Updated README with latest manuscript details.
|...||...||@@ -23,6 +23,7 @@ The workflow is split into eight sequential steps, each one is associated with a|
|6. The meta-analyses are performed by integrating the results of the differential expression analyses across datasets (again separately for each sex). By comparing the male and female results, the female-specific, male-specific and sex-dimorphic genes are then defined.|
|7. Functional enrichment of the meta-analysis results is performed.|
|8. Regulatory networks around the key differentially expressed genes are reconstructed.|
|9. The processing and analysis of single-cell RNA sequencing datasets for validation purposes.|
|The datasets used in our study have been extracted from the [Gene Expression Omnibus](https://www.ncbi.nlm.nih.gov/geo/). The code can be used to analyze other datasets as long as the raw data and the associated clinical data is available. The configuration of the meta-analysis (*i.e.*, which datasets to include) can be found in the configuration folder `Confs/`.|