Pyrimidine_deprivation_stable.sif 7.28 KB
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# Generated by CaSQ v0.9.5
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IFNB1_space_expression_space_complex_complex POSITIVE IFNA1_rna
IFNB1_space_expression_space_complex_complex POSITIVE IFNB1_rna
NF-kB_complex POSITIVE IFNB1_space_expression_space_complex_complex
IRF3_phosphorylated POSITIVE IFNB1_space_expression_space_complex_complex
cGAMP:STING_complex_Perinuclear_space_Golgi POSITIVE STING:TBK1_complex_Perinuclear_space_Golgi
cGAMP:STING_complex_Endoplamatic_space_reticulum POSITIVE cGAMP:STING_complex_Perinuclear_space_Golgi
cGAMP:STING_complex_Endoplamatic_space_reticulum POSITIVE cGAMP-STING_complex
cGAMP_simple_molecule POSITIVE cGAMP:STING_complex_Endoplamatic_space_reticulum
STING_Endoplamatic_space_reticulum POSITIVE cGAMP:STING_complex_Endoplamatic_space_reticulum
STING_Endoplamatic_space_reticulum POSITIVE STING_Perinuclear_space_Golgi
cGAMP:STING:LC3_complex POSITIVE HCoVs_autophagy_(WP4863)_phenotype
WIPI2 POSITIVE cGAMP:STING:LC3_complex
cGAMP-STING_complex POSITIVE cGAMP:STING:LC3_complex
cGAS:dsDNA_complex POSITIVE cGAMP_simple_molecule
dsDNA_simple_molecule POSITIVE cGAS:dsDNA_complex
dsDNA_simple_molecule POSITIVE MRE11:RAD50:DNA_complex_Pulmonary_space_endothelial_space_cell
dsDNA_simple_molecule POSITIVE DNA_gene
cGAS POSITIVE cGAS:dsDNA_complex
STING:TBK1_complex_Perinuclear_space_Golgi POSITIVE STING:TBK1_complex_Endolysozome
TBK1 POSITIVE STING:TBK1_complex_Perinuclear_space_Golgi
STING_Perinuclear_space_Golgi POSITIVE STING:TBK1_complex_Perinuclear_space_Golgi
SAR1A POSITIVE cGAMP-STING_complex
STING:TBK1_complex_Endolysozome POSITIVE IRF3_phosphorylated
MRE11:RAD50:DNA_complex_Endoplamatic_space_reticulum POSITIVE STING_Perinuclear_space_Golgi
MRE11:RAD50:DNA_complex_Pulmonary_space_endothelial_space_cell POSITIVE MRE11:RAD50:DNA_complex_Endoplamatic_space_reticulum
MRE11 POSITIVE MRE11:RAD50:DNA_complex_Pulmonary_space_endothelial_space_cell
cytidine_simple_molecule POSITIVE CMP_simple_molecule
cytidine_simple_molecule POSITIVE uridine_simple_molecule
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H2O_simple_molecule POSITIVE Pi_simple_molecule
H2O_simple_molecule POSITIVE ADP_simple_molecule
H2O_simple_molecule POSITIVE L-Glu_simple_molecule
H2O_simple_molecule POSITIVE CAP_simple_molecule
N-carbamoyl-L-aspartate_simple_molecule POSITIVE H2O_simple_molecule
N-carbamoyl-L-aspartate_simple_molecule POSITIVE (S)-dihydroorotate_simple_molecule
H+simple_molecule POSITIVE H2O_simple_molecule
H+simple_molecule POSITIVE (S)-dihydroorotate_simple_molecule
CAD POSITIVE H2O_simple_molecule
CAD POSITIVE Pi_simple_molecule
CAD POSITIVE (S)-dihydroorotate_simple_molecule
CAD POSITIVE ADP_simple_molecule
CAD POSITIVE N-carbamoyl-L-aspartate_simple_molecule
CAD POSITIVE L-Glu_simple_molecule
CAD POSITIVE CAP_simple_molecule
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UMP_simple_molecule POSITIVE UDP_simple_molecule
uridine_simple_molecule POSITIVE UMP_simple_molecule
UCK2 POSITIVE UMP_simple_molecule
UCK2 POSITIVE CMP_simple_molecule
orotidine_space_5'-monophosphate_simple_molecule POSITIVE UMP_simple_molecule
orotidine_space_5'-monophosphate_simple_molecule POSITIVE CO2_simple_molecule
UMPS POSITIVE UMP_simple_molecule
UMPS POSITIVE PPi_simple_molecule
UMPS POSITIVE orotidine_space_5'-monophosphate_simple_molecule
UMPS POSITIVE CO2_simple_molecule
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ATP_simple_molecule POSITIVE cGAMP_simple_molecule
ATP_simple_molecule POSITIVE Pi_simple_molecule
ATP_simple_molecule POSITIVE ADP_simple_molecule
ATP_simple_molecule POSITIVE L-Glu_simple_molecule
ATP_simple_molecule POSITIVE CAP_simple_molecule
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GTP_simple_molecule POSITIVE cGAMP_simple_molecule
RTC_and_transcription_pw_phenotype POSITIVE RNA_space_biosynthesis_phenotype
dCDP_simple_molecule POSITIVE dCTP_simple_molecule
CDP_simple_molecule POSITIVE dCDP_simple_molecule
CDP_simple_molecule POSITIVE CTP_simple_molecule
ribonucleoside-diphosphate_reductase_complex POSITIVE dCDP_simple_molecule
ribonucleoside-diphosphate_reductase_complex POSITIVE dUDP_simple_molecule
UDP_simple_molecule POSITIVE UTP_simple_molecule
