NLRP3_Activation_stable.sif 4.64 KB
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# Generated by CaSQ v0.9.7
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ASC:MAVS:TRAF3_complex_Cytosol POSITIVE ASC:MAVS:TRAF3_complex_Cytosol
ASC:MAVS_complex POSITIVE ASC:MAVS:TRAF3_complex_Cytosol
TRAF3 POSITIVE ASC:MAVS:TRAF3_complex_Cytosol
TRAF3 POSITIVE TRAF3:SARS_Orf3a_complex_Cytosol
NLRP3:SUGT1:HSP90_complex POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
NLRP3:SUGT1:HSP90_complex POSITIVE SUGT1:HSP90AB1_complex
NLRP3 POSITIVE NLRP3:SUGT1:HSP90_complex
NLRP3 POSITIVE TXNIP:NLRP3_complex
SUGT1:HSP90AB1_complex POSITIVE NLRP3:SUGT1:HSP90_complex
TRAF3:SARS_Orf3a_complex_Cytosol POSITIVE p105_ubiquitinated
NLRP3_oligomer:ASC:proCaspase1_complex POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
NLRP3_oligomer:ASC:proCaspase1_complex POSITIVE CASP1(120-197):CASP1(317-404)_complex
NLRP3_oligomer:ASC:proCaspase1_complex POSITIVE CASP1_Cytosol
NLRP3_oligomer:ASC:proCaspase1_complex POSITIVE CASP1_Cytosol
CTSG POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
CTSG POSITIVE CASP1(120-197):CASP1(317-404)_complex
CTSG POSITIVE CASP1_Cytosol
CTSG POSITIVE CASP1_Cytosol
ASC:MAVS:TRAF3_complex_Cytosol POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
ASC:MAVS:TRAF3_complex_Cytosol POSITIVE TRAF3
ASC:MAVS:TRAF3_complex_Cytosol POSITIVE MAVS
DAMPs_phenotype POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
DAMPs_phenotype POSITIVE SUGT1:HSP90AB1_complex
PAMPs_phenotype POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
PAMPs_phenotype POSITIVE SUGT1:HSP90AB1_complex
NLRP3_Elicitor_Small_Molecules_simple_molecule POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
NLRP3_Elicitor_Small_Molecules_simple_molecule POSITIVE SUGT1:HSP90AB1_complex
NLRP3_Elicitor_Proteins POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
NLRP3_Elicitor_Proteins POSITIVE SUGT1:HSP90AB1_complex
Reactive_Oxygen_Species_simple_molecule POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
Reactive_Oxygen_Species_simple_molecule POSITIVE SUGT1:HSP90AB1_complex
Reactive_Oxygen_Species_simple_molecule POSITIVE TXN_Cytosol
TXNIP:NLRP3_complex POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
TXNIP:NLRP3_complex POSITIVE SUGT1:HSP90AB1_complex
Ca2+_ion POSITIVE NLRP3_oligomer:ASC:proCaspase1_complex
Ca2+_ion POSITIVE SUGT1:HSP90AB1_complex
Caspase-1_Tetramer_complex POSITIVE IL-18_Cytosol
Caspase-1_Tetramer_complex POSITIVE IL-1B_Cytosol
Caspase-1_Tetramer_complex POSITIVE proIL-18_Cytosol
Caspase-1_Tetramer_complex POSITIVE proIL-1B_Cytosol
CASP1(120-197):CASP1(317-404)_complex POSITIVE Caspase-1_Tetramer_complex
TXNIP POSITIVE TXNIP:NLRP3_complex
TXNIP POSITIVE Thioredoxin:TXNIP_complex
TRAF3:SARS_Orf3a_complex_Cytosol POSITIVE ASC:MAVS:TRAF3_complex_Cytosol
NF-KB_COMPLEX:IKBA_complex NEGATIVE Nf-KB_Complex_complex_Nucleoplasm
IKBA_phosphorylated_phosphorylated POSITIVE NF-KB_COMPLEX:IKBA_complex
Nf-KB_Complex_complex_Cytosol POSITIVE NF-KB_COMPLEX:IKBA_complex
Nf-KB_Complex_complex_Cytosol POSITIVE Nf-KB_Complex_complex_Nucleoplasm
p50 POSITIVE Nf-KB_Complex_complex_Cytosol
p65 POSITIVE Nf-KB_Complex_complex_Cytosol
Nf-KB_Complex_complex_Nucleoplasm POSITIVE proIL-18_rna
Nf-KB_Complex_complex_Nucleoplasm POSITIVE proIL-1B_rna
Thioredoxin:TXNIP_complex POSITIVE TXNIP
Thioredoxin:TXNIP_complex POSITIVE TXN_Cytosol
TXN_Cytosol POSITIVE Thioredoxin:TXNIP_complex
TXN_Cytosol POSITIVE TXN_Cytosol
ASC POSITIVE ASC:MAVS_complex
MAVS POSITIVE ASC:MAVS_complex
Orf3a POSITIVE TRAF3:SARS_Orf3a_complex_Cytosol
CO_simple_molecule NEGATIVE Reactive_Oxygen_Species_simple_molecule
proIL-18_Cytosol POSITIVE IL-18_Cytosol
proIL-18_Cytosol POSITIVE proIL-18_Cytosol
proIL-18_rna POSITIVE proIL-18_Cytosol
proIL-1B_Cytosol POSITIVE IL-1B_Cytosol
proIL-1B_Cytosol POSITIVE proIL-1B_Cytosol
proIL-1B_rna POSITIVE proIL-1B_Cytosol
IL-18_Cytosol POSITIVE IL-18_default_compartment
IL-1B_Cytosol POSITIVE IL-1B_default_compartment
p105_ubiquitinated POSITIVE p50
E_Golgi POSITIVE Ca2+_ion
E_ERGIC POSITIVE Ca2+_ion
Heme_simple_molecule POSITIVE NADP+_simple_molecule
Heme_simple_molecule POSITIVE Biliverdin_simple_molecule
Heme_simple_molecule POSITIVE H2O_simple_molecule
Heme_simple_molecule POSITIVE CO_simple_molecule
Heme_simple_molecule POSITIVE Fe2+_ion
O2_simple_molecule POSITIVE NADP+_simple_molecule
O2_simple_molecule POSITIVE Biliverdin_simple_molecule
O2_simple_molecule POSITIVE H2O_simple_molecule
O2_simple_molecule POSITIVE CO_simple_molecule
O2_simple_molecule POSITIVE Fe2+_ion
NADPH_simple_molecule POSITIVE NADP+_simple_molecule
NADPH_simple_molecule POSITIVE Biliverdin_simple_molecule
NADPH_simple_molecule POSITIVE H2O_simple_molecule
NADPH_simple_molecule POSITIVE CO_simple_molecule
NADPH_simple_molecule POSITIVE Fe2+_ion
HMOX1 POSITIVE NADP+_simple_molecule
HMOX1 POSITIVE Biliverdin_simple_molecule
HMOX1 POSITIVE H2O_simple_molecule
HMOX1 POSITIVE CO_simple_molecule
HMOX1 POSITIVE Fe2+_ion