# Generated by CaSQ v0.9.6 Nrf2/Maf_complex POSITIVE HMOX1_rna NRF2_phosphorylated_Nucleus POSITIVE Nrf2/Maf_complex NRF2_phosphorylated_Nucleus POSITIVE SLC40A1_rna NRF2_phosphorylated_Nucleus POSITIVE FTH1_rna NRF2_phosphorylated_Nucleus POSITIVE FTL_rna NRF2_phosphorylated_Nucleus POSITIVE FECH_rna NRF2_phosphorylated_Nucleus POSITIVE BLVRA_rna NRF2_phosphorylated_Nucleus POSITIVE BLVRB_rna MAF POSITIVE Nrf2/Maf_complex MAF POSITIVE BACH1/Maf_complex BACH1/Maf_complex NEGATIVE HMOX1_rna BACH1 POSITIVE BACH1/Maf_complex Ubiquitin_Ligase_Complex_complex_Cytosol POSITIVE Ubiquitin_Ligase_Complex_complex_Cytosol CAND1 NEGATIVE Ubiquitin_Ligase_Complex_complex_Cytosol CUL3:RBX1_complex POSITIVE Ubiquitin_Ligase_Complex_complex_Cytosol NRF2_empty POSITIVE Ubiquitin_Ligase_Complex_complex_Cytosol NRF2_empty POSITIVE NRF2_phosphorylated_Cytosol KEAP1 POSITIVE Ubiquitin_Ligase_Complex_complex_Cytosol Dimethly_fumarate_drug NEGATIVE Ubiquitin_Ligase_Complex_complex_Cytosol Ubiquitin_Ligase_Complex_complex_Cytosol POSITIVE Ubiquitin_Ligase_Complex_complex_Cytosol Ubiquitin_Ligase_Complex_complex_Cytosol POSITIVE NRF2_ubiquitinated SLC40A1:CP:Cu2+_complex POSITIVE Fe2+_ion_default_compartment SLC40A1:CP:Cu2+_complex POSITIVE Fe3+_ion_default_compartment SLC40A1:CP:Cu2+_complex POSITIVE H2O_simple_molecule_default_compartment SLC40A1_rna POSITIVE SLC40A1:CP:Cu2+_complex TFRC:holoTF_complex_Cytosol POSITIVE TFRC:holoTF_complex_Endosome_Lumen TFRC:TF_complex_Cytosol POSITIVE TFRC:holoTF_complex_Cytosol TFRC:TF_complex_Cytosol POSITIVE Transferrin Fe3+_ion_default_compartment POSITIVE TFRC:holoTF_complex_Cytosol Fe3+_ion_default_compartment POSITIVE Fe2+_ion_default_compartment Transferrin POSITIVE TFRC:holoTF_complex_Cytosol TFRC:holoTF_complex_Endosome_Lumen POSITIVE TFRC:TF_complex_Endosome_Lumen TFRC:holoTF_complex_Endosome_Lumen POSITIVE Fe3+_ion_Endosome_Lumen TFRC:TF_complex_Endosome_Lumen POSITIVE TFRC:TF_complex_Cytosol TXNIP:NLRP3_complex POSITIVE NLRP3_Cytosol_active NLRP3_Cytosol POSITIVE TXNIP:NLRP3_complex NLRP3_Cytosol POSITIVE NLRP3_Cytosol_active TXNIP POSITIVE TXNIP:NLRP3_complex TXNIP POSITIVE Thioredoxin:TXNIP_complex NLRP3:SUGT1:HSP90_complex POSITIVE NLRP3:SUGT1:HSP90_complex NLRP3:SUGT1:HSP90_complex POSITIVE NLRP3_Cytosol NLRP3_rna POSITIVE NLRP3:SUGT1:HSP90_complex BLVRA:Zn2+_complex POSITIVE NADP+_simple_molecule BLVRA:Zn2+_complex POSITIVE Bilirubin_simple_molecule BLVRA_rna POSITIVE BLVRA:Zn2+_complex Thioredoxin:TXNIP_complex POSITIVE TXNIP Thioredoxin:TXNIP_complex POSITIVE TXN_Cytosol TXN_Cytosol