PAMP_Gene Prioritization.tsv 1.54 KB
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Rank	Gene Symbol	Definition	Systemic Processes	Interactions	Drugs
1	CHUK	conserved helix-loop-helix ubiquitous kinase	9	14	5
2	IRAK1	interleukin 1 receptor associated kinase 1	9	9	0
3	MYD88	"MYD88, innate immune signal transduction adaptor"	9	11	0
4	IKBKG	inhibitor of nuclear factor kappa B kinase subunit gamma	8	18	7
5	DDX58	DExD/H-box helicase 58	8	7	0
6	IKBKB	inhibitor of nuclear factor kappa B kinase subunit beta	8	15	9
7	TLR3	toll like receptor 3	8	11	1
8	TLR7	toll like receptor 7	8	1	11
9	IKBKE	inhibitor of nuclear factor kappa B kinase subunit epsilon	7	13	0
10	TICAM1	toll like receptor adaptor molecule 1	7	12	0
11	TBK1	TANK binding kinase 1	7	14	0
12	MAP3K7	mitogen-activated protein kinase kinase kinase 7	7	19	0
13	RIPK1	receptor interacting serine/threonine kinase 1	7	15	0
14	TRAF6	TNF receptor associated factor 6	7	24	0
15	TLR8	toll like receptor 8	7	0	4
16	MAVS	mitochondrial antiviral signaling protein	7	19	0
17	IFIH1	interferon induced with helicase C domain 1	6	1	0
18	ITCH	itchy E3 ubiquitin protein ligase	6	8	0
19	FADD	Fas associated via death domain	6	11	0
20	IRAK4	interleukin 1 receptor associated kinase 4	6	4	1
21	IRF3	interferon regulatory factor 3	6	13	0
22	IRF7	interferon regulatory factor 7	6	8	0
23	UBE2N	ubiquitin conjugating enzyme E2 N	6	5	0
24	MAPK14	mitogen-activated protein kinase 14	5	11	62
25	TRADD	TNFRSF1A associated via death domain	5	6	0
26	TRAF2	TNF receptor associated factor 2	5	22	0
27	TRIM25	tripartite motif containing 25	5	10	0
28	CASP8	caspase 8	5	12	0
29	MAP2K6	mitogen-activated protein kinase kinase 6	5	6	1