rs141368548'), ('SCN10A', 'rs141810266'), ('SCN10A', 'rs142203439'), ('SCN10A', 'rs142235256'), ('SCN10A', 'rs142276689'), ('SCN10A', 'rs142884499'), ('SCN10A', 'rs143744796'), ('SCN10A', 'rs1450059546'), ('SCN10A', 'rs145032037'), ('SCN10A', 'rs145694222'), ('SCN10A', 'rs145712124'), ('SCN10A', 'rs146965005'), ('SCN10A', 'rs147844607'), ('SCN10A', 'rs148537653'), ('SCN10A', 'rs148663098'), ('SCN10A', 'rs149155352'), ('SCN10A', 'rs149504103'), ('SCN10A', 'rs150923753'), ('SCN10A', 'rs151303346'), ('SCN10A', 'rs1553612991'), ('SCN10A', 'rs1553613078'), ('SCN10A', 'rs1553614805'), ('SCN10A', 'rs1553616744'), ('SCN10A', 'rs1553619005'), ('SCN10A', 'rs1553623225'), ('SCN10A', 'rs1553625946'), ('SCN10A', 'rs1553626242'), ('SCN10A', 'rs1553626259'), ('SCN10A', 'rs1559407312'), ('SCN10A', 'rs1559409413'), ('SCN10A', 'rs1559414131'), ('SCN10A', 'rs1559414230'), ('SCN10A', 'rs1559415879'), ('SCN10A', 'rs1559419984'), ('SCN10A', 'rs1559424975'), ('SCN10A', 'rs192493052'), ('SCN10A', 'rs199503439'), ('SCN10A', 'rs199535863'), ('SCN10A', 'rs199715855'), ('SCN10A', 'rs199931920'), ('SCN10A', 'rs200645452'), ('SCN10A', 'rs200713724'), ('SCN10A', 'rs200714519'), ('SCN10A', 'rs201106879'), ('SCN10A', 'rs201342036'), ('SCN10A', 'rs201706560'), ('SCN10A', 'rs201955990'), ('SCN10A', 'rs202040659'), ('SCN10A', 'rs202174472'), ('SCN10A', 'rs202192818'), ('SCN10A', 'rs370880796'), ('SCN10A', 'rs371337228'), ('SCN10A', 'rs371803816'), ('SCN10A', 'rs371834340'), ('SCN10A', 'rs371909817'), ('SCN10A', 'rs372368062'), ('SCN10A', 'rs372907454'), ('SCN10A', 'rs373289770'), ('SCN10A', 'rs374341474'), ('SCN10A', 'rs374447261'), ('SCN10A', 'rs375926577'), ('SCN10A', 'rs375940680'), ('SCN10A', 'rs377492327'), ('SCN10A', 'rs539215014'), ('SCN10A', 'rs542554745'), ('SCN10A', 'rs553784643'), ('SCN10A', 'rs569261408'), ('SCN10A', 'rs746690639'), ('SCN10A', 'rs747044382'), ('SCN10A', 'rs747174454'), ('SCN10A', 'rs747296872'), ('SCN10A', 'rs747321219'), ('SCN10A', 'rs747486328'), ('SCN10A', 'rs747839312'), ('SCN10A', 'rs747848559'), ('SCN10A', 'rs748441157'), ('SCN10A', 'rs748854017'), ('SCN10A', 'rs750073618'), ('SCN10A', 'rs751252167'), ('SCN10A', 'rs752623537'), ('SCN10A', 'rs754130748'), ('SCN10A', 'rs755100226'), ('SCN10A', 'rs756133876'), ('SCN10A', 'rs756253735'), ('SCN10A', 'rs756547221'), ('SCN10A', 'rs757916036'), ('SCN10A', 'rs758157003'), ('SCN10A', 'rs759136534'), ('SCN10A', 'rs759842238'), ('SCN10A', 'rs762600386'), ('SCN10A', 'rs762798134'), ('SCN10A', 'rs764965507'), ('SCN10A', 'rs766017851'), ('SCN10A', 'rs766143752'), ('SCN10A', 'rs772484960'), ('SCN10A', 'rs774893568'), ('SCN10A', 'rs777258179'), ('SCN10A', 'rs779316495'), ('SCN10A', 'rs781354273'), ('SCN10A', 'rs910678839'), ('SCN1B', 'rs147073518'), ('SCN1B', 'rs72552027'), ('SCN1B', 'rs72558029'), ('SCN1B', 'rs886054339'), ('SCN1B', 'rs886054340'), ('SCN1B', 'rs886054341'), ('SCN3B', 'rs111341342'), ('SCN3B', 'rs114709124'), ('SCN3B', 'rs116885934'), ('SCN3B', 'rs117409744'), ('SCN3B', 'rs121918282'), ('SCN3B', 'rs138774330'), ('SCN3B', 'rs139934383'), ('SCN3B', 'rs144520035'), ('SCN3B', 'rs148244106'), ('SCN3B', 'rs184556043'), ('SCN3B', 'rs187400761'), ('SCN3B', 'rs370826688'), ('SCN3B', 'rs543489443'), ('SCN3B', 'rs544984224'), ('SCN3B', 'rs547303769'), ('SCN3B', 'rs553042856'), ('SCN3B', 'rs555303241'), ('SCN3B', 'rs558085329'), ('SCN3B', 'rs577244366'), ('SCN3B', 'rs72552139'), ('SCN3B', 'rs72552158'), ('SCN3B', 'rs72552164'), ('SCN3B', 'rs72552185'), ('SCN3B', 'rs72552191'), ('SCN3B', 'rs72552193'), ('SCN3B', 'rs72552194'), ('SCN3B', 'rs72552195'), ('SCN3B', 'rs72553906'), ('SCN3B', 'rs72553907'), ('SCN3B', 'rs72553909'), ('SCN3B', 'rs748097809'), ('SCN3B', 'rs751005040'), ('SCN3B', 'rs753258598'), ('SCN3B', 'rs758175811'), ('SCN3B', 'rs75996884'), ('SCN3B', 'rs76257004'), ('SCN3B', 'rs765294617'), ('SCN3B', 'rs77584352'), ('SCN3B', 'rs776449566'), ('SCN3B', 'rs80017720'), ('SCN3B', 'rs867302682'), ('SCN3B', 'rs886047884'), ('SCN3B', 'rs886047885'), ('SCN3B', 'rs886047886'), ('SCN3B', 'rs886047887'), ('SCN3B', 'rs886047888'), ('SCN3B', 'rs886047889'), ('SCN3B', 'rs886047890'), ('SCN3B', 'rs886047891'), ('SCN3B', 'rs886047892'), ('SCN3B', 'rs886047893'), ('SCN3B', 'rs886047894'), ('SCN3B', 'rs886047895'), ('SCN3B', 'rs886047897'), ('SCN3B', 'rs886047898'), ('SCN3B', 'rs886047899'), ('SCN3B', 'rs886047900'), ('SCN3B', 'rs886047901'), ('SCN3B', 'rs886047902'), ('SCN3B', 'rs886047903'), ('SCN3B', 'rs886047904'), ('SCN3B', 'rs886047905'), ('SCN3B', 'rs886047906'), ('SCN3B', 'rs886047907'), ('SCN5A', 'rs1011460663'), ('SCN5A', 'rs1038605800'), ('SCN5A', 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'rs794728906'), ('SCN5A', 'rs794728910'), ('SCN5A', 'rs794728911'), ('SCN5A', 'rs794728912'), ('SCN5A', 'rs794728914'), ('SCN5A', 'rs794728916'), ('SCN5A', 'rs794728924'), ('SCN5A', 'rs794728925'), ('SCN5A', 'rs794728927'), ('SCN5A', 'rs794728934'), ('SCN5A', 'rs794728935'), ('SCN5A', 'rs794728940'), ('SCN5A', 'rs863224532'), ('SCN5A', 'rs863224533'), ('SCN5A', 'rs863224816'), ('SCN5A', 'rs863225273'), ('SCN5A', 'rs864622270'), ('SCN5A', 'rs864622440'), ('SCN5A', 'rs865884072'), ('SCN5A', 'rs869025517'), ('SCN5A', 'rs869025520'), ('SCN5A', 'rs869025522'), ('SCN5A', 'rs878855287'), ('SCN5A', 'rs878855288'), ('SCN5A', 'rs878855289'), ('SCN5A', 'rs878855292'), ('SCN5A', 'rs878855294'), ('SCN5A', 'rs878855295'), ('SCN5A', 'rs878855296'), ('SCN5A', 'rs878911306'), ('SCN5A', 'rs879035421'), ('SCN5A', 'rs879255356'), ('SCN5A', 'rs886037904'), ('SCN5A', 'rs886058437'), ('SCN5A', 'rs886058438'), ('SCN5A', 'rs886058439'), ('SCN5A', 'rs886058440'), ('SCN5A', 'rs886058441'), ('SCN5A', 'rs886058442'), ('SCN5A', 'rs886058443'), ('SCN5A', 'rs886058444'), ('SCN5A', 'rs886058445'), ('SCN5A', 'rs886058446'), ('SCN5A', 'rs886058447'), ('SCN5A', 'rs886058448'), ('SCN5A', 'rs886058449'), ('SCN5A', 'rs886058450'), ('SCN5A', 'rs886058451'), ('SCN5A', 'rs886058452'), ('SCN5A', 'rs886058453'), ('SCN5A', 'rs886058454'), ('SCN5A', 'rs886058455'), ('SCN5A', 'rs886058456'), ('SCN5A', 'rs886058457'), ('SCN5A', 'rs886058458'), ('SCN5A', 'rs886058459'), ('SCN5A', 'rs886058460'), ('SCN5A', 'rs886058461'), ('SCN5A', 'rs886058462'), ('SCN5A', 'rs886058463'), ('SCN5A', 'rs886058464'), ('SCN5A', 'rs886058465'), ('SCN5A', 'rs886058466'), ('SCN5A', 'rs918933961'), ('SCN5A', 'rs949932623'), ('SCN5A', 'rs9858585'), ('SLMAP', 'rs1016820088'), ('SLMAP', 'rs1060503190'), ('SLMAP', 'rs140490085'), ('SLMAP', 'rs142516364'), ('SLMAP', 'rs142778041'), ('SLMAP', 'rs149548827'), ('SLMAP', 'rs150439110'), ('SLMAP', 'rs746146243'), ('SLMAP', 'rs750893840'), ('SLMAP', 'rs751083292'), ('SLMAP', 'rs754387957'), ('SLMAP', 'rs763740777'), ('SLMAP', 'rs901233405'), ('SNTA1', 'rs137986136'), ('TCAP', 'rs146906267'), ('TRPM4', 'rs172149856'), ('TRPM4', 'rs201907325'), ('TRPM4', 'rs201994425'), ('TRPM4', 'rs747192078'), ('TRPM4', 'rs878855029'), ('TTN', 'rs148067743'), ('TTN', 'rs368327166'), ('TTN', 'rs55980498'), ('TTN', 'rs72646873'), ('TTN', 'rs72648942'), ('TTN', 'rs72650031'), ('TTN', 'rs761362832'), ('TTR', 'rs745834030')]