POSITIVE Thioredoxin:TXNIP_complex TXN_Cytosol POSITIVE TXN_Cytosol Pyrin_trimer_complex POSITIVE PSTPIP1_trimer:Pyrin_trimer_complex Pyrin_trimer_complex POSITIVE Pyrin_trimer:ASC_complex PSTPIP1 POSITIVE PSTPIP1_trimer:Pyrin_trimer_complex ASC POSITIVE Pyrin_trimer:ASC_complex ASC POSITIVE NLRP3_oligomer:ASC:Caspase1_complex NLRP3_oligomer:ASC:Caspase1_complex POSITIVE NLRP3_oligomer:ASC:Caspase1_complex NLRP3_oligomer:ASC:Caspase1_complex POSITIVE CASP1(120-197):CASP1(317-404)_complex NLRP3_oligomer:ASC:Caspase1_complex POSITIVE CASP1_Cytosol NLRP3_oligomer:ASC:Caspase1_complex POSITIVE CASP1_Cytosol NLRP3_Cytosol_active POSITIVE NLRP3_oligomer:ASC:Caspase1_complex CTSG POSITIVE NLRP3_oligomer:ASC:Caspase1_complex CTSG POSITIVE CASP1(120-197):CASP1(317-404)_complex CTSG POSITIVE CASP1_Cytosol CTSG POSITIVE CASP1_Cytosol Ferritin_complex POSITIVE Fe(3+)O(OH)_simple_molecule FTH1_rna POSITIVE Ferritin_complex FTL_rna POSITIVE Ferritin_complex Bilirubin_simple_molecule POSITIVE ALB/BIL_complex ABCC1 POSITIVE ALB/BIL_complex Caspase-1_Tetramer_complex POSITIVE proIL-1B_Cytosol Caspase-1_Tetramer_complex POSITIVE proIL-18_Cytosol Caspase-1_Tetramer_complex POSITIVE IL-1B_Cytosol Caspase-1_Tetramer_complex POSITIVE IL-18_Cytosol CASP1(120-197):CASP1(317-404)_complex POSITIVE Caspase-1_Tetramer_complex Heme_simple_molecule_Cytosol POSITIVE Biliverdin_simple_molecule Heme_simple_molecule_Cytosol POSITIVE H2O_simple_molecule_Cytosol Heme_simple_molecule_Cytosol POSITIVE NADP+_simple_molecule Heme_simple_molecule_Cytosol POSITIVE Fe2+_ion_Cytosol Heme_simple_molecule_Cytosol POSITIVE CO_simple_molecule Heme_simple_molecule_Cytosol POSITIVE Heme_simple_molecule_default_compartment Heme_simple_molecule_Cytosol POSITIVE ADP_simple_molecule Heme_simple_molecule_Cytosol POSITIVE Pi_simple_molecule Heme_simple_molecule_Mitochondrial_Matrix POSITIVE Heme_simple_molecule_Cytosol Heme_simple_molecule_Mitochondrial_Matrix NEGATIVE dALA_simple_molecule_Mitochondrial_Matrix Heme_simple_molecule_Mitochondrial_Matrix NEGATIVE CO2_simple_molecule_Mitochondrial_Matrix Heme_simple_molecule_Mitochondrial_Matrix NEGATIVE CoA-SH_simple_molecule FLVCR1-2 POSITIVE Heme_simple_molecule_Cytosol Biliverdin_simple_molecule POSITIVE NADP+_simple_molecule Biliverdin_simple_molecule POSITIVE Bilirubin_simple_molecule O2_simple_molecule_Cytosol POSITIVE Biliverdin_simple_molecule O2_simple_molecule_Cytosol POSITIVE H2O_simple_molecule_Cytosol O2_simple_molecule_Cytosol POSITIVE NADP+_simple_molecule O2_simple_molecule_Cytosol POSITIVE