</head> <body> Author: Muhammed Naveez, Riga Technical University, Latvia Description: Interactions of the SARS-CoV-2 Orf3a with human proteins, especially in the context of the HOPS Complex. </body> </html> </notes> <annotation> <celldesigner:extension> <celldesigner:modelVersion>4.0</celldesigner:modelVersion> <celldesigner:modelDisplay sizeX="1800" sizeY="2400"/> <celldesigner:listOfIncludedSpecies> <celldesigner:species id="s7" name="CLCC1"> <celldesigner:notes> <html xmlns="http://www.w3.org/1999/xhtml"> <head> <title/> </head> <body/> </html> </celldesigner:notes> <celldesigner:annotation> <celldesigner:complexSpecies>s8</celldesigner:complexSpecies> <celldesigner:speciesIdentity> <celldesigner:class>PROTEIN</celldesigner:class> <celldesigner:proteinReference>pr6</celldesigner:proteinReference> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> <celldesigner:species id="s9" name="Sun2"> <celldesigner:notes> <html xmlns="http://www.w3.org/1999/xhtml"> <head> <title/> </head> <body/> </html> </celldesigner:notes> <celldesigner:annotation> <celldesigner:complexSpecies>s8</celldesigner:complexSpecies> <celldesigner:speciesIdentity> <celldesigner:class>PROTEIN</celldesigner:class> <celldesigner:proteinReference>pr7</celldesigner:proteinReference> </celldesigner:speciesIdentity> </celldesigner:annotation> </celldesigner:species> <celldesigner:species id="s2" name="HMOX1"> <celldesigner:notes> <html xmlns="http://www.w3.org/1999/xhtml"> <head> <title/> </head> <body> https://chemrxiv.org/articles/COVID-19_Disease_ORF8_and_Surface_Glycoprotein_Inhibit_Heme_Metabolism_by_Binding_to_Porphyrin/11938173 COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism </body> </html> </celldesigner:notes> <celldesigner:annotation> <celldesigner:complexSpecies>s8</celldesigner:complexSpecies> <celldesigner:speciesIdentity> 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