957 variants in clinvar and not in disgenet: [('ANK2', 'rs148405740'), ('ANK2', 'rs730880049'), ('ANKRD1', 'rs869025363'), ('CACNA1C', 'rs1057518456'), ('CACNA1C', 'rs111442547'), ('CACNA1C', 'rs111606207'), ('CACNA1C', 'rs112170830'), ('CACNA1C', 'rs121912775'), ('CACNA1C', 'rs12828687'), ('CACNA1C', 'rs142476147'), ('CACNA1C', 'rs186015395'), ('CACNA1C', 'rs186708407'), ('CACNA1C', 'rs186741807'), ('CACNA1C', 'rs199473391'), ('CACNA1C', 'rs199473392'), ('CACNA1C', 'rs199473660'), ('CACNA1C', 'rs199538058'), ('CACNA1C', 'rs199694744'), ('CACNA1C', 'rs200231105'), ('CACNA1C', 'rs200588235'), ('CACNA1C', 'rs201258230'), ('CACNA1C', 'rs201492706'), ('CACNA1C', 'rs201756421'), ('CACNA1C', 'rs367895193'), ('CACNA1C', 'rs369267978'), ('CACNA1C', 'rs369438564'), ('CACNA1C', 'rs369673473'), ('CACNA1C', 'rs370145265'), ('CACNA1C', 'rs370630496'), ('CACNA1C', 'rs374857905'), ('CACNA1C', 'rs375818733'), ('CACNA1C', 'rs376987352'), ('CACNA1C', 'rs377165829'), ('CACNA1C', 'rs533634115'), ('CACNA1C', 'rs545511851'), ('CACNA1C', 'rs547615657'), ('CACNA1C', 'rs555721726'), ('CACNA1C', 'rs561365937'), ('CACNA1C', 'rs563090568'), ('CACNA1C', 'rs56394008'), ('CACNA1C', 'rs567401056'), ('CACNA1C', 'rs748926089'), ('CACNA1C', 'rs749753216'), ('CACNA1C', 'rs751166285'), ('CACNA1C', 'rs752000790'), ('CACNA1C', 'rs752736296'), ('CACNA1C', 'rs753892795'), ('CACNA1C', 'rs755167125'), ('CACNA1C', 'rs755579963'), ('CACNA1C', 'rs756364065'), ('CACNA1C', 'rs757966245'), ('CACNA1C', 'rs758461435'), ('CACNA1C', 'rs760888275'), ('CACNA1C', 'rs762376206'), ('CACNA1C', 'rs763622598'), ('CACNA1C', 'rs764323907'), ('CACNA1C', 'rs767190987'), ('CACNA1C', 'rs768270021'), ('CACNA1C', 'rs768830617'), ('CACNA1C', 'rs773930851'), ('CACNA1C', 'rs774165526'), ('CACNA1C', 'rs774490908'), ('CACNA1C', 'rs775331521'), ('CACNA1C', 'rs776522592'), ('CACNA1C', 'rs778220127'), ('CACNA1C', 'rs779009338'), ('CACNA1C', 'rs779194497'), ('CACNA1C', 'rs781395450'), ('CACNA1C', 'rs886038918'), ('CACNA1C', 'rs886039214'), ('CACNA1C', 'rs886049148'), ('CACNA1C', 'rs886049149'), ('CACNA1C', 'rs886049150'), ('CACNA1C', 'rs886049202'), ('CACNA1C', 'rs886049203'), ('CACNA1C', 'rs886049204'), ('CACNA1C', 'rs886049205'), ('CACNA1C', 'rs886049206'), ('CACNA1C', 'rs886049207'), ('CACNA1C', 'rs886049208'), ('CACNA1C', 'rs886049209'), ('CACNA1C', 'rs886049210'), ('CACNA1C', 'rs886049211'), ('CACNA1C', 'rs886049212'), ('CACNA1C', 'rs886049213'), ('CACNA1C', 'rs886049214'), ('CACNA1C', 'rs886049216'), ('CACNA1C', 'rs886049217'), ('CACNA1C', 'rs886049218'), ('CACNA1C', 'rs886049219'), ('CACNA1C', 'rs886049221'), ('CACNA1C', 'rs886049222'), ('CACNA1C', 'rs886049223'), ('CACNA1C', 'rs886049224'), ('CACNA1C', 'rs886049225'), ('CACNA1C', 'rs886049226'), ('CACNA1C', 'rs886049227'), ('CACNA1C', 'rs886049228'), ('CACNA1C', 'rs886049229'), ('CACNA1C', 'rs886049230'), ('CACNA1C', 'rs886049231'), ('CACNA1C', 'rs886049232'), ('CACNA1C', 'rs886049233'), ('CACNA1C', 'rs886049234'), ('CACNA1C', 'rs886049235'), ('CACNA1C', 'rs886049236'), ('CACNA1C', 'rs886049237'), ('CACNA1C', 'rs886049238'), ('CACNA1C', 'rs886049239'), ('CACNA1C', 'rs886049240'), ('CACNA1C', 'rs886049241'), ('CACNA1C', 'rs886049243'), ('CACNA1C', 'rs886049244'), ('CACNA1C', 'rs886049245'), ('CACNA1C', 'rs886049246'), ('CACNA1C', 'rs886049247'), ('CACNA1C', 'rs886049248'), ('CACNA1C', 'rs886049249'), ('CACNA1C', 'rs886049250'), ('CACNA1C', 'rs886049251'), ('CACNA1C-AS1', 'rs200231105'), ('CACNA2D1', 'rs1060503151'), ('CACNA2D1', 'rs1163800062'), ('CACNA2D1', 'rs1218449046'), ('CACNA2D1', 'rs139608070'), ('CACNA2D1', 'rs141238313'), ('CACNA2D1', 'rs1477267428'), ('CACNA2D1', 'rs1554327285'), ('CACNA2D1', 'rs1554333986'), ('CACNA2D1', 'rs1554345090'), ('CACNA2D1', 'rs1554349582'), ('CACNA2D1', 'rs1554398187'), ('CACNA2D1', 'rs1554560384'), ('CACNA2D1', 'rs192741898'), ('CACNA2D1', 'rs201682618'), ('CACNA2D1', 'rs202108848'), ('CACNA2D1', 'rs368512946'), ('CACNA2D1', 'rs745501384'), ('CACNA2D1', 'rs756765026'), ('CACNA2D1', 'rs757313687'), ('CACNA2D1', 'rs771243374'), ('CACNA2D1', 'rs773095610'), ('CACNA2D1', 'rs780901801'), ('CACNA2D1', 'rs869025369'), ('CACNB2', 'rs1064795457'), ('CACNB2', 'rs111250176'), ('CACNB2', 'rs137886839'), ('CACNB2', 'rs138423466'), ('CACNB2', 'rs143326262'), ('CACNB2', 'rs144182966'), ('CACNB2', 'rs144509796'), ('CACNB2', 'rs149253719'), ('CACNB2', 'rs149793143'), ('CACNB2', 'rs150280879'), ('CACNB2', 'rs150528041'), ('CACNB2', 'rs151199943'), ('CACNB2', 'rs1554843746'), ('CACNB2', 'rs182163363'), ('CACNB2', 'rs182634399'), ('CACNB2', 'rs187815725'), ('CACNB2', 'rs191106518'), ('CACNB2', 'rs192508010'), ('CACNB2', 'rs200654601'), ('CACNB2', 'rs202152674'), ('CACNB2', 'rs34551674'), ('CACNB2', 'rs367928065'), ('CACNB2', 'rs368719191'), ('CACNB2', 'rs373932682'), ('CACNB2', 'rs376222853'), ('CACNB2', 'rs528559406'), ('CACNB2', 'rs536419495'), ('CACNB2', 'rs543872505'), ('CACNB2', 'rs546669133'), ('CACNB2', 'rs547804393'), ('CACNB2', 'rs551293049'), ('CACNB2', 'rs562896922'), ('CACNB2', 'rs564275776'), ('CACNB2', 'rs564407056'), ('CACNB2', 'rs568890834'), ('CACNB2', 'rs568986179'), ('CACNB2', 'rs61733968'), ('CACNB2', 'rs745337273'), ('CACNB2', 'rs750396182'), ('CACNB2', 'rs752637408'), ('CACNB2', 'rs753335762'), ('CACNB2', 'rs758274878'), ('CACNB2', 'rs759258778'), ('CACNB2', 'rs764843384'), ('CACNB2', 'rs76956014'), ('CACNB2', 'rs773767571'), ('CACNB2', 'rs775466397'), ('CACNB2', 'rs775896337'), ('CACNB2', 'rs778295363'), ('CACNB2', 'rs780734976'), ('CACNB2', 'rs781283574'), ('CACNB2', 'rs78378025'), ('CACNB2', 'rs875989812'), ('CACNB2', 'rs886046883'), ('CACNB2', 'rs886046884'), ('CACNB2', 'rs886046885'), ('CACNB2', 'rs886046886'), ('CACNB2', 'rs886046887'), ('CACNB2', 'rs886046891'), ('CACNB2', 'rs886046892'), ('CACNB2', 'rs886046893'), ('CACNB2', 'rs886046894'), ('CACNB2', 'rs886046896'), ('CACNB2', 'rs886046897'), ('CACNB2', 'rs886046898'), ('CACNB2', 'rs886046899'), ('CACNB2', 'rs886046901'), ('CACNB2', 'rs886046902'), ('CACNB2', 'rs886046906'), ('CACNB2', 'rs886046907'), ('CACNB2', 'rs886046908'), ('COL5A1', 'rs1564417691'), ('GPD1L', 'rs112122950'), ('GPD1L', 'rs112185839'), ('GPD1L', 'rs113764055'), ('GPD1L', 'rs114349261'), ('GPD1L', 'rs115291555'), ('GPD1L', 'rs116281194'), ('GPD1L', 'rs1216770303'), ('GPD1L', 'rs1376727184'), ('GPD1L', 'rs139494055'), ('GPD1L', 'rs140250795'), ('GPD1L', 'rs143486835'), ('GPD1L', 'rs144925784'), ('GPD1L', 'rs148361833'), ('GPD1L', 'rs148464224'), ('GPD1L', 'rs149641866'), ('GPD1L', 'rs1553659648'), ('GPD1L', 'rs1553660781'), ('GPD1L', 'rs1559565644'), ('GPD1L', 'rs1559579249'), ('GPD1L', 'rs182826539'), ('GPD1L', 'rs186019566'), ('GPD1L', 'rs201799095'), ('GPD1L', 'rs373602669'), ('GPD1L', 'rs531920801'), ('GPD1L', 'rs537616228'), ('GPD1L', 'rs538672341'), ('GPD1L', 'rs546574502'), ('GPD1L', 'rs558257162'), ('GPD1L', 'rs566007803'), ('GPD1L', 'rs72546642'), ('GPD1L', 'rs72546651'), ('GPD1L', 'rs72552292'), ('GPD1L', 'rs72552294'), ('GPD1L', 'rs72558074'), ('GPD1L', 'rs755306391'), ('GPD1L', 'rs757146653'), ('GPD1L', 'rs757614405'), ('GPD1L', 'rs757638347'), ('GPD1L', 'rs759080305'), ('GPD1L', 'rs772985306'), ('GPD1L', 'rs777110449'), ('GPD1L', 'rs786204216'), ('GPD1L', 'rs786205268'), ('GPD1L', 'rs878855004'), ('GPD1L', 'rs886058331'), ('GPD1L', 'rs886058332'), ('GPD1L', 'rs886058333'), ('GPD1L', 'rs886058334'), ('GPD1L', 'rs886058335'), ('GPD1L', 'rs886058336'), ('GPD1L', 'rs886058337'), ('GPD1L', 'rs886058338'), ('HCN4', 'rs560874115'), ('HCN4', 'rs764493888'), ('KCND3', 'rs869025444'), ('KCNE1', 'rs74315445'), ('KCNE3', 'rs113583236'), ('KCNE3', 'rs121908441'), ('KCNE3', 'rs150406522'), ('KCNE3', 'rs182905404'), ('KCNE3', 'rs187700411'), ('KCNE3', 'rs191005723'), ('KCNE3', 'rs201843136'), ('KCNE3', 'rs41258394'), ('KCNE3', 'rs41315539'), ('KCNE3', 'rs41315541'), ('KCNE3', 'rs528760350'), ('KCNE3', 'rs529326016'), ('KCNE3', 'rs535500151'), ('KCNE3', 'rs540669024'), ('KCNE3', 'rs546242304'), ('KCNE3', 'rs549819195'), ('KCNE3', 'rs555082306'), ('KCNE3', 'rs566273812'), ('KCNE3', 'rs569357069'), ('KCNE3', 'rs570472222'), ('KCNE3', 'rs60016728'), ('KCNE3', 'rs72552105'), ('KCNE3', 'rs745623708'), ('KCNE3', 'rs753304260'), ('KCNE3', 'rs758082514'), ('KCNE3', 'rs764717543'), ('KCNE3', 'rs867623173'), ('KCNE3', 'rs886048645'), ('KCNE3', 'rs886048646'), ('KCNE3', 'rs886048647'), ('KCNE3', 'rs886048648'), ('KCNE3', 'rs886048650'), ('KCNE3', 'rs886048651'), ('KCNE3', 'rs886048652'), ('KCNE3', 'rs886048653'), ('KCNE3', 'rs886048654'), ('KCNE5', 'rs1420621771'), ('KCNE5', 'rs375008004'), ('KCNE5', 'rs764993726'), ('KCNJ8', 'rs117808169'), ('KCNJ8', 'rs149127157'), ('KCNJ8', 'rs1555172510'), ('KCNJ8', 'rs1565662161'), ('KCNJ8', 'rs730880120'), ('KCNQ1', 'rs775608046'), ('MYBPC3', 'rs397515985'), ('PKP2', 'rs146882581'), ('PKP2', 'rs149930872'), ('SCN10A', 'rs1060501715'), ('SCN10A', 'rs1060501716'), ('SCN10A', 'rs1060501717'), ('SCN10A', 'rs1167279918'), ('SCN10A', 