Fe2+_ion_Cytosol O2_simple_molecule_Cytosol POSITIVE CO_simple_molecule O2_simple_molecule_Cytosol POSITIVE Fe(3+)O(OH)_simple_molecule NADPH_simple_molecule POSITIVE Biliverdin_simple_molecule NADPH_simple_molecule POSITIVE H2O_simple_molecule_Cytosol NADPH_simple_molecule POSITIVE NADP+_simple_molecule NADPH_simple_molecule POSITIVE Fe2+_ion_Cytosol NADPH_simple_molecule POSITIVE CO_simple_molecule NADPH_simple_molecule POSITIVE Bilirubin_simple_molecule HMOX1_Cytosol_active POSITIVE Biliverdin_simple_molecule HMOX1_Cytosol_active POSITIVE H2O_simple_molecule_Cytosol HMOX1_Cytosol_active POSITIVE NADP+_simple_molecule HMOX1_Cytosol_active POSITIVE Fe2+_ion_Cytosol HMOX1_Cytosol_active POSITIVE CO_simple_molecule PRIN9_simple_molecule_Mitochondrial_Matrix POSITIVE Heme_simple_molecule_Mitochondrial_Matrix PRIN9_simple_molecule_Mitochondrial_Matrix POSITIVE H+_ion_Mitochondrial_Matrix Fe2+_ion_Mitochondrial_Matrix POSITIVE Heme_simple_molecule_Mitochondrial_Matrix Fe2+_ion_Mitochondrial_Matrix POSITIVE H+_ion_Mitochondrial_Matrix FECH POSITIVE Heme_simple_molecule_Mitochondrial_Matrix FECH POSITIVE H+_ion_Mitochondrial_Matrix Pb2+_ion NEGATIVE Heme_simple_molecule_Mitochondrial_Matrix Pb2+_ion NEGATIVE H+_ion_Mitochondrial_Matrix H2O_simple_molecule_Cytosol POSITIVE HMBL_simple_molecule H2O_simple_molecule_Cytosol POSITIVE NH4+_ion H2O_simple_molecule_Cytosol POSITIVE Heme_simple_molecule_default_compartment H2O_simple_molecule_Cytosol POSITIVE ADP_simple_molecule H2O_simple_molecule_Cytosol POSITIVE Pi_simple_molecule dALA_simple_molecule_Cytosol POSITIVE H2O_simple_molecule_Cytosol dALA_simple_molecule_Cytosol POSITIVE PBG_simple_molecule dALA_simple_molecule_Cytosol POSITIVE H+_ion_Cytosol ALAD:Zn2+_complex POSITIVE H2O_simple_molecule_Cytosol ALAD:Zn2+_complex POSITIVE PBG_simple_molecule ALAD:Zn2+_complex POSITIVE H+_ion_Cytosol BLVRB POSITIVE NADP+_simple_molecule BLVRB POSITIVE Bilirubin_simple_molecule Fe2+_ion_Cytosol POSITIVE Fe2+_ion_Cytosol Fe2+_ion_Cytosol POSITIVE Fe2+_ion_default_compartment Fe2+_ion_Cytosol POSITIVE Fe(3+)O(OH)_simple_molecule Fe2+_ion_Cytosol POSITIVE Reactive_Oxygen_Species_simple_molecule Fe2+_ion_default_compartment POSITIVE Fe2+_ion_Cytosol Fe2+_ion_default_compartment POSITIVE Fe3+_ion_default_compartment Fe2+_ion_default_compartment POSITIVE H2O_simple_molecule_default_compartment SLC11A2 POSITIVE Fe2+_ion_Cytosol Fe2+_ion_Endosome_Lumen POSITIVE Fe2+_ion_Cytosol MCOLN1 POSITIVE Fe2+_ion_Cytosol HMOX1_Cytosol POSITIVE HMOX1_Cytosol_active HMOX1_rna POSITIVE HMOX1_Cytosol