UDP_simple_molecule POSITIVE dUDP_simple_molecule
CMPK POSITIVE UDP_simple_molecule
CMPK POSITIVE CDP_simple_molecule
dTMP_simple_molecule POSITIVE dTDP_simple_molecule
dUMP_simple_molecule POSITIVE dTMP_simple_molecule
TYMS POSITIVE dTMP_simple_molecule
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IFNA1_Pulmonary_space_endothelial_space_cell POSITIVE IFNA1_default_compartment
IFNA1_rna POSITIVE IFNA1_Pulmonary_space_endothelial_space_cell
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L-Gln_simple_molecule POSITIVE Pi_simple_molecule
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L-Gln_simple_molecule POSITIVE ADP_simple_molecule
L-Gln_simple_molecule POSITIVE L-Glu_simple_molecule
L-Gln_simple_molecule POSITIVE CAP_simple_molecule
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HCO3-simple_molecule POSITIVE Pi_simple_molecule
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HCO3-simple_molecule POSITIVE ADP_simple_molecule
HCO3-simple_molecule POSITIVE L-Glu_simple_molecule
HCO3-simple_molecule POSITIVE CAP_simple_molecule
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CAP_simple_molecule POSITIVE Pi_simple_molecule
CAP_simple_molecule POSITIVE N-carbamoyl-L-aspartate_simple_molecule
L-Asp_simple_molecule POSITIVE Pi_simple_molecule
L-Asp_simple_molecule POSITIVE N-carbamoyl-L-aspartate_simple_molecule
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(S)-dihydroorotate_simple_molecule POSITIVE QH2_simple_molecule
(S)-dihydroorotate_simple_molecule POSITIVE orotate_simple_molecule
dUTP_simple_molecule POSITIVE dUMP_simple_molecule
DUT POSITIVE dUMP_simple_molecule
dCMP_simple_molecule POSITIVE dUMP_simple_molecule
DCTD POSITIVE dUMP_simple_molecule
CMP_simple_molecule POSITIVE CDP_simple_molecule
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IFNB1_default_compartment POSITIVE HCoVs_Type_I_Ifn_signalling(WP4868)_phenotype
IFNB1_default_compartment POSITIVE Interferon_1_pathway_phenotype
IFNB1_default_compartment POSITIVE HCoVs_IFN_induction_WP4880_phenotype
IFNB1_Pulmonary_space_endothelial_space_cell POSITIVE IFNB1_default_compartment
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dTTP_simple_molecule POSITIVE DNA_gene
DNA_space_biosynthesis_phenotype POSITIVE DNA_gene
virus_space_replication_phenotype NEGATIVE DNA_gene
dTDP_simple_molecule POSITIVE dTTP_simple_molecule
dTYMK POSITIVE dTDP_simple_molecule
DNA_damage_phenotype POSITIVE dsDNA_simple_molecule
UTP_simple_molecule POSITIVE CTP_simple_molecule
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NME1 POSITIVE UTP_simple_molecule
NME1 POSITIVE dCTP_simple_molecule
NME1 POSITIVE dUTP_simple_molecule
NME1 POSITIVE CTP_simple_molecule
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orotate_simple_molecule POSITIVE PPi_simple_molecule
orotate_simple_molecule POSITIVE orotidine_space_5'-monophosphate_simple_molecule
PRPP_simple_molecule POSITIVE PPi_simple_molecule
PRPP_simple_molecule POSITIVE orotidine_space_5'-monophosphate_simple_molecule
CDA POSITIVE uridine_simple_molecule
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IFNB1_rna POSITIVE IFNB1_Pulmonary_space_endothelial_space_cell
IFNA1_default_compartment POSITIVE HCoVs_Type_I_Ifn_signalling(WP4868)_phenotype
IFNA1_default_compartment POSITIVE Interferon_1_pathway_phenotype
IFNA1_default_compartment POSITIVE HCoVs_IFN_induction_WP4880_phenotype
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dCTP_simple_molecule POSITIVE dCMP_simple_molecule
DCTPP1 POSITIVE dCMP_simple_molecule
CoQ_simple_molecule POSITIVE QH2_simple_molecule
CoQ_simple_molecule POSITIVE orotate_simple_molecule
dihydroorotate_space_dehydrogenase_space_holoenzyme_simple_molecule POSITIVE QH2_simple_molecule
dihydroorotate_space_dehydrogenase_space_holoenzyme_simple_molecule POSITIVE orotate_simple_molecule
P1788_simple_molecule NEGATIVE QH2_simple_molecule
P1788_simple_molecule NEGATIVE orotate_simple_molecule
Teriflunomide_drug NEGATIVE QH2_simple_molecule
Teriflunomide_drug NEGATIVE orotate_simple_molecule
Teriflunomide_drug POSITIVE DNA_damage_phenotype
dUDP_simple_molecule POSITIVE dUTP_simple_molecule
CTP_simple_molecule POSITIVE RTC_and_transcription_pw_phenotype
CTPS1 POSITIVE CTP_simple_molecule