'rs1173154320'), ('SCN10A', 'rs1199205585'), ('SCN10A', 'rs1226072923'), ('SCN10A', 'rs1265687114'), ('SCN10A', 'rs1334180362'), ('SCN10A', 'rs1334461772'), ('SCN10A', 'rs1372622252'), ('SCN10A', 'rs1373914068'), ('SCN10A', 'rs138404783'), ('SCN10A', 'rs138832868'), ('SCN10A', 'rs139638446'), ('SCN10A', 'rs1397301108'), ('SCN10A', 'rs139861061'), ('SCN10A', 'rs140288103'), ('SCN10A', 'rs140825889'), ('SCN10A', 'rs141368548'), ('SCN10A', 'rs141810266'), ('SCN10A', 'rs142203439'), ('SCN10A', 'rs142235256'), ('SCN10A', 'rs142276689'), ('SCN10A', 'rs142884499'), ('SCN10A', 'rs143744796'), ('SCN10A', 'rs1450059546'), ('SCN10A', 'rs145032037'), ('SCN10A', 'rs145694222'), ('SCN10A', 'rs145712124'), ('SCN10A', 'rs146965005'), ('SCN10A', 'rs147844607'), ('SCN10A', 'rs148537653'), ('SCN10A', 'rs148663098'), ('SCN10A', 'rs149155352'), ('SCN10A', 'rs149504103'), ('SCN10A', 'rs150923753'), ('SCN10A', 'rs151303346'), ('SCN10A', 'rs1553612991'), ('SCN10A', 'rs1553613078'), ('SCN10A', 'rs1553614805'), ('SCN10A', 'rs1553616744'), ('SCN10A', 'rs1553619005'), ('SCN10A', 'rs1553623225'), ('SCN10A', 'rs1553625946'), ('SCN10A', 'rs1553626242'), ('SCN10A', 'rs1553626259'), ('SCN10A', 'rs1559407312'), ('SCN10A', 'rs1559409413'), ('SCN10A', 'rs1559414131'), ('SCN10A', 'rs1559414230'), ('SCN10A', 'rs1559415879'), ('SCN10A', 'rs1559419984'), ('SCN10A', 'rs1559424975'), ('SCN10A', 'rs192493052'), ('SCN10A', 'rs199503439'), ('SCN10A', 'rs199535863'), ('SCN10A', 'rs199715855'), ('SCN10A', 'rs199931920'), ('SCN10A', 'rs200645452'), ('SCN10A', 'rs200713724'), ('SCN10A', 'rs200714519'), ('SCN10A', 'rs201106879'), ('SCN10A', 'rs201342036'), ('SCN10A', 'rs201706560'), ('SCN10A', 'rs201955990'), ('SCN10A', 'rs202040659'), ('SCN10A', 'rs202174472'), ('SCN10A', 'rs202192818'), ('SCN10A', 'rs370880796'), ('SCN10A', 'rs371337228'), ('SCN10A', 'rs371803816'), ('SCN10A', 'rs371834340'), ('SCN10A', 'rs371909817'), ('SCN10A', 'rs372368062'), ('SCN10A', 'rs372907454'), ('SCN10A', 'rs373289770'), ('SCN10A', 'rs374341474'), ('SCN10A', 'rs374447261'), ('SCN10A', 'rs375926577'), ('SCN10A', 'rs375940680'), ('SCN10A', 'rs377492327'), ('SCN10A', 'rs539215014'), ('SCN10A', 'rs542554745'), ('SCN10A', 'rs553784643'), ('SCN10A', 'rs569261408'), ('SCN10A', 'rs746690639'), ('SCN10A', 'rs747044382'), ('SCN10A', 'rs747174454'), ('SCN10A', 'rs747296872'), ('SCN10A', 'rs747321219'), ('SCN10A', 'rs747486328'), ('SCN10A', 'rs747839312'), ('SCN10A', 'rs747848559'), ('SCN10A', 'rs748441157'), ('SCN10A', 'rs748854017'), ('SCN10A', 'rs750073618'), ('SCN10A', 'rs751252167'), ('SCN10A', 'rs752623537'), ('SCN10A', 'rs754130748'), ('SCN10A', 'rs755100226'), ('SCN10A', 'rs756133876'), ('SCN10A', 'rs756253735'), ('SCN10A', 'rs756547221'), ('SCN10A', 'rs757916036'), ('SCN10A', 'rs758157003'), ('SCN10A', 'rs759136534'), ('SCN10A', 'rs759842238'), ('SCN10A', 'rs762600386'), ('SCN10A', 'rs762798134'), ('SCN10A', 'rs764965507'), ('SCN10A', 'rs766017851'), ('SCN10A', 'rs766143752'), ('SCN10A', 'rs772484960'), ('SCN10A', 'rs774893568'), ('SCN10A', 'rs777258179'), ('SCN10A', 'rs779316495'), ('SCN10A', 'rs781354273'), ('SCN10A', 'rs910678839'), ('SCN1B', 'rs147073518'), ('SCN1B', 'rs72552027'), ('SCN1B', 'rs72558029'), ('SCN1B', 'rs886054339'), ('SCN1B', 'rs886054340'), ('SCN1B', 'rs886054341'), ('SCN3B', 'rs111341342'), ('SCN3B', 'rs114709124'), ('SCN3B', 'rs116885934'), ('SCN3B', 'rs117409744'), ('SCN3B', 'rs138774330'), ('SCN3B', 'rs139934383'), ('SCN3B', 'rs144520035'), ('SCN3B', 'rs148244106'), ('SCN3B', 'rs184556043'), ('SCN3B', 'rs187400761'), ('SCN3B', 'rs370826688'), ('SCN3B', 'rs543489443'), ('SCN3B', 'rs544984224'), ('SCN3B', 'rs547303769'), ('SCN3B', 'rs553042856'), ('SCN3B', 'rs555303241'), ('SCN3B', 'rs558085329'), ('SCN3B', 'rs577244366'), ('SCN3B', 'rs72552139'), ('SCN3B', 'rs72552158'), ('SCN3B', 'rs72552164'), ('SCN3B', 'rs72552185'), ('SCN3B', 'rs72552191'), ('SCN3B', 'rs72552193'), ('SCN3B', 'rs72552194'), ('SCN3B', 'rs72552195'), ('SCN3B', 'rs72553906'), ('SCN3B', 'rs72553907'), ('SCN3B', 'rs72553909'), ('SCN3B', 'rs748097809'), ('SCN3B', 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('SCN5A', 'rs760016062'), ('SCN5A', 'rs760585484'), ('SCN5A', 'rs760837591'), ('SCN5A', 'rs761117662'), ('SCN5A', 'rs761369505'), ('SCN5A', 'rs761505485'), ('SCN5A', 'rs762012668'), ('SCN5A', 'rs762283891'), ('SCN5A', 'rs762818132'), ('SCN5A', 'rs762981322'), ('SCN5A', 'rs763550164'), ('SCN5A', 'rs763830252'), ('SCN5A', 'rs763880032'), ('SCN5A', 'rs763891399'), ('SCN5A', 'rs764252430'), ('SCN5A', 'rs764488677'), ('SCN5A', 'rs765907469'), ('SCN5A', 'rs767116750'), ('SCN5A', 'rs768246863'), ('SCN5A', 'rs768691853'), ('SCN5A', 'rs769473892'), ('SCN5A', 'rs770088052'), ('SCN5A', 'rs770390440'), ('SCN5A', 'rs771018427'), ('SCN5A', 'rs771243543'), ('SCN5A', 'rs772186966'), ('SCN5A', 'rs772258197'), ('SCN5A', 'rs772585696'), ('SCN5A', 'rs773016454'), ('SCN5A', 'rs773422233'), ('SCN5A', 'rs774432823'), ('SCN5A', 'rs774593360'), ('SCN5A', 'rs775485359'), ('SCN5A', 'rs776171341'), ('SCN5A', 'rs776705132'), ('SCN5A', 'rs776925980'), ('SCN5A', 'rs776980213'), ('SCN5A', 'rs777061524'), ('SCN5A', 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'rs140490085'), ('SLMAP', 'rs142516364'), ('SLMAP', 'rs142778041'), ('SLMAP', 'rs149548827'), ('SLMAP', 'rs150439110'), ('SLMAP', 'rs746146243'), ('SLMAP', 'rs750893840'), ('SLMAP', 'rs751083292'), ('SLMAP', 'rs754387957'), ('SLMAP', 'rs763740777'), ('SLMAP', 'rs901233405'), ('SNTA1', 'rs137986136'), ('TCAP', 'rs146906267'), ('TRPM4', 'rs172149856'), ('TRPM4', 'rs201907325'), ('TRPM4', 'rs201994425'), ('TRPM4', 'rs747192078'), ('TRPM4', 'rs878855029'), ('TTN', 'rs148067743'), ('TTN', 'rs368327166'), ('TTN', 'rs55980498'), ('TTN', 'rs72646873'), ('TTN', 'rs72648942'), ('TTN', 'rs72650031'), ('TTN', 'rs761362832'), ('TTR', 'rs745834030')]
30 variants in disgenet and not in clinvar: [('CACNA1C', 'rs765116077'), ('KCNH2', 'rs199473547'), ('KCNJ8', 'rs72554071'), ('NOS1AP', 'rs10494366'), ('RANGRF', 'rs751751942'), ('SCN10A', 'rs10428132'), ('SCN2B', 'rs587777023'), ('SCN3B', 'rs147205617'), ('SCN5A', 'rs11708996'), ('SCN5A', 'rs137854606'), ('SCN5A', 'rs1805124'), ('SCN5A', 'rs199473045'), ('SCN5A', 'rs199473160'), ('SCN5A', 'rs199473204'), ('SCN5A', 'rs199473246'), ('SCN5A', 'rs199473287'), ('SCN5A', 'rs199473293'), ('SCN5A', 'rs199473315'), ('SCN5A', 'rs199473318'), ('SCN5A', 'rs199473625'), ('SCN5A', 'rs35310524'), ('SCN5A', 'rs41261344'), ('SCN5A', 'rs41315493'), ('SCN5A', 'rs747643709'), ('SCN5A', 'rs769349991'), ('SCN5A', 'rs775234338'), ('SCN5A', 'rs775538425'), ('SCN5A', 'rs79299226'), ('SCN5A', 'rs794728931'), ('VCL', 'rs774870551')]
1217 variants in clinvar and not in opentargets: [('ANK2', 'rs148405740'), ('ANK2', 'rs730880049'), ('ANKRD1', 'rs869025363'), ('CACNA1C', 'rs1057518456'), ('CACNA1C', 'rs111442547'), ('CACNA1C', 'rs111606207'), ('CACNA1C', 'rs112170830'), ('CACNA1C', 'rs121912775'), ('CACNA1C', 'rs121912776'), ('CACNA1C', 'rs12828687'), ('CACNA1C', 'rs142476147'), ('CACNA1C', 'rs186015395'), ('CACNA1C', 'rs186708407'), ('CACNA1C', 'rs186741807'), ('CACNA1C', 'rs199473391'), ('CACNA1C', 'rs199473392'), ('CACNA1C', 'rs199473660'), ('CACNA1C', 'rs199538058'), ('CACNA1C', 'rs199694744'), ('CACNA1C', 'rs200231105'), ('CACNA1C', 'rs200588235'), ('CACNA1C', 'rs201258230'), ('CACNA1C', 'rs201492706'), ('CACNA1C', 'rs201756421'), ('CACNA1C', 'rs367895193'), ('CACNA1C', 'rs369267978'), ('CACNA1C', 'rs369438564'), ('CACNA1C', 'rs369673473'), ('CACNA1C', 'rs370145265'), ('CACNA1C', 'rs370630496'), ('CACNA1C', 'rs374857905'), ('CACNA1C', 'rs375818733'), ('CACNA1C', 'rs376987352'), ('CACNA1C', 'rs377165829'), ('CACNA1C', 'rs533634115'), ('CACNA1C', 'rs545511851'), ('CACNA1C', 'rs547615657'), ('CACNA1C', 'rs555721726'), ('CACNA1C', 'rs561365937'), ('CACNA1C', 'rs563090568'), ('CACNA1C', 'rs56394008'), ('CACNA1C', 'rs567401056'), ('CACNA1C', 'rs748926089'), ('CACNA1C', 'rs749753216'), ('CACNA1C', 'rs751166285'), ('CACNA1C', 