CO_simple_molecule NEGATIVE Reactive_Oxygen_Species_simple_molecule BLVRB_rna POSITIVE BLVRB ORF9c POSITIVE ABCC1 NRF2_phosphorylated_Cytosol POSITIVE NRF2_phosphorylated_Nucleus miRNA-155_rna NEGATIVE BACH1 FECH_rna POSITIVE FECH PRIN9_simple_molecule_Mitochondrion POSITIVE PRIN9_simple_molecule_Mitochondrial_Matrix H+_ion_Mitochondrial_Matrix POSITIVE dALA_simple_molecule_Mitochondrial_Matrix H+_ion_Mitochondrial_Matrix POSITIVE CO2_simple_molecule_Mitochondrial_Matrix H+_ion_Mitochondrial_Matrix POSITIVE CoA-SH_simple_molecule dALA_simple_molecule_Mitochondrial_Matrix POSITIVE dALA_simple_molecule_Cytosol SUCC-CoA_simple_molecule POSITIVE dALA_simple_molecule_Mitochondrial_Matrix SUCC-CoA_simple_molecule POSITIVE CO2_simple_molecule_Mitochondrial_Matrix SUCC-CoA_simple_molecule POSITIVE CoA-SH_simple_molecule Gly_simple_molecule POSITIVE dALA_simple_molecule_Mitochondrial_Matrix Gly_simple_molecule POSITIVE CO2_simple_molecule_Mitochondrial_Matrix Gly_simple_molecule POSITIVE CoA-SH_simple_molecule ALAS1:ALAS2_complex POSITIVE dALA_simple_molecule_Mitochondrial_Matrix ALAS1:ALAS2_complex POSITIVE CO2_simple_molecule_Mitochondrial_Matrix ALAS1:ALAS2_complex POSITIVE CoA-SH_simple_molecule Panhematin_drug NEGATIVE dALA_simple_molecule_Mitochondrial_Matrix Panhematin_drug NEGATIVE CO2_simple_molecule_Mitochondrial_Matrix Panhematin_drug NEGATIVE CoA-SH_simple_molecule PBG_simple_molecule POSITIVE HMBL_simple_molecule PBG_simple_molecule POSITIVE NH4+_ion H+_ion_Cytosol POSITIVE Fe(3+)O(OH)_simple_molecule HMBL_simple_molecule POSITIVE URO3_simple_molecule HMBS:DIPY_complex POSITIVE HMBL_simple_molecule HMBS:DIPY_complex POSITIVE NH4+_ion URO3_simple_molecule POSITIVE COPRO3_simple_molecule_Cytosol UROS POSITIVE URO3_simple_molecule COPRO3_simple_molecule_Cytosol POSITIVE COPRO3_simple_molecule_Mitochondrion UROD POSITIVE COPRO3_simple_molecule_Cytosol COPRO3_simple_molecule_Mitochondrion POSITIVE PPGEN9_simple_molecule COPRO3_simple_molecule_Mitochondrion POSITIVE CO2_simple_molecule_Mitochondrion COPRO3_simple_molecule_Mitochondrion POSITIVE H2O2_simple_molecule PPGEN9_simple_molecule POSITIVE PRIN9_simple_molecule_Mitochondrion PPGEN9_simple_molecule POSITIVE H2O2_simple_molecule O2_simple_molecule_Mitochondrion POSITIVE PPGEN9_simple_molecule O2_simple_molecule_Mitochondrion POSITIVE PRIN9_simple_molecule_Mitochondrion O2_simple_molecule_Mitochondrion POSITIVE CO2_simple_molecule_Mitochondrion O2_simple_molecule_Mitochondrion POSITIVE H2O2_simple_molecule CPOX POSITIVE PPGEN9_simple_molecule CPOX POSITIVE