'rs752000790'), ('CACNA1C', 'rs752736296'), ('CACNA1C', 'rs753892795'), ('CACNA1C', 'rs755167125'), ('CACNA1C', 'rs755579963'), ('CACNA1C', 'rs756364065'), ('CACNA1C', 'rs757966245'), ('CACNA1C', 'rs758461435'), ('CACNA1C', 'rs760888275'), ('CACNA1C', 'rs762376206'), ('CACNA1C', 'rs763622598'), ('CACNA1C', 'rs764323907'), ('CACNA1C', 'rs767190987'), ('CACNA1C', 'rs768270021'), ('CACNA1C', 'rs768830617'), ('CACNA1C', 'rs773930851'), ('CACNA1C', 'rs774165526'), ('CACNA1C', 'rs774490908'), ('CACNA1C', 'rs775331521'), ('CACNA1C', 'rs776522592'), ('CACNA1C', 'rs778220127'), ('CACNA1C', 'rs779009338'), ('CACNA1C', 'rs779194497'), ('CACNA1C', 'rs781395450'), ('CACNA1C', 'rs886038918'), ('CACNA1C', 'rs886039214'), ('CACNA1C', 'rs886049148'), ('CACNA1C', 'rs886049149'), ('CACNA1C', 'rs886049150'), ('CACNA1C', 'rs886049202'), ('CACNA1C', 'rs886049203'), ('CACNA1C', 'rs886049204'), ('CACNA1C', 'rs886049205'), ('CACNA1C', 'rs886049206'), ('CACNA1C', 'rs886049207'), ('CACNA1C', 'rs886049208'), ('CACNA1C', 'rs886049209'), ('CACNA1C', 'rs886049210'), ('CACNA1C', 'rs886049211'), ('CACNA1C', 'rs886049212'), ('CACNA1C', 'rs886049213'), ('CACNA1C', 'rs886049214'), ('CACNA1C', 'rs886049216'), ('CACNA1C', 'rs886049217'), ('CACNA1C', 'rs886049218'), ('CACNA1C', 'rs886049219'), ('CACNA1C', 'rs886049221'), ('CACNA1C', 'rs886049222'), ('CACNA1C', 'rs886049223'), ('CACNA1C', 'rs886049224'), ('CACNA1C', 'rs886049225'), ('CACNA1C', 'rs886049226'), ('CACNA1C', 'rs886049227'), ('CACNA1C', 'rs886049228'), ('CACNA1C', 'rs886049229'), ('CACNA1C', 'rs886049230'), ('CACNA1C', 'rs886049231'), ('CACNA1C', 'rs886049232'), ('CACNA1C', 'rs886049233'), ('CACNA1C', 'rs886049234'), ('CACNA1C', 'rs886049235'), ('CACNA1C', 'rs886049236'), ('CACNA1C', 'rs886049237'), ('CACNA1C', 'rs886049238'), ('CACNA1C', 'rs886049239'), ('CACNA1C', 'rs886049240'), ('CACNA1C', 'rs886049241'), ('CACNA1C', 'rs886049243'), ('CACNA1C', 'rs886049244'), ('CACNA1C', 'rs886049245'), ('CACNA1C', 'rs886049246'), ('CACNA1C', 'rs886049247'), ('CACNA1C', 'rs886049248'), ('CACNA1C', 'rs886049249'), ('CACNA1C', 'rs886049250'), ('CACNA1C', 'rs886049251'), ('CACNA1C-AS1', 'rs200231105'), ('CACNA2D1', 'rs1060503151'), ('CACNA2D1', 'rs1163800062'), ('CACNA2D1', 'rs1218449046'), ('CACNA2D1', 'rs139608070'), ('CACNA2D1', 'rs141238313'), ('CACNA2D1', 'rs1477267428'), ('CACNA2D1', 'rs1554327285'), ('CACNA2D1', 'rs1554333986'), ('CACNA2D1', 'rs1554345090'), ('CACNA2D1', 'rs1554349582'), ('CACNA2D1', 'rs1554398187'), ('CACNA2D1', 'rs1554560384'), ('CACNA2D1', 'rs192741898'), ('CACNA2D1', 'rs201682618'), ('CACNA2D1', 'rs202108848'), ('CACNA2D1', 'rs368512946'), ('CACNA2D1', 'rs745501384'), ('CACNA2D1', 'rs756765026'), ('CACNA2D1', 'rs757313687'), ('CACNA2D1', 'rs771243374'), ('CACNA2D1', 'rs773095610'), ('CACNA2D1', 'rs780901801'), ('CACNA2D1', 'rs869025369'), ('CACNB2', 'rs1064795457'), ('CACNB2', 'rs111250176'), ('CACNB2', 'rs137886839'), ('CACNB2', 'rs138423466'), ('CACNB2', 'rs143326262'), ('CACNB2', 'rs144182966'), ('CACNB2', 'rs144509796'), ('CACNB2', 'rs149253719'), ('CACNB2', 'rs149793143'), ('CACNB2', 'rs150280879'), ('CACNB2', 'rs150528041'), ('CACNB2', 'rs151199943'), ('CACNB2', 'rs1554843746'), ('CACNB2', 'rs182163363'), ('CACNB2', 'rs182634399'), ('CACNB2', 'rs187815725'), ('CACNB2', 'rs191106518'), ('CACNB2', 'rs192508010'), ('CACNB2', 'rs200654601'), ('CACNB2', 'rs202152674'), ('CACNB2', 'rs34551674'), ('CACNB2', 'rs367928065'), ('CACNB2', 'rs368719191'), ('CACNB2', 'rs373932682'), ('CACNB2', 'rs376222853'), ('CACNB2', 'rs528559406'), ('CACNB2', 'rs536419495'), ('CACNB2', 'rs543872505'), ('CACNB2', 'rs546669133'), ('CACNB2', 'rs547804393'), ('CACNB2', 'rs551293049'), ('CACNB2', 'rs562896922'), ('CACNB2', 'rs564275776'), ('CACNB2', 'rs564407056'), ('CACNB2', 'rs568890834'), ('CACNB2', 'rs568986179'), ('CACNB2', 'rs61733968'), ('CACNB2', 'rs745337273'), ('CACNB2', 'rs750396182'), ('CACNB2', 'rs752637408'), ('CACNB2', 'rs753335762'), ('CACNB2', 'rs758274878'), ('CACNB2', 'rs759258778'), ('CACNB2', 'rs764843384'), ('CACNB2', 'rs76956014'), ('CACNB2', 'rs773767571'), ('CACNB2', 'rs775466397'), ('CACNB2', 'rs775896337'), ('CACNB2', 'rs778295363'), ('CACNB2', 'rs780734976'), ('CACNB2', 'rs781283574'), ('CACNB2', 'rs78378025'), ('CACNB2', 'rs875989812'), ('CACNB2', 'rs886046883'), ('CACNB2', 'rs886046884'), ('CACNB2', 'rs886046885'), ('CACNB2', 'rs886046886'), ('CACNB2', 'rs886046887'), ('CACNB2', 'rs886046891'), ('CACNB2', 'rs886046892'), ('CACNB2', 'rs886046893'), ('CACNB2', 'rs886046894'), ('CACNB2', 'rs886046896'), ('CACNB2', 'rs886046897'), ('CACNB2', 'rs886046898'), ('CACNB2', 'rs886046899'), ('CACNB2', 'rs886046901'), ('CACNB2', 'rs886046902'), ('CACNB2', 'rs886046906'), ('CACNB2', 'rs886046907'), ('CACNB2', 'rs886046908'), ('COL5A1', 'rs1564417691'), ('GPD1L', 'rs112122950'), ('GPD1L', 'rs112185839'), ('GPD1L', 'rs113764055'), ('GPD1L', 'rs114349261'), ('GPD1L', 'rs115291555'), ('GPD1L', 'rs116281194'), ('GPD1L', 'rs1216770303'), ('GPD1L', 'rs1376727184'), ('GPD1L', 'rs139494055'), ('GPD1L', 'rs140250795'), ('GPD1L', 'rs143486835'), ('GPD1L', 'rs144925784'), ('GPD1L', 'rs148361833'), ('GPD1L', 'rs148464224'), ('GPD1L', 'rs149641866'), ('GPD1L', 'rs1553659648'), ('GPD1L', 'rs1553660781'), ('GPD1L', 'rs1559565644'), ('GPD1L', 'rs1559579249'), ('GPD1L', 'rs182826539'), ('GPD1L', 'rs186019566'), ('GPD1L', 'rs201799095'), ('GPD1L', 'rs373602669'), ('GPD1L', 'rs531920801'), ('GPD1L', 'rs537616228'), ('GPD1L', 'rs538672341'), ('GPD1L', 'rs546574502'), ('GPD1L', 'rs558257162'), ('GPD1L', 'rs566007803'), ('GPD1L', 'rs72546642'), ('GPD1L', 'rs72546651'), ('GPD1L', 'rs72552291'), ('GPD1L', 'rs72552292'), ('GPD1L', 'rs72552294'), ('GPD1L', 'rs72558074'), ('GPD1L', 'rs755306391'), ('GPD1L', 'rs757146653'), ('GPD1L', 'rs757614405'), ('GPD1L', 'rs757638347'), ('GPD1L', 'rs759080305'), ('GPD1L', 'rs772985306'), ('GPD1L', 'rs777110449'), ('GPD1L', 'rs786204216'), ('GPD1L', 'rs786205268'), ('GPD1L', 'rs878855004'), ('GPD1L', 'rs886058331'), ('GPD1L', 'rs886058332'), ('GPD1L', 'rs886058333'), ('GPD1L', 'rs886058334'), ('GPD1L', 'rs886058335'), ('GPD1L', 'rs886058336'), ('GPD1L', 'rs886058337'), ('GPD1L', 'rs886058338'), ('HCN4', 'rs560874115'), ('HCN4', 'rs764493888'), ('KCND3', 'rs869025444'), ('KCNE1', 'rs74315445'), ('KCNE3', 'rs113583236'), ('KCNE3', 'rs121908441'), ('KCNE3', 'rs150406522'), ('KCNE3', 'rs182905404'), ('KCNE3', 'rs187700411'), ('KCNE3', 'rs191005723'), ('KCNE3', 'rs201843136'), ('KCNE3', 'rs41258394'), ('KCNE3', 'rs41315539'), ('KCNE3', 'rs41315541'), ('KCNE3', 'rs528760350'), ('KCNE3', 'rs529326016'), ('KCNE3', 'rs535500151'), ('KCNE3', 'rs540669024'), ('KCNE3', 'rs546242304'), ('KCNE3', 'rs549819195'), ('KCNE3', 'rs555082306'), ('KCNE3', 'rs566273812'), ('KCNE3', 'rs569357069'), ('KCNE3', 'rs570472222'), ('KCNE3', 'rs60016728'), ('KCNE3', 'rs72552105'), ('KCNE3', 'rs745623708'), ('KCNE3', 'rs753304260'), ('KCNE3', 'rs758082514'), ('KCNE3', 'rs764717543'), ('KCNE3', 'rs867623173'), ('KCNE3', 'rs886048645'), ('KCNE3', 'rs886048646'), ('KCNE3', 'rs886048647'), ('KCNE3', 'rs886048648'), ('KCNE3', 'rs886048650'), ('KCNE3', 'rs886048651'), ('KCNE3', 'rs886048652'), ('KCNE3', 'rs886048653'), ('KCNE3', 'rs886048654'), ('KCNE5', 'rs1420621771'), ('KCNE5', 'rs375008004'), ('KCNE5', 'rs764993726'), ('KCNH2', 'rs12720441'), ('KCNJ8', 'rs117808169'), ('KCNJ8', 'rs149127157'), ('KCNJ8', 'rs1555172510'), ('KCNJ8', 'rs1565662161'), ('KCNJ8', 'rs730880120'), ('KCNQ1', 'rs775608046'), ('MYBPC3', 'rs397515985'), ('PKP2', 'rs146882581'), ('PKP2', 'rs149930872'), ('SCN10A', 'rs1060501715'), ('SCN10A', 'rs1060501716'), ('SCN10A', 'rs1060501717'), ('SCN10A', 'rs1167279918'), ('SCN10A', 'rs1173154320'), ('SCN10A', 'rs1199205585'), ('SCN10A', 'rs1226072923'), ('SCN10A', 'rs1265687114'), ('SCN10A', 'rs1334180362'), ('SCN10A', 'rs1334461772'), ('SCN10A', 'rs1372622252'), ('SCN10A', 'rs1373914068'), ('SCN10A', 'rs138404783'), ('SCN10A', 'rs138832868'), ('SCN10A', 'rs139638446'), ('SCN10A', 'rs1397301108'), ('SCN10A', 'rs139861061'), ('SCN10A', 'rs140288103'), ('SCN10A', 'rs140825889'), ('SCN10A', 'rs141368548'), ('SCN10A', 'rs141810266'), ('SCN10A', 'rs142203439'), ('SCN10A', 'rs142235256'), ('SCN10A', 'rs142276689'), ('SCN10A', 'rs142884499'), ('SCN10A', 'rs143744796'), ('SCN10A', 'rs1450059546'), ('SCN10A', 'rs145032037'), ('SCN10A', 'rs145694222'), ('SCN10A', 'rs145712124'), ('SCN10A', 'rs146965005'), ('SCN10A', 'rs147844607'), ('SCN10A', 'rs148537653'), ('SCN10A', 'rs148663098'), ('SCN10A', 'rs149155352'), ('SCN10A', 'rs149504103'), ('SCN10A', 'rs150923753'), ('SCN10A', 'rs151303346'), ('SCN10A', 'rs1553612991'), ('SCN10A', 'rs1553613078'), ('SCN10A', 'rs1553614805'), ('SCN10A', 'rs1553616744'), ('SCN10A', 'rs1553619005'), ('SCN10A', 'rs1553623225'), ('SCN10A', 'rs1553625946'), ('SCN10A', 'rs1553626242'), ('SCN10A', 'rs1553626259'), ('SCN10A', 'rs1559407312'), ('SCN10A', 'rs1559409413'), ('SCN10A', 'rs1559414131'), ('SCN10A', 'rs1559414230'), ('SCN10A', 'rs1559415879'), ('SCN10A', 'rs1559419984'), ('SCN10A', 'rs1559424975'), ('SCN10A', 'rs192493052'), ('SCN10A', 'rs199503439'), ('SCN10A', 'rs199535863'), ('SCN10A', 'rs199715855'), ('SCN10A', 'rs199931920'), ('SCN10A', 'rs200645452'), ('SCN10A', 'rs200713724'), ('SCN10A', 'rs200714519'), ('SCN10A', 'rs201106879'), ('SCN10A', 'rs201342036'), ('SCN10A', 'rs201706560'), ('SCN10A', 'rs201955990'), ('SCN10A', 'rs202040659'), ('SCN10A', 'rs202174472'), ('SCN10A', 'rs202192818'), ('SCN10A', 'rs370880796'), ('SCN10A', 'rs371337228'), ('SCN10A', 'rs371803816'), ('SCN10A', 'rs371834340'), ('SCN10A', 'rs371909817'), ('SCN10A', 'rs372368062'), ('SCN10A', 'rs372907454'), ('SCN10A', 'rs373289770'), ('SCN10A', 'rs374341474'), ('SCN10A', 'rs374447261'), ('SCN10A', 'rs375926577'), ('SCN10A', 'rs375940680'), ('SCN10A', 'rs377492327'), ('SCN10A', 'rs539215014'), ('SCN10A', 'rs542554745'), ('SCN10A', 'rs553784643'), ('SCN10A', 'rs569261408'), ('SCN10A', 'rs746690639'), ('SCN10A', 'rs747044382'), ('SCN10A', 'rs747174454'), ('SCN10A', 'rs747296872'), ('SCN10A', 'rs747321219'), ('SCN10A', 'rs747486328'), ('SCN10A', 'rs747839312'), ('SCN10A', 'rs747848559'), ('SCN10A', 'rs748441157'), ('SCN10A', 'rs748854017'), ('SCN10A', 'rs750073618'), ('SCN10A', 'rs751252167'), ('SCN10A', 'rs752623537'), ('SCN10A', 'rs754130748'), ('SCN10A', 'rs755100226'), ('SCN10A', 'rs756133876'), ('SCN10A', 'rs756253735'), ('SCN10A', 'rs756547221'), ('SCN10A', 'rs757916036'), ('SCN10A', 'rs758157003'), ('SCN10A', 'rs759136534'), ('SCN10A', 'rs759842238'), ('SCN10A', 'rs762600386'), ('SCN10A', 'rs762798134'), ('SCN10A', 'rs764965507'), ('SCN10A', 'rs766017851'), ('SCN10A', 'rs766143752'), ('SCN10A', 'rs772484960'), ('SCN10A', 'rs774893568'), ('SCN10A', 'rs777258179'), ('SCN10A', 'rs779316495'), ('SCN10A', 'rs781354273'), ('SCN10A', 'rs910678839'), ('SCN1B', 'rs147073518'), ('SCN1B', 'rs72552027'), ('SCN1B', 'rs72558029'), ('SCN1B', 'rs886054339'), ('SCN1B', 'rs886054340'), ('SCN1B', 'rs886054341'), ('SCN3B', 'rs111341342'), ('SCN3B', 'rs114709124'), ('SCN3B', 'rs116885934'), ('SCN3B', 'rs117409744'), ('SCN3B', 'rs121918282'), ('SCN3B', 'rs138774330'), ('SCN3B', 'rs139934383'), ('SCN3B', 'rs144520035'), ('SCN3B', 'rs148244106'), ('SCN3B', 'rs184556043'), ('SCN3B', 'rs187400761'), ('SCN3B', 'rs370826688'), ('SCN3B', 'rs543489443'), ('SCN3B', 'rs544984224'), ('SCN3B', 'rs547303769'), ('SCN3B', 'rs553042856'), ('SCN3B', 'rs555303241'), ('SCN3B', 'rs558085329'), ('SCN3B', 'rs577244366'), ('SCN3B', 'rs72552139'), ('SCN3B', 'rs72552158'), ('SCN3B', 'rs72552164'), ('SCN3B', 'rs72552185'), ('SCN3B', 'rs72552191'), ('SCN3B', 'rs72552193'), ('SCN3B', 'rs72552194'), ('SCN3B', 'rs72552195'), ('SCN3B', 'rs72553906'), ('SCN3B', 'rs72553907'), ('SCN3B', 'rs72553909'), ('SCN3B', 'rs748097809'), ('SCN3B', 'rs751005040'), ('SCN3B', 'rs753258598'), ('SCN3B', 'rs758175811'), ('SCN3B', 'rs75996884'), ('SCN3B', 'rs76257004'), ('SCN3B', 'rs765294617'), ('SCN3B', 'rs77584352'), ('SCN3B', 'rs776449566'), ('SCN3B', 'rs80017720'), ('SCN3B', 'rs867302682'), ('SCN3B', 'rs886047884'), ('SCN3B', 'rs886047885'), ('SCN3B', 'rs886047886'), ('SCN3B', 'rs886047887'), ('SCN3B', 'rs886047888'), ('SCN3B', 'rs886047889'), ('SCN3B', 'rs886047890'), ('SCN3B', 'rs886047891'), ('SCN3B', 'rs886047892'), ('SCN3B', 'rs886047893'), ('SCN3B', 'rs886047894'), ('SCN3B', 'rs886047895'), ('SCN3B', 'rs886047897'), ('SCN3B', 'rs886047898'), ('SCN3B', 'rs886047899'), ('SCN3B', 'rs886047900'), ('SCN3B', 'rs886047901'), ('SCN3B', 'rs886047902'), ('SCN3B', 'rs886047903'), ('SCN3B', 'rs886047904'), ('SCN3B', 'rs886047905'), ('SCN3B', 'rs886047906'), ('SCN3B', 'rs886047907'), ('SCN5A', 'rs1011460663'), ('SCN5A', 'rs1038605800'), ('SCN5A', 'rs1060499900'), ('SCN5A', 'rs1060501114'), ('SCN5A', 'rs1060501126'), ('SCN5A', 'rs1060501127'), ('SCN5A', 'rs1060501128'), ('SCN5A', 'rs1060501129'), ('SCN5A', 'rs1060501130'), ('SCN5A', 'rs1060501131'), ('SCN5A', 'rs1060501132'), ('SCN5A', 'rs1060501133'), ('SCN5A', 'rs1060501134'), ('SCN5A', 'rs1060501135'), ('SCN5A', 'rs1060501136'), ('SCN5A', 'rs1060501137'), ('SCN5A', 'rs1060501138'), ('SCN5A', 'rs1060501139'), ('SCN5A', 'rs1060501140'), ('SCN5A', 'rs1060501141'), ('SCN5A', 'rs1060501142'), ('SCN5A', 'rs1060501143'), ('SCN5A', 'rs1060501144'), ('SCN5A', 'rs1060501145'), ('SCN5A', 'rs1060501146'), ('SCN5A', 'rs1060501147'), ('SCN5A', 'rs1060501148'), ('SCN5A', 'rs1060501149'), ('SCN5A', 'rs1064792926'), ('SCN5A', 'rs1064795784'), ('SCN5A', 'rs1131691708'), ('SCN5A', 'rs114517792'), ('SCN5A', 'rs1184094156'), ('SCN5A', 'rs12720064'), ('SCN5A', 'rs12720452'), ('SCN5A', 'rs1276970820'), ('SCN5A', 'rs1278221673'), ('SCN5A', 'rs1314879329'), ('SCN5A', 'rs1318798411'), ('SCN5A', 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'rs560476223'), ('SCN5A', 'rs561475141'), ('SCN5A', 'rs561547165'), ('SCN5A', 'rs561922849'), ('SCN5A', 'rs566251672'), ('SCN5A', 'rs569249327'), ('SCN5A', 'rs569552176'), ('SCN5A', 'rs575883763'), ('SCN5A', 'rs587781157'), ('SCN5A', 'rs587781159'), ('SCN5A', 'rs61737825'), ('SCN5A', 'rs72549410'), ('SCN5A', 'rs72549411'), ('SCN5A', 'rs727503411'), ('SCN5A', 'rs727504495'), ('SCN5A', 'rs727504801'), ('SCN5A', 'rs727504822'), ('SCN5A', 'rs727505158'), ('SCN5A', 'rs730880207'), ('SCN5A', 'rs730880208'), ('SCN5A', 'rs730880211'), ('SCN5A', 'rs746291609'), ('SCN5A', 'rs746360906'), ('SCN5A', 'rs747251132'), ('SCN5A', 'rs748297358'), ('SCN5A', 'rs748312802'), ('SCN5A', 'rs749697698'), ('SCN5A', 'rs749769938'), ('SCN5A', 'rs751050999'), ('SCN5A', 'rs752824646'), ('SCN5A', 'rs753149586'), ('SCN5A', 'rs753835985'), ('SCN5A', 'rs755162776'), ('SCN5A', 'rs755194086'), ('SCN5A', 'rs755980331'), ('SCN5A', 'rs756159737'), ('SCN5A', 'rs756474485'), ('SCN5A', 'rs757119370'), ('SCN5A', 'rs757302500'), ('SCN5A', 'rs757532106'), ('SCN5A', 'rs758101066'), ('SCN5A', 'rs758282196'), ('SCN5A', 'rs758959053'), ('SCN5A', 'rs759036311'), ('SCN5A', 'rs759235726'), ('SCN5A', 'rs759584454'), ('SCN5A', 'rs75960619'), ('SCN5A', 'rs759924541'), ('SCN5A', 'rs760011764'), ('SCN5A', 'rs760016062'), ('SCN5A', 'rs760585484'), ('SCN5A', 'rs760837591'), ('SCN5A', 'rs761117662'), ('SCN5A', 'rs761369505'), ('SCN5A', 'rs761505485'), ('SCN5A', 'rs762012668'), ('SCN5A', 'rs762283891'), ('SCN5A', 'rs762818132'), ('SCN5A', 'rs762981322'), ('SCN5A', 'rs763550164'), ('SCN5A', 'rs763830252'), ('SCN5A', 'rs763880032'), ('SCN5A', 'rs763891399'), ('SCN5A', 'rs764252430'), ('SCN5A', 'rs764488677'), ('SCN5A', 'rs765907469'), ('SCN5A', 'rs767116750'), ('SCN5A', 'rs768246863'), ('SCN5A', 'rs768691853'), ('SCN5A', 'rs769473892'), ('SCN5A', 'rs770088052'), ('SCN5A', 'rs770390440'), ('SCN5A', 'rs771018427'), ('SCN5A', 'rs771243543'), ('SCN5A', 'rs772186966'), ('SCN5A', 'rs772258197'), ('SCN5A', 'rs772585696'), ('SCN5A', 'rs773016454'), ('SCN5A', 'rs773422233'), ('SCN5A', 'rs774432823'), ('SCN5A', 'rs774593360'), ('SCN5A', 'rs775485359'), ('SCN5A', 'rs776171341'), ('SCN5A', 'rs776705132'), ('SCN5A', 'rs776925980'), ('SCN5A', 'rs776980213'), ('SCN5A', 