CO2_simple_molecule_Mitochondrion CPOX POSITIVE H2O2_simple_molecule PPO:FAD_complex POSITIVE PRIN9_simple_molecule_Mitochondrion PPO:FAD_complex POSITIVE H2O2_simple_molecule Lipid_Peroxide_simple_molecule POSITIVE Ferroptosis_phenotype Lipid_Peroxide_simple_molecule POSITIVE Lipid_alcohol_simple_molecule Poly-unsaturated_fatty_acid_simple_molecule POSITIVE Lipid_Peroxide_simple_molecule Reactive_Oxygen_Species_simple_molecule POSITIVE Lipid_Peroxide_simple_molecule Reactive_Oxygen_Species_simple_molecule POSITIVE TXNIP Reactive_Oxygen_Species_simple_molecule POSITIVE TXN_Cytosol Reactive_Oxygen_Species_simple_molecule POSITIVE NLRP3_Cytosol_active SLC40A1:HEPH:Cu2+_complex POSITIVE Fe2+_ion_default_compartment SLC40A1:HEPH:Cu2+_complex POSITIVE Fe3+_ion_default_compartment SLC40A1:HEPH:Cu2+_complex POSITIVE H2O_simple_molecule_default_compartment e-_ion_default_compartment POSITIVE Fe2+_ion_default_compartment CYBRD1:Heme_complex POSITIVE Fe2+_ion_default_compartment O2_simple_molecule_default_compartment POSITIVE Fe3+_ion_default_compartment O2_simple_molecule_default_compartment POSITIVE H2O_simple_molecule_default_compartment H+_ion_default_compartment POSITIVE Fe3+_ion_default_compartment H+_ion_default_compartment POSITIVE H2O_simple_molecule_default_compartment GPX4 POSITIVE Lipid_alcohol_simple_molecule ORF3a POSITIVE HMOX1_Cytosol_active PKC POSITIVE NRF2_phosphorylated_Cytosol CK2 POSITIVE NRF2_phosphorylated_Cytosol FLVCR1-1 POSITIVE Heme_simple_molecule_default_compartment ATP_simple_molecule POSITIVE Heme_simple_molecule_default_compartment ATP_simple_molecule POSITIVE ADP_simple_molecule ATP_simple_molecule POSITIVE Pi_simple_molecule ABCG2 POSITIVE Heme_simple_molecule_default_compartment ABCG2 POSITIVE ADP_simple_molecule ABCG2 POSITIVE Pi_simple_molecule Fe3+_ion_Endosome_Lumen POSITIVE Fe2+_ion_Endosome_Lumen e-_ion_Endosome_Lumen POSITIVE Fe2+_ion_Endosome_Lumen STEAP3 POSITIVE Fe2+_ion_Endosome_Lumen Nf-KB_Complex_complex POSITIVE NLRP3_rna proIL-1B_Cytosol POSITIVE proIL-1B_Cytosol proIL-1B_Cytosol POSITIVE IL-1B_Cytosol proIL-18_Cytosol POSITIVE proIL-18_Cytosol proIL-18_Cytosol POSITIVE IL-18_Cytosol IL-1B_Cytosol POSITIVE IL-1B_default_compartment IL-18_Cytosol POSITIVE IL-18_default_compartment SARS_E POSITIVE NLRP3_Cytosol_active PAMPs_phenotype POSITIVE NLRP3_Cytosol_active DAMPs_phenotype POSITIVE NLRP3_Cytosol_active SARS_Orf3a POSITIVE NLRP3_Cytosol_active NLRP3_Elicitor_Small_Molecules_simple_molecule POSITIVE NLRP3_Cytosol_active NLRP3_Elicitor_Proteins POSITIVE NLRP3_Cytosol_active