'rs777061524'), ('SCN5A', 'rs777689378'), ('SCN5A', 'rs778236407'), ('SCN5A', 'rs778522112'), ('SCN5A', 'rs779649600'), ('SCN5A', 'rs779669888'), ('SCN5A', 'rs779953279'), ('SCN5A', 'rs779999584'), ('SCN5A', 'rs780405533'), ('SCN5A', 'rs780761880'), ('SCN5A', 'rs781103369'), ('SCN5A', 'rs781104838'), ('SCN5A', 'rs781529391'), ('SCN5A', 'rs786204839'), ('SCN5A', 'rs786205271'), ('SCN5A', 'rs794728842'), ('SCN5A', 'rs794728843'), ('SCN5A', 'rs794728846'), ('SCN5A', 'rs794728849'), ('SCN5A', 'rs794728852'), ('SCN5A', 'rs794728853'), ('SCN5A', 'rs794728855'), ('SCN5A', 'rs794728865'), ('SCN5A', 'rs794728869'), ('SCN5A', 'rs794728875'), ('SCN5A', 'rs794728879'), ('SCN5A', 'rs794728883'), ('SCN5A', 'rs794728898'), ('SCN5A', 'rs794728899'), ('SCN5A', 'rs794728906'), ('SCN5A', 'rs794728910'), ('SCN5A', 'rs794728911'), ('SCN5A', 'rs794728912'), ('SCN5A', 'rs794728914'), ('SCN5A', 'rs794728916'), ('SCN5A', 'rs794728924'), ('SCN5A', 'rs794728925'), ('SCN5A', 'rs794728927'), ('SCN5A', 'rs794728934'), ('SCN5A', 'rs794728935'), ('SCN5A', 'rs794728940'), ('SCN5A', 'rs863224532'), ('SCN5A', 'rs863224533'), ('SCN5A', 'rs863224816'), ('SCN5A', 'rs863225273'), ('SCN5A', 'rs864622270'), ('SCN5A', 'rs864622440'), ('SCN5A', 'rs865884072'), ('SCN5A', 'rs869025517'), ('SCN5A', 'rs869025520'), ('SCN5A', 'rs869025522'), ('SCN5A', 'rs878855287'), ('SCN5A', 'rs878855288'), ('SCN5A', 'rs878855289'), ('SCN5A', 'rs878855292'), ('SCN5A', 'rs878855294'), ('SCN5A', 'rs878855295'), ('SCN5A', 'rs878855296'), ('SCN5A', 'rs878911306'), ('SCN5A', 'rs879035421'), ('SCN5A', 'rs879255356'), ('SCN5A', 'rs886037904'), ('SCN5A', 'rs886058437'), ('SCN5A', 'rs886058438'), ('SCN5A', 'rs886058439'), ('SCN5A', 'rs886058440'), ('SCN5A', 'rs886058441'), ('SCN5A', 'rs886058442'), ('SCN5A', 'rs886058443'), ('SCN5A', 'rs886058444'), ('SCN5A', 'rs886058445'), ('SCN5A', 'rs886058446'), ('SCN5A', 'rs886058447'), ('SCN5A', 'rs886058448'), ('SCN5A', 'rs886058449'), ('SCN5A', 'rs886058450'), ('SCN5A', 'rs886058451'), ('SCN5A', 'rs886058452'), ('SCN5A', 'rs886058453'), ('SCN5A', 'rs886058454'), ('SCN5A', 'rs886058455'), ('SCN5A', 'rs886058456'), ('SCN5A', 'rs886058457'), ('SCN5A', 'rs886058458'), ('SCN5A', 'rs886058459'), ('SCN5A', 'rs886058460'), ('SCN5A', 'rs886058461'), ('SCN5A', 'rs886058462'), ('SCN5A', 'rs886058463'), ('SCN5A', 'rs886058464'), ('SCN5A', 'rs886058465'), ('SCN5A', 'rs886058466'), ('SCN5A', 'rs918933961'), ('SCN5A', 'rs949932623'), ('SCN5A', 'rs9858585'), ('SLMAP', 'rs1016820088'), ('SLMAP', 'rs1060503190'), ('SLMAP', 'rs140490085'), ('SLMAP', 'rs142516364'), ('SLMAP', 'rs142778041'), ('SLMAP', 'rs149548827'), ('SLMAP', 'rs150439110'), ('SLMAP', 'rs746146243'), ('SLMAP', 'rs750893840'), ('SLMAP', 'rs751083292'), ('SLMAP', 'rs754387957'), ('SLMAP', 'rs763740777'), ('SLMAP', 'rs901233405'), ('SNTA1', 'rs137986136'), ('TCAP', 'rs146906267'), ('TRPM4', 'rs172149856'), ('TRPM4', 'rs201907325'), ('TRPM4', 'rs201994425'), ('TRPM4', 'rs747192078'), ('TRPM4', 'rs878855029'), ('TTN', 'rs148067743'), ('TTN', 'rs368327166'), ('TTN', 'rs55980498'), ('TTN', 'rs72646873'), ('TTN', 'rs72648942'), ('TTN', 'rs72650031'), ('TTN', 'rs761362832'), ('TTR', 'rs745834030')]
0 variants in opentargets and not in clinvar: []

-------------Merged data-------------
65 genes in total: HCN4,SCN1B,TTR,SCN3B,HARS,NCOA7,KCNE1,CALM3,CALM2,AKAP9,KCNK1,ANK2,MYH7,SCN5A,FGF12,PKP2,RANGRF,SNTA1,KCNQ1,SCN4A,NOS1AP,DSG2,DSP,SCN4B,FGF14,DLG1,KCNJ8,MYBPC3,CAV3,HGS,KCNA3,GPD1L,KCNE3,SRSF5,TBX5,KCND3,CACNA1C,ATN1,RYR2,FGF11,BHLHE40,NKX2-5,CACNA2D1,CALM1,COL5A1,KCND2,CACNB2,DMD,EPHA3,TTN,SCN10A,ABCC9,VCL,CACNA1C-AS1,SLMAP,SEMA3A,TCAP,HEY2,ANKRD1,GJA1,TRPM4,SCN2B,IDS,KCNH2,KCNE5
1246 variants in total: rs1559407312, rs774490908, rs41313667, rs199473220, rs1167279918, rs41313015, rs199473158, rs756765026, rs755579963, rs1553702937, rs397514251, rs199473248, rs1060501140, rs1553705586, rs886054341, rs886049240, rs886049207, rs886048653, rs754130748, rs1559734780, rs372907454, rs140490085, rs199473586, rs1559419984, rs199473100, rs201342036, rs786205268, rs546574502, rs886058444, rs794728865, rs172149856, rs879255356, rs886058437, rs45491996, rs745834030, rs781283574, rs112170830, rs730880049, rs199694744, rs878855295, rs949932623, rs199473565, rs755167125, rs869025517, rs777689378, rs199473070, rs886058451, rs1366120635, rs45627438, rs201706560, rs199473219, rs886049245, rs1553692699, rs75996884, rs746360906, rs757146653, rs374341474, rs142778041, rs886046891, rs3918389, rs370630496, rs1060501717, rs545511851, rs1278221673, rs199473124, rs199473628, rs886049246, rs777110449, rs368719191, rs199473079, rs886047888, rs564407056, rs137854614, rs199473558, rs28937318, rs764965507, rs768830617, rs199473086, rs886058465, rs763891399, rs1481582794, rs886047891, rs762600386, rs373932682, rs186942072, rs199473320, rs794728910, rs142276689, rs72552139, rs199473181, rs886058455, rs775538425, rs1038605800, rs199473160, rs201756421, rs137854608, rs186019566, rs863224532, rs1060501716, rs199473254, rs539215014, rs786204216, rs41315539, rs727504801, rs199473309, rs794728906, rs758082514, rs758959053, rs199473133, rs886039214, rs376222853, rs199473304, rs199473567, rs72552191, rs757966245, rs886058333, rs139934383, rs747044382, rs141810266, rs199473316, rs140825889, rs199473287, rs199473639, rs199473233, rs1553614805, rs1559725687, rs199473214, rs1060501135, rs199473143, rs137854612, rs1334461772, rs886047900, rs777258179, rs531920801, rs760016062, rs547615657, rs199473272, rs150280879, rs1060501134, rs202192818, rs201641342, rs776705132, rs752623537, rs112185839, rs1553623225, rs886046899, rs749753216, rs10428132, rs886054340, rs149127157, rs886049150, rs761362832, rs137854607, rs774870551, rs775485359, rs144520035, rs199473195, rs886049148, rs886047885, rs1559727734, rs886046908, rs886049208, rs764717543, rs199473185, rs1064795457, rs199473187, rs1163800062, rs150528041, rs1060501132, rs549819195, rs138774330, rs199473050, rs1064792926, rs1553692410, rs886058454, rs761505485, rs369058100, rs199473164, rs199473636, rs1559414230, rs367906630, rs886047899, rs60016728, rs1060501146, rs199473335, rs555303241, rs368678204, rs140288103, rs199473168, rs886058456, rs370880796, rs561922849, rs199473240, rs1060501133, rs199473211, rs397517951, rs185638763, rs45489199, rs148464224, rs886047895, rs886049224, rs199473280, rs199473156, rs368058564, rs199473178, rs199473054, rs111606207, rs143744796, rs45458203, rs199473066, rs562896922, rs878855292, rs114709124, rs886058443, rs187700411, rs199473144, rs137854615, rs117409744, rs1131691708, rs72552193, rs199473117, rs199473267, rs768691853, rs775331521, rs1473144775, rs756133876, rs72552294, rs199473310, rs569357069, rs886058466, rs199473607, rs794728916, rs748312802, rs886058457, rs113764055, rs528559406, rs199473250, rs199473288, rs12720441, rs199473208, rs759235726, rs151303346, rs1564417691, rs113583236, rs187370816, rs758157003, rs536201762, rs757119370, rs781529391, rs199473246, rs199473044, rs199473243, rs199473638, rs371308670, rs199473058, rs199473318, rs199473574, rs775234338, rs201682618, rs199473102, rs566273812, rs199473251, rs192508010, rs886047892, rs1559371879, rs773767571, rs199473598, rs1553607561, rs55980498, rs199473210, rs751005040, rs199473170, rs757313687, rs878855294, rs202152674, rs199473269, rs886049211, rs137854606, rs1060501128, rs794728931, rs1554333986, rs79299226, rs1559424975, rs543872505, rs878855288, rs558257162, rs551399685, rs886049236, rs199473641, rs1553699747, rs111341342, rs750396182, rs757638347, rs1559721808, rs199473147, rs199473252, rs1421700935, rs535500151, rs1554843746, rs1060501139, rs139638446, rs1276970820, rs121918282, rs72546642, rs199473605, rs199473571, rs886058337, rs762818132, rs150264233, rs1060503190, rs72549411, rs754387957, rs199473218, rs1553693632, rs886058334, rs199473556, rs772186966, rs886046901, rs137886839, rs199473207, rs199473547, rs199473629, rs543489443, rs77584352, rs199473063, rs886047887, rs1060501141, rs886047907, rs560476223, rs199473196, rs1060501137, rs886049222, rs886049221, rs45522138, rs199473620, rs759080305, rs1554560384, rs41315493, rs72552292, rs137854611, rs1060501126, rs199473125, rs727504495, rs199473153, rs199473330, rs61733968, rs199473067, rs139608070, rs199473230, rs886047901, rs727503411, rs41313703, rs886049225, rs199473570, rs199473110, rs72554071, rs199473194, rs184556043, rs1016820088, rs886058448, rs199473091, rs149793143, rs778522112, rs886048654, rs199473126, rs886058447, rs72558029, rs886049228, rs780734976, rs148405740, rs1559379802, rs1329499714, rs886049237, rs886049234, rs748926089, rs199473090, rs770390440, rs371313714, rs886049243, rs80017720, rs781354273, rs187815725, rs1559774986, rs774593360, rs373410109, rs747296872, rs369678002, rs199473083, rs199473584, rs755980331, rs886058439, rs199473129, rs1376727184, rs1565662161, rs575883763, rs199473392, rs369704754, rs187400761, rs1554398187, rs878855004, rs755162776, rs139861061, rs199473113, rs199503439, rs758175811, rs369673473, rs199473123, rs199473062, rs137854616, rs747192078, rs199473084, rs746690639, rs1553616744, rs1060499900, rs199473139, rs886058335, rs199473247, rs755194086, rs1060501127, rs369438564, rs730880120, rs150439110, rs199473624, rs141238313, rs568986179, rs199473311, rs886049239, rs886058458, rs555082306, rs757614405, rs145733679, rs199473245, rs886049206, rs1553704898, rs1314879329, rs148067743, rs1554345090, rs886047886, rs199473242, rs72650031, rs776980213, rs116281194, rs756547221, rs111250176, rs199473217, rs886049216, rs72552027, rs199473575, rs199473055, rs778220127, rs762283891, rs72648942, rs1060501149, rs199473234, rs886049244, rs41261344, rs886047894, rs886049226, rs1559757317, rs794728911, rs199473179, rs121912776, rs199473626, rs374314562, rs1553660781, rs199473621, rs61737825, rs1559721331, rs45475899, rs373156650, rs199473554, rs199473341, rs199473313, rs149504103, rs765907469, rs370114378, rs78378025, rs886047889, rs1372622252, rs187531872, rs770088052, rs779649600, rs199473602, rs1559757280, rs56394008, rs566251672, rs12828687, rs886058338, rs199473329, rs72553907, rs144509796, rs199473098, rs199473333, rs201258230, rs886047902, rs794728842, rs199473089, rs72552105, rs137854617, rs1559565644, rs748297358, rs149930872, rs886046886, rs1553619005, rs199473244, rs41313033, rs199473047, rs886049218, rs199473103, rs772585696, rs886046898, rs199473258, rs199473151, rs150923753, rs1060501131, rs587781159, rs747251132, rs143326262, rs775608046, rs199473097, rs76257004, rs368357262, rs1199205585, rs199473289, rs587781157, rs143486835, rs149253719, rs199473176, rs1373914068, rs886047884, rs863224816, rs117808169, rs367807565, rs41310769, rs886058460, rs886049212, rs36210420, rs748854017, rs140250795, rs869025522, rs528760350, rs201492706, rs886049217, rs886049227, rs759924541, rs199473145, rs794728879, rs199473559, rs561475141, rs1553702946, rs45546039, rs147205617, rs199473074, rs764843384, rs1559725364, rs886047904, rs201994425, rs763550164, rs142235256, rs1559409413, rs745623708, rs577244366, rs373602669, rs199473599, rs199473071, rs199473592, rs146965005, rs1060501148, rs764993726, rs794728925, rs148361833, rs199473606, rs886049241, rs371834340, rs566007803, rs886048647, rs199473293, rs1555172510, rs199473188, rs199473572, rs886047890, rs886049202, rs886058438, rs745337273, rs886049230, rs886048646, rs886046902, rs202114798, rs199473241, rs199473096, rs750893840, rs137986136, rs886049249, rs200034939, rs201276017, rs202174472, rs730880207, rs794728899, rs200645452, rs397514450, rs1060501142, rs201907325, rs538672341, rs148244106, rs794728898, rs185492581, rs886046887, rs553784643, rs1218449046, rs145694222, rs199473625, rs192493052, rs397517953, rs529326016, rs768270021, rs367895193, rs757916036, rs199473122, rs886046892, rs28937316, rs1060501138, rs199473552, rs147073518, rs199538058, rs773016454, rs397517956, rs763622598, rs375940680, rs773930851, rs753149586, rs368048551, rs756253735, rs561365937, rs546242304, rs137854604, rs370588133, rs41313687, rs373289770, rs45437099, rs758282196, rs199473582, rs12720452, rs794728924, rs199473577, rs865884072, rs199473623, rs1455337011, rs763740777, rs41313693, rs370438420, rs41312419, rs199473204, rs199473635, rs1265687114, rs752000790, rs763830252, rs766143752, rs199473315, rs886058462, rs1417036453, rs1553659648, rs199473275, rs199473045, rs141368548, rs199473270, rs1553695847, rs771243374, rs533634115, rs45553235, rs199473573, rs199473082, rs41310753, rs1559415879, rs199473146, rs779953279, rs886058446, rs199473339, rs757532106, rs199715855, rs527480102, rs886049204, rs41276525, rs762981322, rs551293049, rs182634399, rs794728934, rs202108848, rs199473157, rs149641866, rs772484960, rs763880032, rs144182966, rs776449566, rs199473590, rs540669024, rs199473562, rs199473610, rs11708996, rs886058464, rs752736296, rs199473159, rs199473088, rs886048648, rs199473578, rs1559778838, rs751751942, rs886049149, rs199473614, rs878855289, rs757302500, rs886058449, rs1373296470, rs137854601, rs199473564, rs199473174, rs886046885, rs781395450, rs139494055, rs1553695282, rs114517792, rs1554349582, rs567401056, rs1553704015, rs753892795, rs199473228, rs755100226, rs45459402, rs41311135, rs199473282, rs72546651, rs199473180, rs199473322, rs199473053, rs375306544, rs747839312, rs776925980, rs72552164, rs150406522, rs886048650, rs752637408, rs116885934, rs146882581, rs199473111, rs199473336, rs199473225, rs886058332, rs886058331, rs199473305, rs41311127, rs569249327, rs199473056, rs74315445, rs199473163, rs786204839, rs547804393, rs794728852, rs199473603, rs886054339, rs72549410, rs10494366, rs1322825102, rs771243543, rs199473048, rs730880211, rs869025369, rs1805124, rs1553626259, rs766017851, rs1553607617, rs765116077, rs199473609, rs886038918, rs570472222, rs200231105, rs199473118, rs753258598, rs199473141, rs886049203, rs199473069, rs199473550, rs199473637, rs142203439, rs148598985, rs749769938, rs1060503151, rs199473104, rs747486328, rs536419495, rs886047903, rs199473613, rs1559720961, rs199473237, rs730880208, rs1559579249, rs762012668, rs1553705529, rs794728875, rs886046907, rs794728843, rs759036311, rs41258394, rs864622270, rs114349261, rs886058440, rs199473660, rs200868190, rs760011764, rs560874115, rs776171341, rs199473236, rs138423466, rs199473073, rs774893568, rs1559720176, rs199473566, rs767190987, rs199473303, rs1559414131, rs1559720870, rs41311087, rs45609733, rs794728855, rs376965389, rs199473295, rs111442547, rs587777023, rs751166285, rs761369505, rs772258197, rs748441157, rs186741807, rs137854619, rs199473137, rs555721726, rs1060501715, rs148663098, rs142884499, rs149548827, rs368327166, rs886049205, rs199473186, rs886049229, rs199473167, rs864622440, rs45465995, rs199473205, rs200714519, rs771018427, rs1469078045, rs199473297, rs375614054, rs41315541, rs34551674, rs727504822, rs199473238, rs773095610, rs199473081, rs72552194, rs145032037, rs137854609, rs190416544, rs779999584, rs1060501114, rs1060501136, rs199473121, rs886046883, rs138832868, rs569261408, rs186708407, rs747321219, rs1471640168, rs199473292, rs762798134, rs878911306, rs371337228, rs886049232, rs72553909, rs201106879, rs772985306, rs199473092, rs752824646, rs377492327, rs199473112, rs769473892, rs201955990, rs41315489, rs869025444, rs794728846, rs199473568, rs779194497, rs199473266, rs148537653, rs794728935, rs1377226524, rs199473331, rs199473199, rs368512946, rs794728940, rs199473298, rs886049223, rs193922726, rs146906267, rs142516364, rs199473166, rs542554745, rs886047897, rs794728849, rs377165829, rs886058459, rs199473640, rs1553694258, rs199473182, rs199473072, rs200569112, rs564275776, rs1484635042, rs759136534, rs373118001, rs199473192, rs183988524, rs546849670, rs775466397, rs886046896, rs538707712, rs761117662, rs199473589, rs751083292, rs886047906, rs1060501145, rs199473052, rs886058463, rs1226072923, rs72552158, rs397515985, rs41311121, rs773422233, rs199473328, rs1559720461, rs1420621771, rs199473634, rs867302682, rs886046897, rs1554327285, rs9858585, rs768246863, rs1559738468, rs199473061, rs199473198, rs750073618, rs192379242, rs886058441, rs775896337, rs764323907, rs747174454, rs1064795784, rs370694515, rs199473263, rs886049233, rs886049248, rs1011460663, rs199473555, rs199473119, rs199473042, rs759258778, rs199473065, rs199473172, rs199473171, rs778295363, rs199473206, rs755306391, rs776522592, rs199473294, rs45502793, rs371909817, rs192741898, rs483353016, rs370346797, rs186015395, rs375323548, rs149155352, rs1060501147, rs778236407, rs886049210, rs1553612991, rs199473189, rs1553699663, rs886046893, rs794728869, rs875989812, rs569552176, rs886049247, rs1553700699, rs1490175548, rs72552185, rs901233405, rs375818733, rs886049250, rs553042856, rs869025363, rs199473265, rs35310524, rs746291609, rs749697698, rs199473175, rs199473302, rs886049231, rs199473284, rs1553696719, rs199473323, rs1216770303, rs199473561, rs199931920, rs546669133, rs751050999, rs199473601, rs199473281, rs878855029, rs748097809, rs886048645, rs199473600, rs199473224, rs371803816, rs199535863, rs199473093, rs191106518, rs1553693063, rs1553692734, rs1397301108, rs1057518456, rs137854602, rs886058442, rs918933961, rs375008004, rs756474485, rs199473608, rs727505158, rs1477267428, rs780405533, rs199473235, rs1060501129, rs760585484, rs45620037, rs199473177, rs1430691171, rs199473221, rs886058453, rs199473560, rs76956014, rs199473612, rs759584454, rs779009338, rs182050752, rs199473085, rs199473296, rs765294617, rs142476147, rs199473232, rs45503498, rs369565476, rs869025520, rs199473260, rs886047898, rs886049219, rs786205271, rs886049209, rs879035421, rs745501384, rs182826539, rs878855296, rs199473116, rs199473149, rs1318798411, rs886049238, rs72552291, rs794728914, rs147844607, rs886047905, rs1553704925, rs372368062, rs199473161, rs375926577, rs781103369, rs199473587, rs1553626242, rs199473325, rs376697724, rs199473286, rs137854600, rs758461435, rs756159737, rs1450059546, rs370145265, rs1334180362, rs200588235, rs1553625946, rs199473595, rs121912775, rs199473630, rs1559771615, rs753335762, rs886058461, rs72558074, rs199473229, rs41311117, rs779316495, rs199473128, rs199473391, rs764493888, rs544984224, rs780761880, rs767116750, rs878855287, rs72552195, rs369267978, rs561547165, rs910678839, rs199473154, rs199473597, rs760837591, rs201843136, rs121908441, rs758101066, rs774432823, rs199473593, rs1438675647, rs886048652, rs199473278, rs199473332, rs191840835, rs780901801, rs886046884, rs199473231, rs199473588, rs199473095, rs886048651, rs199473173, rs537616228, rs137854610, rs137854618, rs147795595, rs753304260, rs547303769, rs146848219, rs374447261, rs199473197, rs199473617, rs182163363, rs568890834, rs144925784, rs45514691, rs1464663200, rs199473314, rs1060501130, rs758274878, rs760888275, rs199473273, rs145712124, rs199473299, rs191009474, rs1559370502, rs137854603, rs794728912, rs1553692406, rs886049251, rs199473239, rs886046894, rs886058336, rs112122950, rs779669888, rs794728927, rs1559725648, rs886058450, rs886046906, rs41310765, rs45471994, rs138404783, rs886049213, rs199473209, rs1553699796, rs886058452, rs764488677, rs774165526, rs886037904, rs199473274, rs199473340, rs762376206, rs540984871, rs182905404, rs886049214, rs746146243, rs751252167, rs756364065, rs886058445, rs747848559, rs794728853, rs374857905, rs563090568, rs794728883, rs1173154320, rs781104838, rs1184094156, rs191005723, rs1060501143, rs1553695248, rs199473094, rs376987352, rs747643709, rs199473101, rs863224533, rs1553613078, rs753835985, rs769349991, rs115291555, rs199473261, rs72553906, rs200713724, rs199473051, rs199473076, rs199473557, rs1553692660, rs370826688, rs886049235, rs199473226, rs558085329, rs202040659, rs777061524, rs151199943, rs367928065, rs12720064, rs199473169, rs75960619, rs199473134, rs863225273, rs764252430, rs199473249, rs199473611, rs199473271, rs886047893, rs759842238, rs201799095, rs867623173, rs1060501144, rs199473213, rs45563942, rs72646873, rs200654601 
```
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## 2. Enrich gene list

The list of genes associated with given disease is then enriched by the script stored
stored in the `extend_network` directory.

#### **enrich_maps.R** Script for map and pathway enrichment

Should be run as `Rscript --vanilla enrich_maps.R <input_filename> <config_file>`

- `input_filename` should contain list of genes as HGNC symbols, one entry per line. Default is "input.txt" in the script folder.
- `config_file` contains the list of map instances and pathways to enrich. Default is "config.txt" in the script folder.

The script uses "config.txt" file, containing the list of minerva instances and 
pathways to query for enriched areas.

It provides output with the list of enriched map areas and pathways.

Statistical tests used for maps and pathways are different.

## 3. Filter variants by allele frequency
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#### Ensembl 
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The script [vepAllInOne.py](bh19-rare-diseases/associations/vepmining) retrives information about [allele frequencies](https://en.wikipedia.org/wiki/Allele\_frequency) in several populations available in the [Ensembl](http://www.ensembl.org/index.html) databse. This is done throug [this endpoint](https://rest.ensembl.org/documentation/info/vep\_id\_post) of the Ensembl API. 
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```commandline 
 python3 vepAllInOne.py -f <single column of rsid input file >   -t < float, allele frequency threshold below with variant is retained > 
```

It takes as *input* a file with a single column of rs# and give as *output* in the standard out a single column of rs#. 


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In the output there are the variants from the input that are either not described in the genomic databses contained in Ensembl or for which there is at least one population with allele frequency >= the threshold indicated in the command line. As an example, using a threshold of 0.10 will filter out form the input file all variants that have minor allele frequency eqaul to or greater than 10\%  in at least one population among those described in Ensembl. Also variant not present in Ensembl are filtered out under the assumption that they have never been described so far.

###### Comment on efficiency  
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## 3. Obtaining variant information

The script `minerva_variants.py` connects to [http://myvariant.info/](MyVariant.info) API and for each of the provided
variant identifiers (provided as a list of in the [dbSNP Reference numbers](dbSNP Reference SNP) ) gets genetic location
and also protein-level mapping. The protein-level mapping in MyVariant.info comes from the [dbNSFP database](https://sites.google.com/site/jpopgen/dbNSFP).

Usage:

```bash
python3 minerva_variants.py -f variant_file_with_line_delimited_dbSNPRN
```

The resulting output is formatted as a MINERVA's [genetic variant overlay file](https://minerva.pages.uni.lu/doc/user_manual/v14.0/index/#genetic-variant-format). An example follows:

```text
#NAME=DISEASE_ASSOCIATED_VARIANTS
#TYPE=GENETIC_VARIANT
#GENOME_TYPE=UCSC
#GENOME_VERSION=hg19
position	original_dna	alternative_dna	gene_name	description	color	contig	allele_frequency	amino_acid_change	identifier_uniprot
38592933	G	A	SCN5A	snv	#ff0000	3	0.8	SCN5A:XXX:g.38592933G>A:p.R1626C	H9KVD2
38592729	C	T	SCN5A	snv	#ff0000	3	0.8	SCN5A:XXX:g.38592729C>T:p.G1694S	H9KVD2
38627199	C	T	SCN5A	snv	#ff0000	3	0.8	SCN5A:XXX:g.38627199C>T:p.V924I	H9KVD2
38627199	C	A	SCN5A	snv	#ff0000	3	0.8	SCN5A:XXX:g.38627199C>A:p.V924F	H9KVD2
108867945	T	G	KCNE5	snv	#ff0000	X	0.8	KCNE5:XXX:g.108867945T>G:p.E102A	Q9UJ90
81667462	A	T	CACNA2D1	snv	#ff0000	7	0.8	CACNA2D1:XXX:g.81667462A>T:p.N323K	P54289-2 
...

```
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